Skip to main content Accessibility help
×
Home
Hostname: page-component-544b6db54f-rcd7l Total loading time: 0.16 Render date: 2021-10-16T00:39:20.786Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

Cavernosal Alpha-Blockade: A New Technique for Investigating and Treating Erectile Impotence

Published online by Cambridge University Press:  29 January 2018

G. S. Brindley*
Affiliation:
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF

Summary

Intracavernosal injection of phenoxybenzamine, in a dose too small to have significant general effects, caused full erection lasting between half an hour and 30 hours in 3 of 4 potent men (2 normal, 2 anorgasmic) and in 6 of 11 impotent men. In the remaining potent man and 3 of the remaining impotent it caused the penis to be stiff enough for intromission. Six of the eleven impotent men have had sexual intercourse, for the first time for months or years, while under the drug.

The practical implications of this new discovery are discussed.

Type
Research Article
Copyright
Copyright © 1983 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Brindley, G. S. (1981) Electroejaculation: its technique, neurological implications and uses. Journal of Neurology, Neurosurgery and Psychiatry, 44, 918.CrossRefGoogle ScholarPubMed
Brindley, G. S. (1983) Physiology of erection and management of paraplegic infertility. In Male Infertility (ed. Hargreave, T. B.). New York: Springer.Google Scholar
Brindley, G. S. & Gillan, P. (1982) Men and women who do not have orgasms. British Journal of Psychiatry, 140, 351–6.CrossRefGoogle Scholar
Boreham, P. F., Braithwaite, P., Milewski, P. & Pearson, H. (1977) Alpha-adrenergic blockers in prostatism. British Journal of Surgery, 64, 756–7.CrossRefGoogle ScholarPubMed
Caine, M., Perleberg, S. & Meretyk, S. (1978) A placebo-controlled double-blind study of the effect of phenoxybenzamine in benign prostatic obstruction. British Journal of Urology, 50, 551–4.CrossRefGoogle ScholarPubMed
Polak, J. M., Gu, J., Mina, S. & Bloom, S. R. (1981) Vipergic nerves in the penis. Lancet, ii, 217–19.Google Scholar
Wagner, G. & Brindley, G. S. (1980) The effect of atropine, α- and β-blockers on human penile erection: a controlled pilot study. In Vasculogenic Impotence (eds. Zorgniotti, A. and Rossi, G.). Springfield, Illinois: Charles C. Thomas.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.
378
Cited by

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Cavernosal Alpha-Blockade: A New Technique for Investigating and Treating Erectile Impotence
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Cavernosal Alpha-Blockade: A New Technique for Investigating and Treating Erectile Impotence
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Cavernosal Alpha-Blockade: A New Technique for Investigating and Treating Erectile Impotence
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *