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Effectiveness of group body psychotherapy for negative symptoms of schizophrenia: Multicentre randomised controlled trial

  • S. Priebe (a1), M. Savill (a1), T. Wykes (a2), R. P. Bentall (a3), U. Reininghaus (a4), C. Lauber (a5), S. Bremner (a6), S. Eldridge (a7) and F. Röhricht (a1)...

Negative symptoms of schizophrenia have a severe impact on functional outcomes and treatment options are limited. Arts therapies are currently recommended but more evidence is required.


To assess body psychotherapy as a treatment for negative symptoms compared with an active control (trial registration: ISRCTN84216587).


Schizophrenia out-patients were randomised into a 20-session body psychotherapy or Pilates group. The primary outcome was negative symptoms at end of treatment. Secondary outcomes included psychopathology, functional, social and treatment satisfaction outcomes at treatment end and 6-months later.


In total, 275 participants were randomised. The adjusted difference in negative symptoms was 0.03 (95% CI –1.11 to 1.17), indicating no benefit from body psychotherapy. Small improvements in expressive deficits and movement disorder symptoms were detected in favour of body psychotherapy. No other outcomes were significantly different.


Body psychotherapy does not have a clinically relevant beneficial effect in the treatment of patients with negative symptoms of schizophrenia.

Corresponding author
S. Priebe, Unit for Social and Community Psychiatry, WHO Collaborative Centre for Mental Health Services Development, Queen Mary University of London, London E13 8SP, UK. Email:
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See editorial, pp. 6–8, this issue.

