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Phytochemistry and beneficial impacts of cinnamon (Cinnamomum zeylanicum) as a dietary supplement in poultry diets

  • M. SAEED (a1), A.A. KAMBOH (a2), S.F. SYED (a3), D. BABAZADEH (a4), I. SUHERYANI (a5), Q.A. SHAH (a3), M. UMAR (a3), I. KAKAR (a6), M. NAVEED (a7), M.E. ABD EL-HACK (a8), M. ALAGAWANY (a8) and S. CHAO (a1)...
Abstract

Cinnamon is a common spice obtained from the bark of the cinnamon tree (Cinnamomum zeylanicum). It has been used for culinary, as well as medicinal, purposes since ancient times in various countries. Apart from substantial amounts of several nutrients, including carbohydrates, proteins, choline, vitamins (A, K, C, B3), and minerals, several biological active compounds are present in the extract of oil, which contribute to immunomodulatory, antioxidant, antiviral, lowering blood cholesterol, antimicrobial, lipid-lowering, antihypertension, anti-inflammatory, antitumor, gastroprotective, antidiabetic, neuroprotective and blood purifying properties. Cinnamon roots serve as a hepatic stimulant by improving bile production, eliminating toxins, restoring electrolyte balance and regulating hydration and can be used for enhancing digestion. In addition, nutritional properties of cinnamon powder include positive effects regarding growth, digestion, enhanced activity of gut microflora, improvement of immune response, as well as improved feed efficiency and health improvement of poultry birds. Recently, research focus has been directed towards supplementing broiler diets with cinnamon powder as a phytobiotic in order to replace synthetic growth promoters. After reviewing the literature, it was found that the research at the molecular level to elucidate the mechanisms behind the potential of cinnamon as a feed additive in poultry is limited, despite its promising impacts. Furthermore, supplementation doses vary significantly, i.e., from 0.02 to 7%. So, the aim of this review was to compile the published research related to cinnamon. Hence explore its beneficial properties, find out its optimal dosage for uses by veterinarians, researchers, and nutritionists, as well as its potential to use as a natural feed additive to replace the synthetic antibiotic growth promoters in poultry feed.

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Corresponding authors: drasgharkamboh@yahoo.com; sunchao2775@163.com
References
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AGUIHE, P.C., KEHINDE, A.S., OSPINA-ROJAS, I.C. and MURAKAMI, A.E. (2017) Comparative effect of different detoxified rubber seed meal on haematological and serum biochemical indices of broilers. Journal of Animal Health and Production 5: 50-57.
ALI, A.B.E. (2015) Effect of feeding cinnamon as growth promoter on broiler chick's performance and meat quality. http://khartoumspace.uofk.edu/123456789/24311.
ALI, A.H., ABDUL-AZEEZ, L.A., HUMOOD, J.K., ALI, Z.A., HELAL, Z.H. and WAHAB, F.L. (2016) The effect of ethanolic extract of hibiscus sabdariffa on some physiological and antioxidant parameters in female rabbits. Journal of Animal Health and Production 4: 37-41.
AL-JIFFRI, O., EL-SAYED, Z. and AL-SHARIF, F. (2011) Urinary tract infection with Escherichia coli and antibacterial activity of some plants extracts. International Journal of Microbiology Research 2: 01-07.
AL-KASSIE, G.A. (2009) Influence of two plant extracts derived from thyme and cinnamon on broiler performance. Pakistan Veterinary Journal 29: 169-173.
ALQASOUMI, S. (2012) Anti-secretagogue and antiulcer effects of cinnamon cinnamomum zeylanicum in rats. Journal of Pharmacognosy and Phytotherapy 4: 53-61.
ALQASOUMI, S., AL-DOSARY, M., AL-YAHYA, M. and AL-MOFLEH, I. (2011) Gastroprotective effect of a popular spice cinnamon “Cinnamomum zeylanicum” in rats. European Journal of Pharmacology 668: e42.
ALTSCHULER, J.A., CASELLA, S.J., MACKENZIE, T.A. and CURTIS, K.M. (2007) The effect of cinnamon on a1c among adolescents with type 1 diabetes. Diabetes care 30: 813-816.
AMR, R. and MAYSA, E. (2010) Antiulcer effect of cinnamon and chamomile aqueous extracts in rats models. Journal of American Sciences 6: 209-216.
