Hostname: page-component-8448b6f56d-mp689 Total loading time: 0 Render date: 2024-04-20T01:13:25.470Z Has data issue: false hasContentIssue false
  • English
  • Français

A Novel and Low-Cost Disposable Device for Phototherapy of Neonatal Jaundice

Published online by Cambridge University Press:  31 January 2011

Giovana R Ferreira ,
Cláudia K. B. de Vasconcelos ,
Mariana M Silva ,
Fabrício A dos Santos ,
Jorge G. Pires ,
André S Duarte ,
Andrea Gomes Campos Bianchi  and
Rodrigo Fernando Bianchi
Giovana R Ferreira
Affiliation:
giovanaribeiro_ufop@yahoo.com.br, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Cláudia K. B. de Vasconcelos
Affiliation:
ckbvasconcelos@iceb.ufop.br, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Mariana M Silva
Affiliation:
mms1985@uol.com.br, Universidade Federal de Ouro Preto, Departamento de Fisica, Ouro Preto, Minas Geraes, Brazil
Fabrício A dos Santos
Affiliation:
santosfrabricio@gmail.com, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Jorge G. Pires
Affiliation:
jorgeguerrapires@gmail.com, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
André S Duarte
Affiliation:
asdzin@gmail.com, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Andrea Gomes Campos Bianchi
Affiliation:
andrea@iceb.ufop.br, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Rodrigo Fernando Bianchi
Affiliation:
bianchi@iceb.ufop.br, Universidade Federal de Ouro Preto, LAPPEM - Departamento de Física, Ouro Preto, Brazil
Get access

Abstract

The present work details, to our knowledge, the first examination of the influence of blue-light radiation on the optical properties of organic luminescent films in attempting to develop an indicator dosimeter for phototherapy of neonatal jaundice. Jaundice is the most common problem encountered in newborns due to immature functioning in the liver. The operating principle of the device is based on the optical response of poly[2-methoxy-5-(2'-ethylhexyloxy)-p-phenylene (MEH-PPV) and tris(8-hydroxyquinolinato) aluminum (Alq3) materials dispersed in polystyrene (PS) matrix (denoted as PS/MEH-PPV/Alq3). It is observed a blue-shift on the photoluminescence of PS/MEH-PPV/Alq3 system from red to orange-yellow, and then to green as function of the blue-light radiation exposure time. The result is attributed to the spectral overlap between emission of Alq3 and absorption of MEH-PPV. The optical response of PS/MEH-PPV/Alq3 to radiation was investigated to design a low-cost (< US$ 0.05) “smart” sensor to represent easily the radiation dosage normally used in blue-light phototherapy. The basic idea behind this concept considers the sensor as a traffic light device, where red represents underdose and green the prescription dose or overdose, while orange-yellow suggests that radiation therapy is an ongoing process. This personal real-time radiation dosimeter appears here as a key requirement for successful development of innovations in effective management of the radiation dose planning before treatment of neonatal where control of dose absorption of infants is extremely important.

Keywords

sensorpolymerelectronic material
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1209: Symposia P/YY – Business and Safety Issues in the Commercialization of Nanotechnology , 2009 , 1209-P03-03
Copyright
Copyright © Materials Research Society 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Grossweiner, L. I. “The science of phototherapy: An introduction”, 1st Ed. (Springer, 2005).Google Scholar
2 Maisels, J.M. McDonagh, A. F. New Engl. Jour. Med 358, 920–928 (2008).Google Scholar
3 Vreman, H. J. Stevenson, D. K. Reader, S. D. Pediatric Res., 41, 185–187 (1997).Google Scholar
4 Tan, K. L. Acta Pediatr., 81, 870–874 (1992).Google Scholar
5 Tan, K. L. Jour. Pediatr., 16, 670–674 (1982).Google Scholar
6 Du, H. Fuh, R. A. Li, J. Corkan, A. Lindsey, J. S. Photochem. and Photobio., 68, 141–142 (1998).Google Scholar
7 Romagnoli, C. Marroco, G. Carolis, M. P. De, Jour. Pediatr., 112, 476–478 (1988).Google Scholar
8 McDonagh, A. F. Jour. Perinatol 21, Suppl 1: S7-S12 (2001).Google Scholar
9 Newman, T. B. Liljestrand, P. Escobar, G. J. Arch. Pediatr. Adolesc. Med 159, 113 (2005).Google Scholar
10 Ferreira, G. R. Vasconcelos, C. K. B. de, Bianchi, R. F. Med. Phys., 36, 642–644 (2009).Google Scholar
11 Vasconcelos, C. K. B. de, Bianchi, R. F. Sens. and Actuat. B: Chem., 143, 1, 30–34 (2009).Google Scholar
12 Ferreira, G. R. Vasconcelos, C. K. B. de, Schimitberger, T. Bianchi, R. F. Patent Pending (December 2009).Google Scholar
13 Martins, B. M. R. Carvalho, M. de, Moreira, M. E. L. Lopes, J. M. A. Journal de Pediatria, 83, 253–258 (2007).Google Scholar
14 Pope, M. Swenberg, C. E. “Electronic Processes in Organic Crystals and Polymers”, 1st Ed. (Oxford University Press 2002).Google Scholar
15 Bianchi, R. F. Balogh, D. T. Tirani, M. Faria, R. M. Irene, E. A. J. Polym. Sci., Part B: Polym. Phys., 42, 1033–1041 (2004).Google Scholar