Hostname: page-component-8448b6f56d-jr42d Total loading time: 0 Render date: 2024-04-20T02:33:09.942Z Has data issue: false hasContentIssue false
  • English
  • Français

Association of production factors with milk IgA and IgM concentrations in normal lactating cows

Published online by Cambridge University Press:  08 September 2010

Shengguo Zhao ,
Chungang Zhang ,
Jiaqi Wang ,
Dengpan Bu ,
Guanglei Liu  and
Lingyun Zhou
Shengguo Zhao
Affiliation:
State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, P. R. China
Chungang Zhang
Affiliation:
State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, P. R. China
Jiaqi Wang*
Affiliation:
State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, P. R. China
Dengpan Bu
Affiliation:
State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, P. R. China
Guanglei Liu
Affiliation:
State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, P. R. China
Lingyun Zhou
Affiliation:
State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, P. R. China
*
†For correspondence; e-mail: jqwangcaas@gmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Concentrations of IgA and IgM in milk from normal lactating cows were measured to determine whether they were affected by lactation number, lactation stage, daily milk production, milk composition and somatic cell score (SCS). A total of 284 Chinese Holstein cows showing no signs of mastitis were selected from more than 1600 cows from one farm. Concentrations of IgA and IgM in normal milk were determined by ELISA. Results revealed that average milk IgA and IgM concentrations were 235±11 and 32±3 μg/ml, respectively. IgA and IgM concentrations in milk were found to have an association with lactation number, stage of lactation, daily milk production and SCS. Both SCS and daily milk production were found to be strong significant (P<0·01) direct factors correlating to IgA concentration. Stage of lactation and SCS were found to be strong significant (P<0·01) direct factors correlating to IgM concentration.