ANDERSON, R.A., BROADHURST, C.L., POLANSKY, M.M., SCHMIDT, W.F., KHAN, A., FLANAGAN, V.P., SCHOENE, N.W. and GRAVES, D.J. (2004) Isolation and characterization of polyphenol type-a polymers from cinnamon with insulin-like biological activity. Journal of Agricultural and Food Chemistry 52: 65-70.
ARAIN, M.A., MEI, Z., HASSAN, F.U., SAEED, M., ALAGAWANY, M., SHAR, A.H. and RAJPUT, I.R. (2018) Lycopene: a natural antioxidant for prevention of heat-induced oxidative stress in poultry. World's Poultry Science Journal74 (1) (Accepted).
BANSODE, V. (2012) A review on pharmacological activities of Cinnamomum cassia Blume. International Journal of Green Pharmacy 6: 102.
BARCELOUX, D.G. (2009) Cinnamon (cinnamomum species). Disease-a-Month 55: 327-335.
BEDFORD, M. (2000) Removal of antibiotic growth promoters from poultry diets: Implications and strategies to minimise subsequent problems. World's Poultry Science Journal 56: 347-365.
CALUCCI, L., PINZINO, C., ZANDOMENEGHI, M., CAPOCCHI, A., GHIRINGHELLI, S., SAVIOZZI, F., TOZZI, S. and GALLESCHI, L. (2003) Effects of gamma-irradiation on the free radical and antioxidant contents in nine aromatic herbs and spices. Journal of Agricultural and Food Chemistry 51: 927-934.
CHANG, S.T. and CHENG, S.S. (2002) Antitermitic activity of leaf essential oils and components from cinnamomum osmophleum. Journal of Agricultural & Food Chemistry 50: 1389-1392.
CHANGXING, L., CHENLING, M., ALAGAWANY, M., JIANHUA, L., DONGFANG, D., GAICHAO, W., WENYIN, Z., SYED, S.F., ARAIN, M.A., SAEED, M., HASSAN, F.U. and CHAO, S. (2018) Health benefits and potential applications of anthocyanins in poultry feed industry. World's Poultry Science Journal 74: (Accepted).
CHAUDHARY, S.S., TARIQ, M., ZAMAN, R. and IMTIYAZ, S. (2014) The in vitro anti-acne activity of two unani drugs. Ancient Science of Life 33: 35-38.
CHENG, B. (1983) A review of cinnamon. Zhong Cao Yao 14: 4762-4765.
CHENG, S.S., LIU, J.Y., HSUI, Y.R. and CHANG, S.T. (2006) Chemical polymorphism and antifungal activity of essential oils from leaves of different provenances of indigenous cinnamon (cinnamomum osmophloeum). Bioresource Technology 97: 306-312.
CHERICONI, S., PRIETO, J.M., IACOPINI, P., CIONI, P. and MORELLI, I. (2005) In vitro activity of the essential oil of cinnamomum zeylanicum and eugenol in peroxynitrite-induced oxidative processes. Journal of Agricultural and Food Chemistry 53: 4762-4765.
CIFTCI, M., SIMSEK, U.G., YUCE, A., YILMAZ, O. and DALKILIC, B. (2010) Effects of dietary antibiotic and cinnamon oil supplementation on antioxidant enzyme activities, cholesterol levels and fatty acid compositions of serum and meat in broiler chickens. Acta Veterinaria Brno 79: 33-40.
DHAMA, K., LATHEEF, S.K., MANI, S., SAMAD, H.A., KARTHIK, K., TIWARI, R., KHAN, R.U., ALAGAWANY, M., FARAG, M.R., ALAM, G.M., LAUDADIO, V. and TUFARELLI, V. (2015) Multiple beneficial applications and modes of action of herbs in poultry health and production-a review. International Journal of Pharmacology11: 152-176.
DORMAN, H.J. and DEANS, S.G. (2000) Antimicrobial agents from plants: Antibacterial activity of plant volatile oils. Journal of Applied Microbiology 88: 308-316.
EL-HACK, M.A. and ALAGAWANY, M. (2015) Performance, egg quality, blood profile, immune function, and antioxidant enzyme activities in laying hens fed diets with thyme powder. Journal of Animal and Feed Sciences 24: 127-133.
