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The potential of antioxidant rich essential oils against avian coccidiosis

  • M. IDRIS (a1), R.Z. ABBAS (a2), S. MASOOD (a3), T. REHMAN (a1), U. FAROOQ (a1), W. BABAR (a1), R. HUSSAIN (a1), A. RAZA (a4) (a5) and U. RIAZ (a1)...

The poultry industry is currently facing a serious problem of controlling coccidiosis, owing to the development of drug resistance against commonly available anticoccidials. Furthermore, an increasing demand in the consumers for drug residue free poultry and poultry products has led to the development of alternative strategies for the treatment and control of avian coccidiosis. In response to the invasion of Eimeria species in coccidiosis, oxidative stress is created by host cellular response which imparts pathology to the host tissue besides damaging the parasite. Hence, in order to alleviate the damage caused by oxidative stress during coccidiosis, the use of essential oils (EOs) rich in antioxidant compounds is being considered as an appealing approach. However, results are very divergent and often not as satisfactory as expected. Essential oils, as natural products, obtained from aromatic plants have the potential to serve as an alternate to anticoccidials. The present work aims to review the current state of knowledge, informative collection of results obtained over the years and to attain a critical decision in aspects of the use of EOs as anticoccidials.

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R.Z. ABBAS , D.D. COLWELL and J. GILLEARD (2012a) Botanicals: An alternative approach for the control of avian coccidiosis. World's Poultry Science Journal 68: 203-215.

R.Z. ABBAS , Z. IQBAL , D. BLAKE , M.N. KHAN and M.K. SALEEMI (2011a) Anticoccidial drug resistance in fowl coccidia: the state of play revisited. World's Poultry Science Journal 67: 337-350.

A.M. ALI , SH.A. SEDDIEK and H.F. KHATER (2014) Effect of butyrate, clopidol and their combination on the performance of broilers infected with Eimeria maxima. British Poultry Science 55: 474-482 (DOI: 10.1080/00071668.2014.920488).

A.A. ALNASSAN , M. KOTSCH , A.A. SHEHATA , M. KRUGER , A. DAUGSCHIES and B. BANGOURA (2014) Necrotic enteritis in chickens development of a straightforward disease model system. Veterinary Records 174: 555.

M. ALP , M. MIDILLI , N. KOCABAGLI , H. YILMAZ , N. TURAN , A. GARGILI and N. ACAR (2012) The effects of dietary oregano essential oil on live performance, carcass yield, serum immunoglobulin G level, and oocyst count in broilers. Journal of Applied Poultry Research 21: 630-636.

A. ARCZEWSKA-WLOSEK and S. SWIATKIEWICZ (2013) Improved performance due to dietary supplementation with selected herbal extracts of broiler chickens infected with Eimeria spp . Journal of Animal and Feed Sciences 22: 257-263.

J.S. ARMSTRONG (2006) Mitochondrial membrane permeabilisation: the sine qua non for cell death. BioEssays 28: 253-260.

S. ATHANASIADOU , J. GITHIORI and I. KYRIAZAKIS (2007) Medicinal plants for helminth parasite control: Facts and fiction. Animal 1: 1392-1400.

F. BAKKALI , S. AVERBECK , D. AVERBECK and M. IDAOMAR (2008) Biological effects of essential oils - A review. Food and Chemical Toxicology 46: 446-475.

R. BARBEHENN , S. CHEEK , A. GASPERUT , E. LISTER and R. MABEN (2005) Phenolic compounds in red oak and sugar maple leaves have prooxidant activities in the midgut fluids of Malacosoma disstria and Orgyia leucostigma caterpillars . Journal of Chemical Ecology 31: 969-988.

E.K. BARBOUR , R.R. BRAGG , G. KARROUF , A. IYER , E. AZHAR , S. HARAKEH and T. KUMOSANI (2015) Control of eight predominant Eimeria spp. involved in economic coccidiosis of broiler chicken by a chemically characterised essential oil. Journal of Applied Microbiology 118: 583-591 (DOI: 10.1111/jam.12731).

