This study assesses the pattern of occurrence of a generalist species, the Eurasian badger Meles meles, in forest fragments located in agricultural landscapes of central Spain with a coarse-grained pattern of fragmentation (<20% forest cover in the landscape). Four forest regions (n = 139 forest fragments) were sampled. Badger presence/absence in forest fragments was studied in relation to: forest size, isolation and vegetation structure. Badgers were tested to see if, despite their habitat generalism, they were negatively affected by forest fragmentation in this type of fragmented landscape. Results indicated a strong and significant effect of fragment size on badger occurrence (presence was rare in forest fragments <100 ha) and an important effect of isolation at a local scale. The response of badgers to forest fragmentation in Spain is quite different to the response in other European landscapes. In Spain, badgers cope with a divided coarse-grained landscape where suitable habitats are embedded in a largely unsuitable matrix (cereal croplands). In contrast, in Britain or central Europe, badgers may be benefited by forest clearances in a heterogeneous but non-divided landscape where small woodlots are separated by a matrix of good quality (mainly pastures) and fragmentation produces fine-grained mosaic landscapes where food and den sites are simultaneously enhanced. Species' response to forest fragmentation may strongly depend on the pattern of fragmentation and, in coarse-grained fragmented landscapes, generalist species may be affected in the same way as specialist ones.