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A BIOLOGICAL PROCESS SUBJECT TO NONCOMPETITIVE SUBSTRATE INHIBITION IN A GENERALIZED FLOW REACTOR

Part of: Physiological, cellular and medical topics

Published online by Cambridge University Press:  26 July 2013

M. I. NELSON ,
T. NICHOLLS  and
N. HAMZAH
M. I. NELSON*
Affiliation:
School of Mathematics and Applied Statistics, University of Wollongong, Wollongong, NSW 2522, Australia
T. NICHOLLS
Affiliation:
School of Mathematics and Applied Statistics, University of Wollongong, Wollongong, NSW 2522, Australia
N. HAMZAH
Affiliation:
Department of Mathematics, Faculty of Science, Universiti Brunei Darussalam, Brunei Darussalam
*
✉nelsonm@member.ams.org
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Abstract

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We analyse the steady-state operation of a continuous flow bioreactor in which the biochemical reaction is governed by noncompetitive substrate inhibition (Andrews kinetics). A generalized reactor model is used in which the well-stirred bioreactor and the idealized membrane bioreactor are special cases. As generic properties of systems subject to substrate inhibition have been obtained by other authors, we discuss reaction engineering features specific to Andrews kinetics.

Keywords

bioreactorkineticsstirred tanksubstrate inhibition

MSC classification

Secondary: 92C45: Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.)
Type
Research Article
Information
The ANZIAM Journal , Volume 54 , Issue 4 , April 2013 , pp. 273 - 290
Copyright
Copyright ©2013 Australian Mathematical Society 

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