D.P. BLAKE and F.M. TOMLEY (2014) Securing poultry production from the ever present Eimeria challenge. Trends in Parasitology 30: 12-19.

M. BOZKURT , N. AYSUL , K. KÜÇÜKYILMAZ , S. AYPAK , G. EGE , A.U. ÇATLI , H. AKŞIT , F. ÇÖVEN , K. SEYREK and M. ÇINAR (2014) Efficacy of in-feed preparations of an anticoccidial, multienzyme, prebiotic, probiotic, and herbal essential oil mixture in healthy and Eimeria spp.-infected broilers. Poultry Science 93: 389-399.

M. BOZKURT , I. GIANNENAS , K. KUCUKYILMAZ , E. CHRISTAKI and P. FLOROU-PANERI (2013) An update on approaches to controlling coccidia in poultry using botanical extracts. British Poultry Science 54: 713-727.

S. BURT (2004) Essential oils their antibacterial properties and potential applications in food-a review. The International Journal of Food Microbiology 94: 223-253.

H.D. CHAPMAN (2000) Practical use of vaccines for the control of coccidiosis in the chicken. World's Poultry Science Journal 56: 7-20.

H.D. CHAPMAN (2014) Milestones in avian coccidiosis research: A review. Poultry Science 93: 501-511.

H.D. CHAPMAN , T.K. JEFFERS and R.B. WILLIAMS (2010) Forty years of monensin for the control of coccidiosis in poultry. Poultry Science 89: 1788-1801.

E. CHRISTAKI , E. BONOS , I. GIANNENAS and P. FLOROU-PANERI (2012) Review: Aromatic plants as a source of bioactive compounds. Agriculture 2: 228-243.

E. CHRISTAKI , P. FLOROU-PANERI , I. GIANNENAS , M. PAPAZAHARIADOU , N. BOTSOGLOU and A.B. SPAIS (2004) Effect of a mixture of herbal extracts on broiler chickens infected with Eimeria tenella . Animal Research 53: 137-144.

M.A. DA SILVA , B.M.S. PESSOTTI , S.F. ZANINI , G.L. COLNAGO , M.R.A. RODRIGUES , L.C. NUNES , M.S. ZANINI and I.V.F. MARTINS (2009) Intestinal mucosa structure of broiler chickens infected experimentally with Eimeria tenella and treated with essential oil of oregano. Cienc Rural, Santa Maria 39: 1471-1477.

R.A. DALLOUL and H.S. LILLEHOJ (2006) Poultry coccidiosis: recent advancements in control measures and vaccine development. Expert Review of Vaccines 5: 143-163.

P.J. DELAQUIS , K. STANICH , B. GIRARD and G. MAZZA (2002) Antimicrobial activity of individual and mixed fractions of dill, cilantro, coriander and eucalyptus essential oils. The International Journal of Food Microbiology 74: 101-109.

H.J.D. DORMAN and S.G. DEANS (2000) Antimicrobial agents from plants: antibacterial activity of plant volatile oils. Journal of Applied Microbiology 88: 308-316.

N.V. GEORGIEVA , M. GABRASHANSKA , V. KOINARSKI and S. ERMIDOU-POLLET (2011a) Antioxidant status in Eimeria acervulina infected chickens after dietary selenium treatment. Trace Elements and Electrolytes 28: 42-48.

I. GIANNENAS , P. FLOROU-PANERI , M. PAPAZAHARIADOU , E. CHRISTAKI , N.A. BOTSOGLOU and A.B. SPAIS (2003) Effect of dietary supplementation with oregano essential oil on performance of broilers after experimental infection with Eimeria tenella . Archives of Animal Nutrition 57: 99-106.

H. GREATHEAD (2003) Plants and plant extracts for improving animal productivity. Proceedings of the Nutrition Society 62: 279-290.

