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Acromegaly and Depression

  • A. Margo (a1)

There is only a small literature on the psychiatric complications of acromegaly. Manfred Bleuler (1954) reported an acromegalic man who had blunted affect and apathy and suggested that this clinical picture represented a special variation of the endocrine psychosyndrome. Avery (1973) reported a further case of depression and anxiety in association with the illness. There are relevant reviews by Michael and Gibbons (1963), Beumont (1972), Labhart (1974) and Lishman (1978).

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Avery, T. L. (1973) A case of acromegaly and gigantism with depression. British Journal of Psychiatry, 122, 599600.
Beumont, P. J. V. (1972) Endocrines and psychiatry. British Journal of Hospital Medicine, 7, 485–97.
Bleuler, M. (1954) Endrokrinologische Psychiatric. Stuttgart: Georg Thieme.
Checkley, S. A., Slade, A. P. & Shur, E. (1981) Growth hormone and other responses to clonidine in patients with endogenous depression. British Journal of Psychiatry, 138, 51–5.
Labhart, A. (1974) Clinical Endocrinology. New York: Springer.
Lehman, W. A. (1978) Organic Psychiatry. Oxford: Blackwell.
Michael, R. & Gibbons, J. (1963) Inter-relationships between the endocrine system and neuropsychiatry. International Review of Neurobiology, 5, 243302.
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Acromegaly and Depression

  • A. Margo (a1)
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