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Season of birth and anorexia nervosa

  • Giulio Disanto (a1), Adam E. Handel (a1), Andrea E. Para (a1), Sreeram V. Ramagopalan (a2) and Lahiru Handunnetthi (a3)...
Summary

Our aim was to investigate whether there is a season-of-birth effect in anorexia nervosa. In a meta-analysis, we compared the distribution of anorexia births (n = 1293) from four independent UK cohorts to that of the general UK population (n = 21 914 037), using both the Walter & Elwood seasonality and chi-squared tests. We found an excess of anorexia births from March to June (odds ratio (OR) = 1.15, 95% CI 1.03–1.29, P = 0.012) and a deficit from September to October (OR = 0.8, 95% CI 0.68–0.94, P = 0.007). These results indicate that environmental risk factor(s) are operative during gestation or immediately after birth and their identification will be important for disease prevention strategies.

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Copyright
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial licence (http://creativecommons.org/licenses/by-nc/4.0/), which permits noncommercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Corresponding author
Lahiru Handunnetthi, The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Headington, Oxford OX3 7BN, UK. Email: lahiruh@well.ox.ac.uk
Footnotes
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This work was supported by the Wellcome Trust (075491/Z/04).

Declaration of interest

None.

Footnotes
References
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Supplementary materials

Disanto et al. supplementary material
Supplementary Table S1

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Supplementary materials

Disanto et al. supplementary material
Supplementary Table S1

 PDF (38 KB)
38 KB
PDF
Supplementary materials

Disanto et al. supplementary material
Supplementary Table S1

 PDF (38 KB)
38 KB

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Season of birth and anorexia nervosa

  • Giulio Disanto (a1), Adam E. Handel (a1), Andrea E. Para (a1), Sreeram V. Ramagopalan (a2) and Lahiru Handunnetthi (a3)...
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