M.E. HUME , S. CLEMENTE-HERNÁNDEZ and E.O. OVIEDO-RONDON (2006) Effects of feed additives and mixed Eimeria species infection on intestinal microbial ecology of broilers. Poultry Science 85: 2106-2111.

G. HUYGHEBAERT , R. DUCATELLE and F.V. IMMERSEEL (2011) Review: An update on alternatives to antimicrobial growth promoters for broilers. Veterinary Journal 187: 182-188.

D. JAMROZ , T. WERTELECKI , M. HOUSZKA and C. KAMEL (2006) Influence of diet type on the inclusion of plant origin active substances on morphological and histochemical characteristics of the stomach and jejunum walls in chicken. Journal of Animal Physiology and Animal Nutrition(Berl) 90: 255-268.

C. JULIANO , A. MATTANA and M. USAI (2000) Composition and in vitro antimicrobial activity of the essential oil of Thymus herba-barona Loisel growing wild in Sardinia. Journal of Essential Oil Research 12: 516-522.

H.F. KHATER (2014) Bioactivities of some essential oils against the camel nasal botfly, Cephalopina titillator . Parasitology Research 113: 593-605.

H.F. KHATER and D.F. KHATER (2009) Tropical medicine rounds; The insecticidal activity of four medicinal plants against the blowfly Lucilia sericata (Diptera: Calliphoridae). International Journal of Dermatology 48: 492-497.

H.F. KHATER , M.M. EL-SHORBAGY and S.A. SEDDIEK (2014) Lousicidal efficacy of camphor oil, d-phenothrin, and deltamethrin against the slender pigeon louse, Columbicola columbae . International Journal of Veterinary Science and Medicine 2: 7-13.

H.F. KHATER , A. HANAFY , A. ABDEL-MAGEED , M.Y. RAMADAN and R.S. EL-MADAWY (2011) Tropical medicine rounds; Control of the myiasis-producing fly, Lucilia sericata, with Egyptian essential oils. International Journal of Dermatology 50: 187-194.

H.F. KHATER , M.Y. RAMADAN and A.D.A. MAGEID (2013) In vitro control of the camel nasal botfly, Cephalopina titillator, with doramectin, lavender, camphor, and onion oils. Parasitology Research 112: 2503-2510.

K.W. LEE , H. EVERTS , H.J. KAPPERT , K.H. YEOM and A.C. BEYNEN (2003) Dietary carvacrol lowers body weight gain but improves feed conversion in female broiler chickens. Journal of Applied Poultry Research 12: 394-399.

Y.C. LIU , J.G. ZENG , B.O. CHEN and S.Z. YAO (2007) Investigation of phenolic constituents in Echinacea purpurea grown in China. Planta Medica 73: 1600-1605.

M. MACHADO , A.M. DINIS , L. SALGUEIRO , C. CAVALEIRO , J.B.A. CUSTODIO and M. DO CEU SOUSA (2010) Anti-Giardia activity of phenolic-rich essential oils: effects of Tymbra capitata, Origanum virens, Tymus zygis subsp. sylvestris, and Lippia graveolens on trophozoites growth, viability, adherence and ultrastructure. Parasitology Research 106: 1205-1215.

T.G. MCCLOUD (2010) High throughput extraction of plant, marine and fungal specimens for preservation of biologically active molecules-a review. Molecules 15: 4526-4563.

G. MILHAU , A. VALENTIN , F. BENOIT , M. MALLIE , J.M. BASTIDE , Y. PELISSIER and J.N. BESSIERE (1997) In vitro antimalarial activity of eight essential oils. Journal of Essential Oil Research 9: 329-333.

M. MOHITI-ASLI and M. GHANAATPARAST-RASHTI (2015) Dietary oregano essential oil alleviates experimentally induced coccidiosis in broilers. Preventive veterinary medicine 120: 195-202.

