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Induction of Rapid Metabolism of Metolachlor in Sorghum (Sorghum bicolor) Shoots by CGA-92194 and Other Antidotes

Published online by Cambridge University Press:  12 June 2017

E. Patrick Fuerst  and
John W. Gronwald
E. Patrick Fuerst
Affiliation:
U.S. Dep. Agric., Agric Res. Serv., Univ. Minnesota, St. Paul, MN 55108
John W. Gronwald
Affiliation:
Dep. Agron. and Plant Genetics, Univ. Minnesota, St. Paul, MN 55108
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Abstract

Sorghum [Sorghum bicolor (L.) Moench. ‘G-623 GBR’] bioassays indicated that shoot growth was more susceptible to metolachlor [2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)acetamide] and more responsive to the antidote CGA-92194 {α-[(1,3-dioxolan-2-yl-methoxy)-imino] benzeneacetonitrile} than root growth. Seed treatment with CGA-92194 increased seedling shoot tolerance to metolachlor approximately tenfold. CGA-92194 seed treatment enhanced shoot absorption of 14C-metolachlor approximately twofold. Metolachlor was initially metabolized to the glutathione conjugate in untreated shoots and those treated with CGA-92194. However, CGA-92194 seed treatment caused accelerated metolachlor metabolism in the shoot, decreasing metolachlor content and increasing formation of the glutathione conjugate. Cyometrinil {(Z)-α[(cyanomethoxy)imino] benzeneacetonitrile}, flurazole [phenylmethyl 2-chloro-4-(trifluoromethyl)-5-thiazolecarboxylate], naphthalic anhydride (1H,3H-naphtho[1,8-cd]-pyran-1,3-dione), and dichlormid (2,2-dichloro-N,N-di-2-propenylacetamide) also protected sorghum from metolachlor injury and enhanced metolachlor absorption and metabolism. The degree of protection conferred by a particular antidote was correlated with its ability to enhance metabolism of metolachlor in shoot tissue. These results are consistent with the hypothesis that the above antidotes protect sorghum from metolachlor injury by inducing rapid detoxification of metolachlor through conjugation with glutathione.

Keywords

Herbicide metabolismherbicide absorptionCGA-43089cyometrinilnaphthalic anhydrideR-25788dichlormidMON-4606flurazole
Type
Physiology, Chemistry, and Biochemistry
Information
Weed Science , Volume 34 , Issue 3 , May 1986 , pp. 354 - 361
Copyright
Copyright © 1986 by the Weed Science Society of America 

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References

Literature Cited

1. Devlin, D. L., Moshier, L. J., Russ, O. G., and Stahlman, P. W. 1983. Antidotes reduce injury to grain sorghum (Sorghum bicolor) from acetanilide herbicides. Weed Sci. 31:790–795.Google Scholar
2. Ebert, E. 1982. The role of waxes in the uptake of metolachlor into sorghum in relation to the protectant CGA-43089. Weed Res. 22:305–311.Google Scholar
3. Ellis, J. F., Peek, J. W., Boehle, J. Jr., and Muller, G. 1980. Effectiveness of a new safener for protecting sorghum (Sorghum bicolor) from metolachlor injury. Weed Sci. 28:1–5.Google Scholar
4. Fuerst, E. P. and Gronwald, J. W. 1984. Studies on metolachlor and CGA-92194 modes of action. Proc. North Cent. Weed Control Conf. 39:87.Google Scholar
5. Hatzios, K. K. 1983. Effects of CGA-43089 on responses of sorghum (Sorghum bicolor) to metolachlor combined with ozone or antioxidants. Weed Sci. 31:280–284.Google Scholar
6. Hatzios, K. K. 1984. Herbicide antidotes: development, chemistry, and mode of action. Adv. Agron. 36:265–316.Google Scholar
7. Jackson, L. A. and Kapusta, G. 1984. Mode of action of flurazole safener in grain sorghum. Proc. North Cent. Weed Control Conf. 39:76.Google Scholar
8. Jordan, L. S. and Joliffe, V. A. 1971. Protection of plants from herbicides with 1,8-naphthalic anhydride as illustrated with sorghum. Bull. Environ. Contam. Toxicol. 6:417–421.CrossRefGoogle Scholar
9. Ketchersid, M. L., Norton, K., and Merkle, M. G. 1981. Influence of soil moisture on the safening effect of CGA-43089 in grain sorghum (Sorghum bicolor). Weed Sci. 29:281–287.Google Scholar
10. Ketchersid, M. L., Vietor, D. M., and Merkle, M. G. 1982. CGA-43089 effects on metolachlor uptake and membrane permeability in grain sorghum (Sorghum bicolor). J. Plant Growth Regul. 1:285–294.Google Scholar
11. Lamoureux, G. L. and Rusness, D. G. 1983. Malonylcysteine conjugates as end-products of glutathione conjugate metabolism in plants. Pages 295–300 in Miyamoto, J. et al., ed. IUPAC Pesticide Chemistry: Human Welfare and the Environment. Pergamon Press, New York.Google Scholar
12. Lamoureux, G. L., Stafford, L. E., and Tanaka, F. S. 1971. Metabolism of 2-chloro-N-isopropylacetanilide (propachlor) in the leaves of corn, sorghum, sugarcane, and barley. J. Agric. Food Chem. 19:346–350.Google Scholar
13. Nyffeler, A., Gerber, H. R., and Hensley, J. R. 1980. Laboratory studies on the behavior of the herbicide safener CGA-43089. Weed Sci. 28:6–10.Google Scholar
14. Simkins, G. S., Moshier, L. J., and Russ, O. G. 1980. Influence of acetamide herbicide applications on efficacy of the protectant CGA-43089 in grain sorghum (Sorghum bicolor). Weed Sci. 28:646–649.Google Scholar
15. Spotanski, R. F. and Burnside, O. C. 1973. Reducing herbicide injury to sorghum with crop protectants. Weed Sci. 21:531–536.CrossRefGoogle Scholar
16. Warmund, M. R., Kerr, H. D., and Peters, E. J. 1985. Lipid metabolism in grain sorghum (Sorghum bicolor) treated with alachlor plus flurazole. Weed Sci. 33:25–28.Google Scholar
17. Winkle, M. E., Leavitt, J.R.C., and Burnside, O. C. 1980. Acetanilide-antidote combinations for weed control in corn (Zea mays) and sorghum (Sorghum bicolor). Weed Sci. 28:699–704.CrossRefGoogle Scholar