Declaration of interest


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1 Saha, S, Chant, D, Welham, J, McGrath, J. A systematic review of the prevalence of schizophrenia. PLoS Med 2005; 2: e141.
2 Kirkpatrick, B, Fenton, WS, Carpenter, WT Jr, Marder, SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull 2006; 32: 214–9.
3 Horan, WP, Kring, AM, Gur, RE, Reise, SP, Blanchard, JJ. Development and psychometric validation of the Clinical Assessment Interview for Negative Symptoms (CAINS). Schizophr Res 2011; 132: 140–5.
4 Hunter, R, Barry, S. Negative symptoms and psychosocial functioning in schizophrenia: neglected but important targets for treatment. Euro Psychiatry 2012; 27: 432–6.
5 Ho, BC, Nopoulos, P, Flaum, M, Arndt, S, Andreasen, NCJ. Two-year outcome in first-episode schizophrenia: predictive value of symptoms for quality of life. Am J Psychiat 1998; 155: 1196–201.
6 National Collaborating Centre for Mental Health. Schizophrenia: The NICE Guideline on Core Interventions in the Treatment and Management of Schizophrenia in Adults in Primary and Secondary Care (CG82). NICE, 2009.
7 National Collaborating Centre for Mental Health. Psychosis and Schizophrenia in Adults: The NICE Guideline on Treatment and Management (CG178). NICE, 2014.
8 Crawford, MJ, Killaspy, H, Barnes, TR, Barrett, B, Byford, S, Clayton, K, et al. Group art therapy as an adjunctive treatment for people with schizophrenia: a multicentre pragmatic randomised trial. BMJ 2012; 344: e846.
9 Rohricht, F, Priebe, SG. Effect of body-oriented psychological therapy on negative symptoms in schizophrenia: a randomized controlled trial. Psychol Med 2006; 36: 669–78.
10 Darby, J. Alteration of some body image indexes in schizophrenia. J Consult Clin Psych 1970; 35: 116–21.
11 Nitsun, M, Stapleton, JH, Bender, M. Movement and drama therapy with long-stay schizophrenics. Br J Med Psychol 1974; 47: 101–19.
12 Goertzel, V, May, PR, Salkin, J, Schoop, T. Body-ego technique: an approach to the schizophrenic patient. J Nerv Ment Dis 1965; 141: 5360.
13 Priebe, S, Röhricht, F. Specific body image pathology in acute schizophrenia. Psychiatry Res 2001; 101: 289301.
14 Röhricht, F, Priebe, S. Disturbances of body experience in schizophrenic patients [in German]. Fortschr Neurol Psychiatr 1997; 65: 323–36.
15 Priebe, S, Savill, M, Reininghaus, U, Wykes, T, Bentall, R, Lauber, C, et al. Effectiveness and cost-effectiveness of body psychotherapy in the treatment of negative symptoms of schizophrenia – a multi-centre randomised controlled trial. BMC Psychiatry 2013; 13: 26.
16 World Health Organization. International Statistical Classification of Diseases and Related Health Problems (Tenth Revision) (ICD-10). WHO, 1992.
17 Kay, SR, Flszbein, A, Opfer, LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bull 1987; 13: 261–76.
18 Priebe, S, Huxley, P, Knight, S, Evans, S. Application and results of the Manchester Short Assessment of Quality of Life (MANSA). Int J Soc Psychiatry 1999; 45: 712.
19 Priebe, S, Watzke, S, Hansson, L, Burns, T. Objective social outcomes index (SIX): a method to summarise objective indicators of social outcomes in mental health care. Acta Psychiatr Scand 2008; 118: 5763.
20 Addington, D, Addington, J, Maticka-Tyndale, E. Assessing depression in schizophrenia: the Calgary Depression Scale. Br J Psychiatry 1993; 163 (suppl 22): 3944.
21 Dunn, M, O'Driscoll, C, Dayson, D, Wills, W, Leff, J. The TAPS Project. 4: an observational study of the social life of long-stay patients. Br J Psychiatry 1990; 157: 842–8.
22 Office for National Statistics. The United Kingdom 2000 Time Use Survey – Technical Report. ONS, 2003.
23 Nguyen, TD, Attkisson, CC, Stegner, BL. Assessment of patient satisfaction: development and refinement of a service evaluation questionnaire. Eval Program Plann 1983; 6: 299313.
24 Simpson, G, Angus, J. A rating scale for extrapyramidal side effects. Acta Psychiat Scand 1970; 45: 11–9.
25 Marder, SR, Davis, JM, Chouinard, G. The effects of risperidone on the five dimensions of schizophrenia derived by factor analysis: combined results of the North American trials. J Clin Psychiat 1997; 58: 538–46.
26 Chisholm, D, Knapp, MRJ, Knudsen, HC, Amaddeo, F, Gaite, L, Van Wijngaarden, B. Client Socio-Demographic and Service Receipt Inventory – European Version: development of an instrument for international research. EPSILON Study 5. Br J Psychiatry 2000; 177 (suppl 39): s2833.
27 Szende, A, Oppe, M, Devlin, NJ. EQ-5D Value Sets: Inventory, Comparative Review and User Guide. Springer, 2007.
28 Rohricht, F. Body-Oriented Psychotherapy in Mental Illness: A Manual for Research and Practice. Hogrefe, 2000.
29 Röhricht, F. Body oriented psychotherapy. The state of the art in empirical research and evidence-based practice: a clinical perspective. Body Mov Dance Psychother 2009; 4: 135–56.
30 Röhricht, F, Papadopoulos, N, Priebe, S. An exploratory randomized controlled trial of body psychotherapy for patients with chronic depression. J Affect Disord 2013; 151: 8591.
31 Gold, C, Solli, HP, Krüger, V, Lie, SA. Dose–response relationship in music therapy for people with serious mental disorders: systematic review and meta-analysis. Clinical Psychol Rev 2009; 29: 193207.
32 Newham, E. Pilates Union UK: Comprehensive Matwork Manual. Pilates Union UK, 2010.
33 Angrist, JD, Imbens, GW, Rubin, DB. Identification of causal effects using instrumental variables. J Am Stat Assoc 1996; 91: 444–55.
34 Adams, M, Caldwell, K, Atkins, L, Quin, R. Pilates and mindfulness: a qualitative study. J Dance Educ 2012; 12: 123–30.
35 Khoury, B, Lecomte, T, Gaudiano, A, Paquin, K. Mindfulness interventions for psychosis: a meta-analysis. Schizophr Res 2013; 150: 176–84.
36 Savill, M, Banks, C, Khanom, H, Priebe, S. Do negative symptoms of schizophrenia change over time? A meta-analysis of longitudinal data. Psychol Med 2015; 45: 1613–27.
37 Ren, J, Xia, J. Dance therapy for schizophrenia. Cochrane Database Syst Rev 2013; 10: CD006868.
38 Mössler, K, Chen, X, Heldal, TO, Gold, C. Music therapy for people with schizophrenia and schizophrenia-like disorders. Cochrane Database Syst Rev 2011; 12: CD004025.
39 Blanchard, JJ, Kring, AM, Horan, WP, Gur, R. Toward the next generation of negative symptom assessments: the collaboration to advance negative symptom assessment in schizophrenia. Schizophrenia Bull 2011; 37: 291–9.
40 Blanchard, JJ, Cohen, AS. The structure of negative symptoms within schizophrenia: implications for assessment. Schizophr Bull 2006; 32: 238–45.
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Effectiveness of group body psychotherapy for negative symptoms of schizophrenia: Multicentre randomised controlled trial

  • S. Priebe (a1), M. Savill (a1), T. Wykes (a2), R. P. Bentall (a3), U. Reininghaus (a4), C. Lauber (a5), S. Bremner (a6), S. Eldridge (a7) and F. Röhricht (a1)...
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