V. NAIDOO , L.J. MCGAW , S.P. BISSCHOP , N. DUNCAN and J.N. ELOFF (2008) The value of plant extracts with antioxidant activity in attenuating coccidiosis in broiler chickens. Veterinary Parasitology 153: 214-219.

E.O. OVIEDO-RONDON , M.E. HUME , C. HERNANDEZ and S. CLEMENTE-HERNANDEZ (2006a) Intestinal microbial ecology of broilers vaccinated and challenged with mixed Eimeria species, and supplemented with essential oil blends. Poultry Science 85: 854-860.

N. REISINGER , T. STEINER , S. NITSCH , G. SCHATZMAYR and T.J. APPLEGATE (2011) Effects of a blend of essential oils on broiler performance and intestinal morphology during coccidial vaccine exposure. Journal of Applied Poultry Research 20: 272-283.

A. REMMAL , S. ACHAHBAR , L. BOUDDINE , N. CHAMI and F. CHAMI (2011) In vitro destruction of Eimeria oocysts by essential oils. Veterinary Parasitology 182: 121-126.

G.H. RODRIGUES , E.A. KIMURA , V.J. PERES , A.S. COUTO , D.F.A. AQUINO and A.M. KATZIN (2004) Terpenes arrest parasitic development and inhibit biosynthesis of isoprenoids in Plasmodium falciparum . Antimicrobial Agents and Chemotherapy 48: 2502-2509.

M. RUSSO , G.C. GALLETTI , P. BOCCHINI and A. CARNACINI (1998) Essential oil chemical composition of wild populations of Italian oregano spice (Origanum vulgare ssp. hirtum (Link) letswaart): A preliminary evaluation of their use in chemotaxonomy by cluster analysis: 1. Inflorescences. Journal of Agricultural and Food Chemistry 46: 3741-3746.

A. TSINAS , I. GIANNENAS , C. VOIDAROU , A. TZORA and J. SKOUFOS (2011) Effects of oregano based dietary supplement on performance of broiler chickens experimentally infected with Eimeria acervulina and Eimeria maxima . Journal of Poultry Science 48: 194-200.

T. UEDA-NAKAMURA , R.R. MENDONCA-FILHO , J.A. MORGADO-DIAZ , P. KOREHISA , B. PRADO , D. APARICIO , D.S. ALVIANO , M.D.S. ROSA , A.H. LOPES , C.S. ALVIANO and C.V. NAKAMURA (2006) Antileishmanial activity of eugenol-rich essential oil from Ocimum gratissimum . Parasitology International 55: 99-105.

A.E. VERCESI , A.J. KOWALTOWSKI , M.T. GRIJALBA , A.R. MEINICKE and R.F. CASTILHO (1997) The role of reactive oxygen species in mitochondrial permeability transition. Bioscience Reports 17: 43-52.

G.C. WAGHORN and W.C. MCNABB (2003) Consequences of plant phenolic compounds for productivity and health of ruminants. Proceedings of the Nutrition Society 62: 383-92.

L. WALDENSTEDT (2003) Effect of vaccination against coccidiosis in combination with an antibacterial oregano (Origanum vulgare) compound in organic broiler production. Acta Agriculturae Scandinavica, Section A - Animal Science 53: 101-109.

R.J. WALLACE , W. OLESZEK , C. FRANZ , I. HAHN , K.H.C. BASER , A. MATHE and K. TEICHMANN (2010) Dietary plant bioactives for poultry health and productivity. British Poultry Science 51: 461-487.

R.B. WILLIAMS (1997) Laboratory tests of phenolic disinfectants as oocysticides against the chicken coccidium Eimeria tenella . Veterinary Records 141: 447-448.

Z. ZHAI , L. YI , L. WU , D.S. SENCHINA , E.S. WURTELE , P.A. MURPHY , M.L. KOHUT and J. CUNNIK (2007) Enhancement of innate and adaptive immune functions by multiple Echinacea species. Journal of Medicinal Food 10: 423-434.

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World's Poultry Science Journal
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