Keywords

IgAIgMproduction parametersmilk composition
Type
Research Article
Information
Journal of Dairy Research , Volume 77 , Issue 4 , November 2010 , pp. 481 - 486
Copyright
Copyright © Proprietors of Journal of Dairy Research 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Butler, JE 1986 Biochemistry and biology of ruminant immunoglobulins. Progress in Veterinary Microbiology and Immunology 2 51–53Google ScholarPubMed
Butler, JE 1994 Passive immunity and immunoglobulin diversity. In Indigenous Antimicrobial Agents of Milk—Recent Developments. IDF Special Issue 9404, pp. 14–50Google Scholar
Caffin, JP, Poutrel, B & Rainard, P 1983 Physiological and pathological factors influencing bovine immunoglobulin G1 concentration in milk. Journal of Dairy Science 66 2161–2166Google Scholar
De Groot, N, Van Kuik-Romeijn, P, Lee, SH & De Boer, HA 2000 Increased immunoglobulin A levels in milk by over-expressing the murine polymeric immunoglobulin receptor gene in the mammary gland epithelial cells of transgenic mice. Journal of Immunology 101 218–214CrossRefGoogle ScholarPubMed
Devery-Pocius, JE & Larson, BL 1982 Age and previous lactations as factors in the amount of bovine colostral immunoglobulins. Journal of Dairy Science 66 221–226Google Scholar
Hagiwara, S, Kawai, K, Anri, A & Nagahata, H 2003 Lactoferrin concentrations in milk from normal and subclinical mastitic cows. Journal of Veterinary Medical Science 65 319–323CrossRefGoogle ScholarPubMed
Kishimoto, S, Tomino, S, Kotegawa, S, Saito, T, Kuroki, M, Mitsuya, H & Hisanitsu, S 1978 Age related changes in the subsets and functions of human T lymphocytes. Journal of Immunology 121 1773–1780Google Scholar
Korhonen, H, Marnila, P & Gill, HS 2000 Milk immunoglobulins and complement factors. British Journal of Nutrition 84 75–80CrossRefGoogle ScholarPubMed
Kumura, BH, Sone, T, Shimazaki, K & Kobayashi, E 2000 Sequence analysis of porcine polymeric immunoglobulin receptor from mammary epithelial cells present in colostrum. Journal of Dairy Research 67 631–636CrossRefGoogle ScholarPubMed
Larson, BL, Heary, HL, Devery, JR & Devery, JE 1980 Immunoglobulin production and transport by the mammary gland. Journal of Dairy Science 63 665–671CrossRefGoogle ScholarPubMed
Lilius, EM & Marnila, P 2001 The role of colostral antibodies in prevention of microbial infections. Current Opinion in Infectious Diseases 14 295–300Google Scholar
Lindmark-Månsson, H, Bränninga, C, Aldéna, G & Paulssonb, M 2006 Relationship between somatic cell count, individual leukocyte populations and milk components in bovine udder quarter milk. International Dairy Journal 16 717–727CrossRefGoogle Scholar
Liu, GL, Wang, JQ, Bu, DP, Cheng, JB, Zhang, CG, Wei, HY, Zhou, LY, Zhou, ZF, Hu, H & Dong, XL 2009 Factors affecting the transfer of immunoglobulin G1 into the milk of Holstein cows. Veterinary Journal 182 79–85CrossRefGoogle ScholarPubMed
Marnila, P & Korhonen, H 2002 Immunoglobulins. In: Encyclopedia of Dairy Science (Roginski, H, Fuquay, JW & Fox, PF) pp. 1950–1956. London, UK: Academic PressGoogle Scholar
Mazengera, KE, Kennedy, BW, Burnside, EB, Wilkie, BN & Burton, JH 1985 Genetic parameters of bovine serum immunoglobulins. Journal Dairy Science 68 2309–2314CrossRefGoogle ScholarPubMed
McFadden, TB, Besser, TE & Barrington, GM 1997 Regulation of immunoglobulin transfer into mammary secretions of ruminants. In: Milk Composition, Production and Biotechnology (Welch, RAS, Burns, DJW, Davis, SR & Popay, AL ) pp. 132–152. Wallingford, UK: CTAB InternationalGoogle Scholar
Mestecky, J, Russell, MW & Elson, CO 1999 Intestinal IgA: novel views on its function in the defense of the largest mucosal surface. Gut 44 2–5CrossRefGoogle ScholarPubMed
Mostov, KE & Kaetzel, SS 1999 Immunoglobulin transport and the polymeric immunoglobulin receptor. In: Mocosal Immunology (Ogra, PL, Mestecky, J, Lamn, ME, Strober, W, Bienenstock, J & McGhee, JR) pp. 181–211. San Diego CA, USA: Academic PressGoogle Scholar
Norderhaug, IN, Johansen, FE, Schjerven, H & Brandtzaeg, P 1999 Regulation of the formation and external transport of secretory immunoglobulins. Critical Reviews in Immunology 19 481–508Google Scholar
Oyeniyi, OO & Hunter, AG 1978 Colostral constituents including immunoglobulins in the first three milkings postpartum. Journal of Dairy Science 61 44–48CrossRefGoogle ScholarPubMed
Philipsson, J, Ral, G & Berglund, B 1995 Somatic cell count as a selection criterion for mastitis resistance in dairy cow. Livestock Production Science 41 195–200CrossRefGoogle Scholar
Schallibaum, M 2001 Impact of SCC on the quality of fluid milk and cheese. 40th Annual Meeting, National Mastitis Council, Madison WI, USA. pp. 38–46Google Scholar
Sharif, A & Muhammad, G 2008 Somatic cell count as an indicator of udder health status undermodern dairy production: a review. Pakistan Veterinary Journal 28 194–200Google Scholar
Shook, GE 1982 Approaches to summarizing somatic cell count which improve interpretability. In: Proceedings 21st Annual Meeting of the National Mastitis Council, Arlington VA, USA. National Mastitis Council, Arlington VA, pp. 150–166Google Scholar
Suriyasathaporn, W, Schukken, YH, Nielen, M & Brand, A 2000 Low somatic cell count: a risk factor for subsequent clinical mastitis in a dairy herd. Journal of Dairy Science 83 1248–1255Google Scholar
West, KL, Oftedal, OT, Carpenter, JR, Krames, BJ, Campbell, M & Sweeney, JC 2007 Effect of lactation stage and concurrent pregnancy on milk composition in the bottlenose dolphin. Journal of Zoology 273 1–13Google Scholar
Williams, MR, Spooner, RL & Thomas, LH 1975 Quantitative studies on bovine immunoglobulins. Veterinary Record 96 81–84Google Scholar