Skip to main content
×
Home
    • Aa
    • Aa
  • Access
  • Cited by 6
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Lartey, Anna Marquis, Grace S. Mazur, Robert Perez-Escamilla, Rafael Brakohiapa, Lucy Ampofo, William Sellen, Daniel and Adu-Afarwuah, Seth 2014. Maternal HIV is associated with reduced growth in the first year of life among infants in the Eastern region of Ghana: the Research to Improve Infant Nutrition and Growth (RIING) Project. Maternal & Child Nutrition, Vol. 10, Issue. 4, p. 604.


    Mwiru, R. S. Spiegelman, D. Duggan, C. Seage, G. R. Semu, H. Chalamilla, G. Kisenge, R. and Fawzi, W. W. 2014. Growth among HIV-infected Children Receiving Antiretroviral Therapy in Dar es Salaam, Tanzania. Journal of Tropical Pediatrics, Vol. 60, Issue. 3, p. 179.


    Mda, Siyazi Raaij, Joop Villiers, François and Kok, Frans 2013. Impact of Multi-Micronutrient Supplementation on Growth and Morbidity of HIV-Infected South African Children. Nutrients, Vol. 5, Issue. 10, p. 4079.


    Colosimo, Enrico A. Fausto, Maria Arlene Freitas, Marta Afonso and Pinto, Jorge Andrade 2012. Practical modeling strategies for unbalanced longitudinal data analysis. Journal of Applied Statistics, Vol. 39, Issue. 9, p. 2005.


    Venkatesh, Kartik K. Lurie, Mark N. Triche, Elizabeth W. De Bruyn, Guy Harwell, Joseph I. McGarvey, Stephen T. and Gray, Glenda E. 2010. Growth of infants born to HIV-infected women in South Africa according to maternal and infant characteristics. Tropical Medicine & International Health, Vol. 15, Issue. 11, p. 1364.


    Hughes, Roger 2009. In this issue. Public Health Nutrition, Vol. 12, Issue. 06, p. 738.


    ×

Longitudinal growth of infants born to HIV-1-infected mothers in Belo Horizonte, Brazil

  • Maria Arlene Fausto (a1), Mariângela Carneiro (a2), Carlos Maurício F Antunes (a2), Enrico Antônio Colosimo (a3) and Jorge A Pinto (a4)
  • DOI: http://dx.doi.org/10.1017/S136898000800267X
  • Published online: 01 June 2009
Abstract
AbstractObjective

To prospectively evaluate growth parameters assessed by weight and length in infected and uninfected infants born to HIV-1-infected mothers and followed from birth to 18 months.

Methods

A cohort consisting of ninety-seven uninfected and forty-two infected infants born to HIV-infected mothers enrolled from 1995 to 2004, and admitted during their first 3 months of life at a referral Pediatric AIDS Clinic in Belo Horizonte, Brazil. Infants were followed until 18 months of age. Data were analysed using mixed-effects linear regression models for weight and length fitted by restricted maximum likelihood.

Results

Infected infants contributed to 466 weight and 411 recumbent length measurements. Uninfected infants provided 924 weight and 907 length measurements. Mean birth weight and length were similar in both groups, 3·1 (sd 0·4) and 3·0 (sd 0·5) kg, and 48·7 (sd 1·4) and 48·8 (sd 2·9) cm for uninfected and infected infants, respectively. However, HIV-1 infection had an early impact in growth impairment: at 6 months of age, HIV-infected children were 1 kg lighter and 2 cm shorter than the uninfected.

Conclusions

Growth faltering in weight, but not length, in HIV-infected children in Brazil is more marked than that reported in a European cohort, probably reflecting background nutritional deficiencies and concomitant infections. In these settings, early and aggressive nutritional management in HIV-1-infected infants should be a priority intervention associated with the antiretroviral therapy.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Longitudinal growth of infants born to HIV-1-infected mothers in Belo Horizonte, Brazil
      Your Kindle email address
      Available formats
      ×
      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Dropbox account. Find out more about sending content to Dropbox.

      Longitudinal growth of infants born to HIV-1-infected mothers in Belo Horizonte, Brazil
      Available formats
      ×
      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Google Drive account. Find out more about sending content to Google Drive.

      Longitudinal growth of infants born to HIV-1-infected mothers in Belo Horizonte, Brazil
      Available formats
      ×
Copyright
Corresponding author
*Corresponding author: Email mariaarlenefausto@hotmail.com
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

4.J Moye , KC Rich , LA Kalish , AR Sheon , C Diaz , ER Cooper , J Pitt & E Handelsman , for the Women and Infants Transmission Study Group (1996) Natural history of somatic growth in infants born to women infected by human immunodeficiency virus. J Pediatr 128, 5867.

5.VJ Carey , FH Yong , LM Frenkel & RM McKinney (2004) Growth velocity assessment in paediatric AIDS: smoothing, penalized quantile regression and the definition of growth failure. Stat Med 23, 509526.

7.G Verweel , AMC van Rossum , NG Hartwig , TFW Wolfs , HJ Scherpbier & R Groot (2002) Treatment with highly active antiretroviral therapy in human immunodeficiency virus type 1-infected children is associated with a sustained effect on growth. Pediatrics 109, e25; http://www.pediatrics.org/cgi/content/full/109/2/e25

13.P Armitage , G Berry & JNS Matthews (2002) Statistical Methods in Medical Research, 4th ed. London: Blackwell Science.

14.JC Pinheiro & DM Bates (2000) Mixed-effects Models in S and S-Plus. New York: Springer-Verlag.

16.S Guillen , JT Ramos , R Resino , JM Bellón & MA Muñoz (2007) Impact on weight and height with the use of HAART in HIV-infected children. Pediatr Infect Dis J 26, 334338.

17.SA Nachman , JC Lindsey , J Moye , KE Stanley , GM Johnson , PA Krogstad , AA Wiznia & Pediatric AIDS Clinical Trials Group 377 Study Team (2005) Growth of human immunodeficiency virus-infected children receiving highly active antiretroviral therapy. Pediatr Infect Dis J 24, 352357.

18.R Berhane , D Bagenda , L Marum , E Aceng , C Ndugwa , RJ Bosch & K Olness (1997) Growth failure as a prognostic indicator of mortality in pediatric HIV infection. Pediatrics 100, e7.

19.RA Henderson , N Hutton , P Derusso & B Caballero (1997) Viral load is associated with nutritional status in HIV-infected children. Nutrition 13, 269.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Public Health Nutrition
  • ISSN: 1368-9800
  • EISSN: 1475-2727
  • URL: /core/journals/public-health-nutrition
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords: