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Correlations Between Akathisia and Residual Psychopathology: A By-product of Neuroleptic-Induced Dysphoria

  • John W. Newcomer (a1), L. Stephen Miller (a2), William O. Faustman (a3), Martin W. Wetzel (a4), George P. Vogler (a5) and John G. Csernansky (a6)...
Abstract

Patients developing neuroleptic-induced akathisia have been reported to show higher levels of psychopathology. We sought to replicate this finding and determine its symptom specificity. We confirmed a significant relationship between ratings of akathisia and total score on the Brief Psychiatric Rating Scale (BPRS) during both acute and maintenance neuroleptic treatment. Using stepwise regression models, BPRS anxious-depressive subscale scores were the strongest predictors of akathisia during both treatment conditions. Paranoid subscale scores predicted akathisia only during maintenance treatment. These results suggest that neuroleptic-induced dysphoria largely explains the relationship between akathisia and residual psychopathology during both acute and maintenance neuroleptic treatment.

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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Correlations Between Akathisia and Residual Psychopathology: A By-product of Neuroleptic-Induced Dysphoria

  • John W. Newcomer (a1), L. Stephen Miller (a2), William O. Faustman (a3), Martin W. Wetzel (a4), George P. Vogler (a5) and John G. Csernansky (a6)...
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