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18FDG-PET metabolic response of non-small-cell lung cancer to chemoradiotherapy with long-term follow-up

Published online by Cambridge University Press:  11 October 2017

Federico Ampil ,
Gloria Caldito  and
Troy Richards
Federico Ampil*
Affiliation:
Department of Radiology/Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA
Gloria Caldito
Affiliation:
Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA
Troy Richards
Affiliation:
Department of Radiology/Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA
*
Correspondence to: Federico Ampil, Department of Radiology/Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71103, USA. E-mail: fampil@lsuhsc.edu
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Abstract

Aim

18Fluorodeoxyglucose-positron emission tomography (FDG-PET) can indicate the presence or absence of non-small-cell lung cancer (NSCLC) after treatment. We present a description of the FDG-PET results following the contemporary management of locally advanced NSCLC including long-term outcomes.

Methodology

The study participants were eight long-term survivors with metabolic tumour response (MTR) shown on FDG-PET following chemoradiotherapy for locally advanced stage NSCLC between June 2005 and April 2009.

Results

After therapy, MTR was complete in five patients; four subjects were free of cancer, and one patient experienced progression of disease at the time of last follow-up. Of the three individuals with incomplete MTRs, distant metastases developed in two patients, and one subject remained disease-free. Long-term survival ranged from 37 to 75 months.

Conclusion

Although the number of cases is small, our observations confirm the diagnostic role of FDG-PET as well as its value for predicting prognosis in the clinical practice of oncology.

Keywords

chemoradiotherapyFDG-PET imaginglung cancer
Type
Original Articles
Information
Journal of Radiotherapy in Practice , Volume 17 , Issue 1 , March 2018 , pp. 131 - 134
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Copyright
© Cambridge University Press 2017 

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