EUROPEAN MEDICINES AGENCY (2011) Assessment Report on Cinnamomum verum J.S. Presl, cortex and corticis aetheroleum. EMA/HMPC/246773/2009. Available online: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_HMPC_assessment_report/2011/08/WC500110090.pdf.
FAGHANI, M., RAHIMIAN, Y., RAFIEE, A. and NAMJOO, A.R. (2014) Effect of garlic and cinnamon in comparison to virginiamycin on performance and some haematological parameters in broiler chicks. Research Opinions in Animal and Veterinary Sciences 4: 504-507.
FATIMA, M., ZAIDI, N.S., AMRAIZ, D. and AFZAL, F. (2016) In vitro antiviral activity of cinnamomum cassia and its nanopartilces against h7n3 influenza a virus. Journal of Microbiology & Biotechnology 26: 151.
GALIB, A.M., AL-KASSIE, G. and WITWIT, N.M. (2010) A comparative study on diet supplementation with a mixture of herbal plants and dandelion as a source of prebiotics on the performance of broilers. Pakistan Journal of Nutrition 9: 67-71.
GOPI, M., KATHIRVELAN, C., PREMCHANDER, D., VASANTHAKUMAR, P., PANGAYARSELVI, B., SASIKUMAR, P. and CHANDRASEKARAN, D. (2012) Effect of cinnamon powder (cinnamomum zeylanicum) supplementation on growth performance of broilers. Commercial and rural poultry production: Novel concepts and strategies to meet growing demand and changing consumer needs. Proceedings of the 24th Annual Conference and National Symposium of Indian Poultry Science Association, pp. 35-36.
GOWDA, D.C. and SARATHY, C. (1987) Structure of an l -arabino- d -xylan from the bark of cinnamomum zeylanicum. Carbohydrate Research 166: 263-269.
GUERRA, F.Q., MENDES, J.M., SOUSA, J.P., MORAIS-BRAGA, M.F., SANTOS, B.H., MELO COUTINHO, H.D. and LIMA EDE, O. (2012) Increasing antibiotic activity against a multidrug-resistant Acinetobacter spp by essential oils of Citrus limon and Cinnamomum zeylanicum. Natural Products Research 26: 2235-2258.
HARDY, B. (2002) The issue of antibiotic use in the livestock industry: What have we learned? Animal Biotechnology 13: 129.
HASHEMI, S. and DAVOODI, H. (2010) Phytogenics as new class of feed additive in poultry industry. Journal of Animal and Veterinary Advances 9: 2295-2304.
HAYASHI, K., IMANISHI, N., KASHIWAYAMA, Y., KAWANO, A., TERASAWA, K., SHIMADA, Y. and OCHIAI, H. (2007) Inhibitory effect of cinnamaldehyde, derived from cinnamomi cortex, on the growth of influenza a/pr/8 virus in vitro and in vivo. Antiviral Research 74: 1-8.
HOSSEIN, N., ZAHRA, Z., ABOLFAZL, M., MAHDI, S. and ALI, K. (2013) Effect of cinnamon zeylanicum essence and distillate on the clotting time. Journal of Medicinal Plant Research 7: 1339-1343.
IMANI, A., BANI, M.S., NOORI, F., FARZANEH, M. and MOGHANLOU, K.S. (2017) The effect of bentonite and yeast cell wall along with cinnamon oil on aflatoxicosis in rainbow trout (oncorhynchus mykiss): Digestive enzymes, growth indices, nutritional performance and proximate body composition. Aquaculture 476: 160-167.
ISABEL, B. and SANTOS, Y. (2009) Effects of dietary organic acids and essential oils on growth performance and carcass characteristics of broiler chickens. Journal of Applied Poultry Research 18: 472-476.
ISOGAI, A., MURAKOSHI, S., SUZUKI, A. and TAMURA, S. (1977) Chemistry and biological activities of cinnzeylanine and cinnzeylanol, new insecticidal substances from cinnamonum zeylanicum nees. Agricultural and Biological Chemistry 41: 1779-1784.
JAKHETIA, V. (2010) Cinnamon: A pharmacological review. Journal of Advanced Scientific Research 1: 19-23.
