Skip to main content
×
×
Home

Continuing Clozapine Despite Neutropenia

  • Michael L. Wesson (a1), David M. Finnegan (a1) and Peter I. Clark (a2)
Abstract
Background

A 40-year-old chronic schizophrenic patient whose psychosis and associated violent behaviour resolved on clozapine, required chemotherapy for a testicular teratoma with pulmonary metastases. His treatment was initially delayed due to refusal to consent.

Treatment

The patient finally agreed to orchidectomy and cytotoxic therapy, and following agreement by the CPMS, clozapine continued to be dispensed despite neutropenia and ‘red alert’ status on full blood count.

Discussion

This is the only patient to continue clozapine despite ‘red alert’ status, and as such is an exceptional case, but may open the way for such patients in the future.

Copyright
Corresponding author
Michael L. Wesson, Mossley House, Mossley Hill Hospital, Park Avenue, Mossley Hill, Liverpool L18 8BU
References
Hide All
Alvir, J. M. J., Lieberman, J. A., Safferman, A. Z., et al (1993) Clozapine induced agranulocytosis: incidence and risk factors in the United States. New England Journal of Medicine, 329, 162167.
Atkin, K. & Veys, P. (1994) Clozapine-induced neutropenia, or not (letter). British Journal of Psychiatry, 165, 407408.
Beer, D., Cope, S., Paton, C., et al (1994) Clozapine-induced neutropenia – or not (letter). British Journal of Psychiatry, 164, 850.
Re C High Court of Justice (Family Division) (1993) Case number 6703/93.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 13 *
Loading metrics...

Abstract views

Total abstract views: 49 *
Loading metrics...

* Views captured on Cambridge Core between 2nd January 2018 - 25th May 2018. This data will be updated every 24 hours.

Continuing Clozapine Despite Neutropenia

  • Michael L. Wesson (a1), David M. Finnegan (a1) and Peter I. Clark (a2)
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *