Hostname: page-component-76fb5796d-x4r87 Total loading time: 0 Render date: 2024-04-25T20:56:20.147Z Has data issue: false hasContentIssue false
  • English
  • Français

Persistent enteral infections with adenovirus types 1 and 2 in infants: no evidence of reinfection

Published online by Cambridge University Press:  15 May 2009

T. Adrian ,
G. Schäfer ,
M. K. Cooney ,
J. P. Fox  and
R. Wigand
T. Adrian
Affiliation:
Department of Virology, University of the Saarland, D-6650 Homburg/Saar, FRG.
G. Schäfer
Affiliation:
Department of Virology, University of the Saarland, D-6650 Homburg/Saar, FRG.
M. K. Cooney
Affiliation:
Department of Pathobiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195, USA.
J. P. Fox
Affiliation:
Deceased. Formerly Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195, USA.
R. Wigand
Affiliation:
Department of Virology, University of the Saarland, D-6650 Homburg/Saar, FRG.
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Isolates of adenovirus types 1 and 2, obtained from 11 infants with prolonged faecal excretion (up to 515 days), were compared by DNA restriction analysis with seven standard endonucleases which recognize hexanucleotides and two additional endonucleases which recognize tetranucleotides. In all instances identical genome types were identified in isolates obtained early and late after infection. Our interpretation of these data is that a chronic persistent infection occurred in these children. and not a reinfection with the same serotype.

Type
Research Article
Information
Epidemiology & Infection , Volume 101 , Issue 3 , December 1988 , pp. 503 - 509
Copyright
Copyright © Cambridge University Press 1988

References

REFERENCES

Adrian, TH., Best, B. & Wigand, R. (1985). A proposal for naming adenovirus genome types. exemplified by adenovirus type 6. Journal of General Virology 66, 2685–2691.CrossRefGoogle ScholarPubMed
Adrian, TH., Wadell, G., Hierholzer, J. C. & Wigand, R. (1986). DNA restriction analysis of adenovirus prototypes 1 to 41. Archives of Virology 91, 277–290.CrossRefGoogle ScholarPubMed
Brandt, C. D., Kim, H. W., Jeffries, B. C., Pyles, G., Christmas, E. E., Reid, J. L., Chanock, R. M. & Parrott, R. H. (1972). Infections in 18000 infants and children in a controlled study of respiratory tract disease. II. Variation of adenovirus infections by year and season. American Journal of Epidemiology 95, 218–227.Google Scholar
Brandt, C. F., Wasserman, F. E. & Fox, J. P. (1966). The virus watch program. IV. Recovery and comparison of two serological variants of adenovirus type 5. Proceedings of the Society for Experimental Biology and Medicine 123, 513–518.Google Scholar
Fox, J. P., Brandt, C. D., Wasserman, F. E., Hall, C. E., Spigland, I., Kogon, A. & Elveback, L. R. (1969). The virus watch program: a continuing surveillance of viral infections in metropolitan New York families. VI. Observations of adenovirus infections: virus excretion patterns, antibody response, efficiency of surveillance, patterns of infection, and relation to illness. American Journal of Epidemiology 89, 25–50.CrossRefGoogle Scholar
Fox, J. P., Hall, C. E. & Cooney, M. K. (1977). The Seattle virus watch. VII. Observations of adenovirus infections. American Journal of Epidemiology 105, 362–386.Google Scholar
Monto, A. S., Napier, J. A. & Metzner, H. L. (1971). The Tecumseh study of respiratory illness. I. Plan of study and acute respiratory disease. American Journal of Epidemiology 94, 269–279.Google Scholar
Pacini, D. L., Collier, A. M. & Henderson, F. W. (1987). Adenovirus infections and respiratory illnesses in children in group day care. Journal of Infectious Diseases 156, 920–927.Google Scholar
Schmitz, H., Wigand, R. & Heinrich, W. (1983). Worldwide epidemiology of human adenovirus infections. American Journal of Epidemiology 117, 455–466.CrossRefGoogle ScholarPubMed
Wadell, G., Varsanyi, T., Lord, A. & Sutton, R. N. P. (1980). Epidemic outbreaks of adenovirus 7 with special reference to the pathogenicity of adenovirus genome type 7 b. American Journal of Epidemiology 112, 619–628.CrossRefGoogle Scholar
Wasserman, R., August, C. S. & Plotkin, S. A. (1988). Viral infections in pediatric bone marrow transplant patients. Pediatric Infectious Diseases 7, 109–115.CrossRefGoogle ScholarPubMed
Wigand, R. (1978). Re: ‘The Seattle virus watch. VII. Observations of adenovirus infections’ by Fox J. P., Hall C. E. & Cooney M. K. American Journal of Epidemiology 107, 352.CrossRefGoogle Scholar
Wigand, R. & Adrian, TH. (1986) (ed. Doerfler, W.), pp. 409–441. Boston. Dordrecht. Lancaster: Martinus Nijhoff.Google Scholar