JANTAN, I.B., KARIM MOHARAM, B.A., SANTHANAM, J. and JAMAL, J.A. (2008) Correlation between chemical composition and antifungal activity of the essential oils of eight cinnamomum. Species. Pharmaceutical Biology 46: 406-412.
JAYAPRAKASHA, G.K., RAO, L.J. and SAKARIAH, K.K. (2002) Chemical composition of volatile oil from cinnamomum zeylanicum buds. Zeitschrift für Naturforschung C 57: 990-993.
KESKIN, D. and and TOROGLU, S. (2011) Studies on antimicrobial activities of solvent extracts of different spices. Journal of Environmental Biology 32: 251-256.
KHAN, A., SAFDAR, M., KHAN, M.M.A., KHATTAK, K.N. and ANDERSON, R.A. (2003) Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 26: 3215-3218.
KHASNAVIS, S. and PAHAN, K. (2012) Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein dj-1 in astrocytes and neurons. Journal of Neuroimmune Pharmacology 7: 424-435.
KIM, S.H., HYUN, S.H. and CHOUNG, S.Y. (2006) Anti-diabetic effect of cinnamon extract on blood glucose in db/db mice. Journal of Ethnopharmacology 104: 119-123.
KIM, Y.G., LEE, J.H., KIM, S.I., BAEK, K.H. and LEE, J. (2015) Cinnamon bark oil and its components inhibit biofilm formation and toxin production. International Journal of Food Microbiology 195: 30-39.
KOOCHAKSARAIE, R.R., IRANI, M. and GHARAVYSI, S. (2011) The effects of cinnamon powder feeding on some blood metabolites in broiler chicks. Brazilian Journal of Poultry Science 13: 197-201.
KWON, H.K., HWANG, J.S., LEE, C.G., SO, J.S., SAHOO, A., IM, C.R., JEON, W.K., KO, B.S., LEE, S.H., PARK, Z.Y. and IM, S.H. (2011) Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells. World Journal of Gastroenterology 17: 976-986.
LEE, B.J., KIM, Y.J., CHO, D.H., SOHN, N.W. and KANG, H. (2011) Immunomodulatory effect of water extract of cinnamon on anti-cd3-induced cytokine responses and p38, jnk, erk1/2, and stat4 activation. Immunopharmacol Immunotoxicol 33: 714-722.
LEE, C.W., HONG, D.H., HAN, S.B., PARK, S.H., KIM, H.K., KWON, B.M. and KIM, H.M. (1999) Inhibition of human tumor growth by 2'-hydroxy- and 2'-benzoyloxycinnamaldehydes. Planta Medica 65: 263-266.
LEE, E.J., CHEN, H.Y., HUNG, Y.C., CHEN, T.Y., LEE, M.Y., YU, S.C., CHEN, Y.H., CHUANG, I.C. and WU, T.S. (2009) Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia. Experimental Neurology 217: 74-83.
LEE, J.S., CHOI, M.S., JEON, S.M., JEONG, T.S., PARK, Y.B., LEE, M.K. and BOK, S.H. (2001) Lipid-lowering and antioxidative activities of 3,4-di(oh)-cinnamate and 3,4-di(oh)-hydrocinnamate in cholesterol-fed rats. Clinica Chimica Acta 314: 221-229.
LEE, S.H., LEE, S.Y., SON, D.J., LEE, H., YOO, H.S., SONG, S., OH, K.W., HAN, D.C., KWON, B.M. and HONG, J.T. (2005) Inhibitory effect of 2′-hydroxycinnamaldehyde on nitric oxide production through inhibition of NF-κB activation in RAW 264.7 cells. Biochemical Pharmacology 69: 791-799.
LIN, C.C., WU, S.J., CHANG, C.H. and NG, L.T. (2003) Antioxidant activity of cinnamomum cassia. Phytotherapy Research 17: 726-730.
MADAN, M. and KANNAN, S. (2004) . Economics and Marketing of Cinnamon and Cassia–A Global View, in: RAVINDRAN, P.N. & BABU, K.N. (Eds) Cinnamon and Cassia: The Genus Cinnamomum (CRC Press: Boca Raton, FL, USA).
MANDAL, S., DEBMANDAL, M., SAHA, K. and PAL, N.K. (2011) In vitro Antibacterial Activity of three Indian Spices against Methicillin-Resistant Staphylococcus aureus. Oman Medical Journal 26: 319-323.
NADERI, M., AKBARI, M.R., ASADI-KHOSHOEI, E., KHAKSAR, K. and KHAJALI, F. (2014) Effects of dietary inclusion of turmeric (curcuma longa) and cinnamon (cinnamomum verum) powders on performance, organs relative weight and some immune system parameters in broiler chickens. Poultry Science Journal 2:153-163.
NAJAFI, S. and TAHERPOUR, K. (2014) Effects of dietary ginger (zingiber ofjicinale), cinnamon (cinnamo¬mum), synbiotic and antibiotic supplementation on performance of broilers. Journal of Animal Science Advances 4: 658-667.
NAVEED, R., HUSSAIN, I., TAWAB, A., TARIQ, M., RAHMAN, M., HAMEED, S., MAHMOOD, M.S., SIDDIQUE, A.B. and IQBAL, M. (2013) Antimicrobial activity of the bioactive components of essential oils from Pakistani spices against Salmonella and other multi-drug resistant bacteria. BMC Complementary and Alternative Medicine 13: 265-275.
ORAYAGA, K.T., OLUREMI, O.I.A. and ADENKOLA, A.Y. (2016) Effect of water soaking of sweet orange (Citrus sinensis) fruit peels on haematology, carcass yield and internal organs of finisher broiler chickens. Journal of Animal Health and Production 4: 65-71.
OTSUKA, H., FUJIOKA, S., KOMIYA, T., MIZUTA, E. and TAKAMOTO, M. (1982) [studies on anti-inflammatory agents. Vi. Anti-inflammatory constituents of cinnamomum sieboldii meissn (author's transl)]. Yakugaku Zasshi 102: 162-172.
OUSSALAH, M., CAILLET, S. and LACROIX, M. (2006) Mechanism of action of Spanish oregano, Chinese cinnamon, and savoury essential oils against cell membranes and walls of Escherichia coli O157: H7 and Listeria monocytogenes Journal of Food Protection 69: 1046-1055.
PARK, B.S. (2008) Effect of dietary cinnamon powder on savor and quality of chicken meat in broiler chickens. Journal of the Korean Society of Food Science & Nutrition 37: 618-624.
PARK, R.-J. and PARK, Y.-G. (2000) Studies on the effects of the parts of cinamomum cassia presl on the antixidation (ⅰ). The Korea Journal of Herbology 15: 45-45.
PREMANATHAN, M., RAJENDRAN, S., RAMANATHAN, T. and KATHIRESAN, K. (2000) A survey of some Indian medicinal plants for anti-human immunodeficiency virus (hiv) activity. Indian Journal of Medical Research 112: 73.
PREUSS, H.G., ECHARD, B., POLANSKY, M.M. and ANDERSON, R. (2006) Whole cinnamon and aqueous extracts ameliorate sucrose-induced blood pressure elevations in spontaneously hypertensive rats. Journal of the American College of Nutrition 25: 144-150.
QIN, B., NAGASAKI, M., REN, M., BAJOTTO, G., OSHIDA, Y. and SATO, Y. (2003) Cinnamon extract (traditional herb) potentiates in vivo insulin-regulated glucose utilization via enhancing insulin signaling in rats. Diabetes Research and Clinical Practice 62: 139-148.
RANASINGHE, P., GALAPPATHTHY, P., CONSTANTINE, G.R., JAYAWARDENA, R., WEERATUNGA, H.D., PREMAKUMARA, S. and KATULANDA, P. (2017) Cinnamomum zeylanicum (Ceylon cinnamon) as a potential pharmaceutical agent for type-2 diabetes mellitus: study protocol for a randomized controlled trial. Trials 18: 446.
RANATUNGA, J., SENANAYAKE, U. and WIJESEKERA, R. (2004) Cultivation and management of cinnamon. Cinnamon and Cassia The genus Cinnamomum.
RAO, P.V. and GAN, S.H. (2014) Cinnamon: A multifaceted medicinal plant. Evidence Based Complementary and Alternative Medicine: article ID 642942.
SACCA-SIDI, I.Y.M., ALOWANOU, G.G., OLOUNLADÉ, P.A., NADÈGE-DEDEHOU, V.F.G. and HOUNZANGBÉ-ADOTÉ, S.M. (2016) In vitro combined effects of Zanthoxylum zanthoxyloides and Newbouldia laevis methanolic extracts on three life-cycle stages of the parasitic nematode, Haemonchus contortus. Journal of Animal Health and Production 4: 128-133.
