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Egg consumption and the risk of type 2 diabetes mellitus: a case–control study

  • Lina Radzevičienė (a1) and Rytas Ostrauskas (a1)
Abstract
Objective

Type 2 diabetes mellitus appears to involve an interaction between susceptible genetic backgrounds and environmental factors including highly calorific diets. As it is important to identify modifiable risk factors that may help reduce the risk of type 2 diabetes mellitus, the aim of the present study was to determine the association between egg consumption and the risk of type 2 diabetes mellitus.

Design

A specifically designed questionnaire was used to collect information on possible risk factors of type 2 diabetes mellitus. The odds ratios and 95 % confidence intervals for type 2 diabetes mellitus were calculated by conditional logistic regression.

Setting

A case–control study in a Lithuanian out-patient clinic was performed in 2001.

Subjects

A total of 234 cases with a newly confirmed diagnosis of type 2 diabetes mellitus and 468 controls free of the disease.

Results

Variables such as BMI, family history of diabetes, cigarette smoking, education, morning exercise and plasma TAG level were retained in multivariate logistic regression models as confounders because their inclusion changed the value of the odds ratio by more than 10 % in any exposure category. After adjustment for possible confounders more than twofold increased risk of type 2 diabetes mellitus was determined for individuals consuming 3–4·9 eggs/week (OR = 2·60; 95 % CI 1·34, 5·08) and threefold increased risk of the disease was determined for individuals consuming ≥5 eggs/week (OR = 3·02; 95 % CI 1·14, 7·98) compared with those eating <1 egg/week.

Conclusions

Our data support a possible relationship of egg consumption and increased risk of type 2 diabetes mellitus.

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Corresponding author
*Corresponding author: Email lina_radzeviciene@yahoo.com
References
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1. Zimmet, P, Alberti, KG & Shaw, J (2001) Global and societal implications of the diabetes epidemic. Nature 414, 782787.
2. Wild, S, Roglic, G, Green, A et al. (2004) Global prevalence of diabetes. Estimates for the year 2000 and projections for 2030. Diabetes Care 27, 10471053.
3. Norkus, A, Domarkienė, S, Šulcaitė, R et al. (2002) [Prevalence of carbohydrate disorders in Kaunas middle-age population]. Lietuvos endokrinologija 10, 6066.
4. Naser, KA, Gruber, A & Thomson, GA (2006) The emerging pandemic of obesity and diabetes: are we doing enough to prevent a disaster? Int J Clin Pract 60, 10931097.
5. Song, WO & Kerver, JM (2000) Nutritional contribution of eggs to American diets. J Am Coll Nutr 19, 5 Suppl., 556S562S.
6. Hu, FB, Manson, JE & Willett, WC (2001) Types of dietary fat and risk of coronary heart disease: a critical review. J Am Coll Nutr 20, 519.
7. Herron, KL & Fernandez, ML (2004) Are the current dietary guidelines regarding egg consumption appropriate? J Nutr 134, 187190.
8. Lithuanian Department of Statistics (2009) Food Consumption. http://www.stat.gov.lt/lt/pages/view/?id=1241 (accessed November 2010).
9. Physicians Committee for Responsible Medicine (2008) Increased Egg Consumption Linked to Mortality. http://www.pcrm.org/health/veginfo/vegetarian_foods.html (accessed September 2010).
10. World Health Organization (1999) Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications. Report of a WHO Consultation. Geneva: WHO.
11. World Health Organization (1995) Physical Status: The Use and Interpretation of Anthropometry. Report of a WHO Expert Committee. WHO Technical Report Series no. 854. Geneva: WHO.
12. Garrow, JS & Webster, J (1985) Quetelet's index (W/H2) as a measure of fatness. Int J Obes 9, 147153.
13. Woodward, M (1999) Case–control studies. In Epidemiology Study Design and Data Analysis, pp. 243289. New York: Chapman, Hall/CRC.
14. Djoussé, L, Gaziano, JM, Buring, JE et al. (2009) Egg consumption and risk of type 2 diabetes in men and women. Diabetes Care 32, 295300.
15. Shi, Z, Yuan, B, Zhang, C et al. (2011) Egg consumption and the risk of diabetes in adults, Jiangsu, China. Nutrition 27, 194198.
16. Djoussé, L, Kamineni, A, Nelson, TL et al. (2010) Egg consumption and risk of type 2 diabetes in older adults. Am J Clin Nutr 92, 422427.
17. Salmeron, J, Hu, FB, Manson, JE et al. (2001) Dietary fat intake and risk of type 2 diabetes in women. Am J Clin Nutr 73, 10191026.
18. Mente, A, de Koning, L, Shannon, HS et al. (2009) A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease. Arch Intern Med 169, 659669.
19. Weggemans, RM, Zock, PL & Katan, MB (2001) Dietary cholesterol from eggs increases the ratio of total cholesterol to high-density lipoprotein cholesterol in humans: a meta-analysis. Am J Clin Nutr 73, 885891.
20. Knopp, RH, Retzlaff, BM, Walden, CE et al. (1997) A double-blind, randomized, controlled trial of the effects of two eggs per day in moderately hypercholesterolemic and combined hyperlipidemic subjects taught the NCEP step I diet. J Am Coll Nutr 16, 551561.
21. Katz, DL, Evans, MA, Nawaz, H et al. (2005) Egg consumption and endothelial function: a randomized controlled crossover trial. Int J Cardiol 99, 6570.
22. Herron, KL, Vega-Lopez, S, Conde, K et al. (2002) Pre-menopausal women, classified as hypo- or hyperresponders, do not alter their LDL/HDL ratio following a high dietary cholesterol challenge. J Am Coll Nutr 21, 250258.
23. McNamara, DJ (2000) The impact of egg limitations on coronary heart disease risk: do the numbers add up? J Am Coll Nutr 19, 5 Suppl., 540S548S.
24. Spence, JD, Jenkins, DJ & Davignon, J (2010) Dietary cholesterol and egg yolks: not for patients at risk of vascular disease. Can J Cardiol 26, 336339.
25. Vogel, RA (2001) Measurement of endothelial function by brachial artery flow-mediated vasodilation. Am J Cardiol 88, 31E34E.
26. Njike, V, Faridi, Z, Dutta, S et al. (2010) Daily egg consumption in hyperlipidemic adults – effects on endothelial function and cardiovascular risk. Nutr J 9, 28.
27. Feskens, EJ & Kromhout, D (1990) Habitual dietary intake and glucose tolerance in euglycaemic men: the Zutphen Study. Int J Epidemiol 19, 953959.
28. Mutungi, G, Ratliff, J, Puglisi, M et al. (2008) Dietary cholesterol from eggs increases plasma HDL cholesterol in overweight men consuming a carbohydrate-restricted diet. J Nutr 138, 272276.
29. Pearce, KL, Clifton, PM & Noakes, M (2011) Egg consumption as part of an energy-restricted high-protein diet improves blood lipid and blood glucose profiles in individuals with type 2 diabetes. Br J Nutr 105, 584592.
30. Djoussé, L & Gaziano, JM (2008) Egg consumption in relation to cardiovascular disease and mortality: the Physicians’ Health Study. Am J Clin Nutr 87, 964969.
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Public Health Nutrition
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