SADEGHI, G.H., KARIMI, A., JAHROMI, S.H.P., AZIZI, T. and DANESHMAND, A. (2012) Effects of cinnamon, thyme and turmeric infusions on the performance and immune response in of 1-to 21-day-old male broilers. Brazilian Journal of Poultry Science 14: 15-20.
SAEED, M., BABAZADEH, D., ARIF, M., ARAIN, M.A., BHUTTOZ, A., SHAR, A.H., KAKAR, M.U., ANZOOR, R. and CHAO, S. (2017a) Silymarin: a potent hepatoprotective agent in poultry industry. World's Poultry Science Journal 73 (3): 483-492.
SAEED, M., BALOCH, A.R., WANG, M., SOOMRO, R.N., BALOCH, A.M., BUX, B.A., ARIAN, M.A., FARAZ, S.S. and ZAKRIYA, H.M. (2015) Use of cichorium intybus leaf extract as growth promoter, hepatoprotectant and immune modulent in broilers. Journal of Animal Production Advances 5: 585-591.
SAEED, M., NAVEED, M., ARAIN, M.A., ARIF, M., EL-HACK, M.E.A., ALAGAWANY, M., SIYAL, F.A., SOOMRO, R.N. and SUN, C. (2017b) Quercetin: Nutritional and beneficial effects in poultry. Worlds Poultry Science Journal 73: 355-364.
SAEED, M., XU, Y.T., REHMAN, Z.U., ARAIN, M.A., SOOMRO, R.N., ABD EL-HACK, M.E., BHUTTO, Z.A., ABBASI, B., DHAMA, K., SARWAR, M. and CHAO, S. (2017c) Nutritional and healthical aspects of yacon (smallanthus sonchifolius) for human, animals and poultry. International Journal of Pharmacology 13: 361-369.
SANGOH, P., CHAEMIN, R., BYUNGSUNG, P. and JONG, H. (2013) The meat quality and growth performance in broiler chickens fed diet with cinnamon powder. Journal of Environmental Biology 34: 127.
SCHOENE, N.W., KELLY, M.A., POLANSKY, M.M. and ANDERSON, R.A. (2005) Water-soluble polymeric polyphenols from cinnamon inhibit proliferation and alter cell cycle distribution patterns of hematologic tumor cell lines. Cancer Letters 230: 134-140.
SHEN, Y., FUKUSHIMA, M., ITO, Y., MURAKI, E., HOSONO, T., SEKI, T. and ARIGA, T. (2010) Verification of the antidiabetic effects of cinnamon (cinnamomum zeylanicum) using insulin-uncontrolled type 1 diabetic rats and cultured adipocytes. Bioscience Biotechnology and Biochemistry 74: 2418-2425.
ŞIMŞEK, Ü.G., ÇIFTÇI, M., DOĞAN, G. and ÖZÇELIK, M. (2013) Antioxidant activity of cinnamon bark oil (cinnamomum zeylanicum l.) in Japanese quails under thermo neutral and heat stressed conditions. Kafkas Üniversitesi Veteriner Fakültesi Dergisi 19: 889-894.
SINGH, J., SETHI, A.P.S., SIKKA, S.S., CHATLI, M.K. and KUMAR, P. (2014) Effect of cinnamon (cinnamomum cassia) powder as a phytobiotic growth promoter in commercial broiler chickens. Animal Nutrition and Feed Technology 14: 471-479.
SU, L., YIN, J.J., CHARLES, D., ZHOU, K.Q., MOORE, J. and YU, L.L. (2007) Total phenolic contents, chelating capacities, and radical-scavenging properties of black peppercorn, nutmeg, rosehip, cinnamon and oregano leaf. Food Chemistry 100: 990-997.
SU, M.-J., CHEN, W.-P., LO, T.-Y. and WU, T.-S. (1999) Ionic mechanisms for the antiarrhythmic action of cinnamophilin in rat heart. Journal of Biomedical Science 6: 376-386.
SULAIMAN, S.A. (2013) .Extraction of essential oil from Cinnamomum zeylanicum by various methods as a perfume oil. Thesis for Degree of Bachelor of Engineering in Chemical engineering Faculty of Chemical & Natural Resources Engineering Universiti Malaysia Pahang. (Accessed on http://umpir.ump.edu.my/5808/1/CD6995.pdf).
TABATABAEI, S.M., BADALZADEH, R., MOHAMMADNEZHAD, G.R., BALAEI, R., TABATABAEI, S.M., BADALZADEH, R., MOHAMMADNEZHAD, G.R. and BALAEI, R. (2015) Effects of cinnamon extract on biochemical enzymes, tnf-α and nf-κb gene expression levels in liver of broiler chickens inoculated with escherichia coli. Pesquisa Veterinaria Brasileira 35: 781-787.
TAHER, M., FADZILAH ADIBAH, A.M. and MOHOMAD, R.S.A. (2006) Proanthocyanidin from Cinnamomum zeylanicum stimulates phosphorylation of insulin receptor in 3 T3-L1 adipocytes. Journal of Teknologi 44: 53-68.
THANKAMANI, C., SIVARAMAN, K., KANDIANNAN, K. and PETER, K. (1994) Agronomy of tree spices (clove, nutmeg, cinnamon and allspice) - A review. Journal of Spices & Aromatic Crops 2: 105-123.
TOGHYANI, M., TOGHYANI, M., GHEISARI, A., GHALAMKARI, G. and EGHBALSAIED, S. (2011) Evaluation of cinnamon and garlic as antibiotic growth promoter substitutions on performance, immune responses, serum biochemical and haematological parameters in broiler chicks. Livestock Science 138: 167-173.
TORKI, M., AKBARI, M. and KAVIANI, K. (2015) Single and combined effects of zinc and cinnamon essential oil in diet on productive performance, egg quality traits, and blood parameters of laying hens reared under cold stress condition. International Journal of Biometeorology 59: 1169-1177.
TUNG, Y.T., CHUA, M.T., WANG, S.Y. and CHANG, S.T. (2008) Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (cinnamomum osmophloeum) twigs. Bioresource Technology 99: 3908-3913.
UPADHYAYA, I., UPADHYAY, A., KOLLANOOR-JOHNY, A., MOOYOTTU, S., BASKARAN, S.A., YIN, H.B., SCHREIBER, D.T., KHAN, M.I., DARRE, M.J., CURTIS, P.A. and VENKITANARAYANAN, K. (2015) In-feed supplementation of trans-cinnamaldehyde reduces layer-chicken egg-borne transmission of salmonella enterica serovar enteritidis. Applied and Environmental Microbiology 81: 2985-2994.
VALERO, M. and SALMERON, M.C. (2003) Antibacterial activity of 11 essential oils against bacillus cereus in tyndallized carrot broth. International Journal of Food Microbiology 85: 73-81.
VANGALAPATI, M., SATYA, N.S., PRAKASH, D.V.S. and AVANIGADDA, S. (2012) A review on pharmacological activities and clinical effects of cinnamon species. Research Journal of Pharmaceutical Biological & Chemical Sciences 3: 653-663.
WIJESEKERA, R.O. (1977) Historical overview of the cinnamon industry. Critical Reviews in Food Science and Nutrition 10: 1.
YAP, P.S., LIM, S.H., HU, C.P. and YIAP, B.C. (2013) Combination of essential oils and antibiotics reduce antibiotic resistance in plasmid-conferred multidrug resistant bacteria. Phytomedicine 20: 710-713.
YU, S.M., WU, T.S. and TENG, C.M. (1994) Pharmacological characterization of cinnamophilin, a novel dual inhibitor of thromboxane synthase and thromboxane a2 receptor. British Journal of Pharmacology 111: 906-912.
ZHENG, X., GUO, Y., WANG, L., ZHANG, H., WANG, S., WANG, L., AN, L., ZHOU, X., LI, X. and YAO, C. (2015) Recovery profiles of T-cell subsets following low-dose total body irradiation and improvement with cinnamon. International Journal of Radiation Oncology* Biology* Physics 93: 1118-1126.
ZHOU, L., CHEN, Z.X. and CHEN, J.Y. (1995) Effect of wu lin powder and its ingredients on atrial natriuretic factor level in mice. Zhongguo Zhong Xi Yi Jie He Za Zhi 15: 36-37.
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