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Redistribution of abdominal fat after a period of food restriction in rats is related to the type of dietary fat

Published online by Cambridge University Press:  09 March 2007

Federico Soriguer ,
Felisa Moreno ,
Gemma Rojo-Martínez ,
Fernando Cardona ,
Francisco Tinahones ,
Juan M. Gómez-Zumaquero ,
Eduardo García-Fuentes  and
Sonsoles Morcillo
Federico Soriguer*
Affiliation:
Endocrinology and Nutrition Service, Clinical and Experimental Investigation Unit, Civil Hospital, Carlos Haya Hospital Complex, Pza. del Hospital Civil /, 29009-Málaga, Spain
Felisa Moreno
Affiliation:
Endocrinology and Nutrition Service, Clinical and Experimental Investigation Unit, Civil Hospital, Carlos Haya Hospital Complex, Pza. del Hospital Civil /, 29009-Málaga, Spain
Gemma Rojo-Martínez
Affiliation:
Endocrinology and Nutrition Service, Clinical and Experimental Investigation Unit, Civil Hospital, Carlos Haya Hospital Complex, Pza. del Hospital Civil /, 29009-Málaga, Spain
Fernando Cardona
Affiliation:
Endocrinology and Nutrition Service, Clinical and Experimental Investigation Unit, Civil Hospital, Carlos Haya Hospital Complex, Pza. del Hospital Civil /, 29009-Málaga, Spain
Francisco Tinahones
Affiliation:
Endocrinology and Nutrition Service, Clinical and Experimental Investigation Unit, Civil Hospital, Carlos Haya Hospital Complex, Pza. del Hospital Civil /, 29009-Málaga, Spain
Juan M. Gómez-Zumaquero
Affiliation:
Endocrinology and Nutrition Service, Clinical and Experimental Investigation Unit, Civil Hospital, Carlos Haya Hospital Complex, Pza. del Hospital Civil /, 29009-Málaga, Spain
Eduardo García-Fuentes
Affiliation:
Endocrinology and Nutrition Service, Clinical and Experimental Investigation Unit, Civil Hospital, Carlos Haya Hospital Complex, Pza. del Hospital Civil /, 29009-Málaga, Spain
Sonsoles Morcillo
Affiliation:
Endocrinology and Nutrition Service, Clinical and Experimental Investigation Unit, Civil Hospital, Carlos Haya Hospital Complex, Pza. del Hospital Civil /, 29009-Málaga, Spain
*
*Corresponding Author: Dr Federico Soriguer, fax +34 952 286 704, email soriguer@hch.sas.cica.es
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Abstract

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The aim of the present experiment was to test the hypothesis that during refeeding a redistribution of intra-abdominal fat takes place and that both the recovery of weight and the redistribution of intra-abdominal fat are related to the type of dietary fat. The experimental study was carried out using male Sprague–Dawley rats. Three groups of animals were fed diets with three different fatty acid profiles. Each group contained two branches, one fed normally and the other fed initially with a 50 % energy reduction followed by refeeding ad libitum with the same isoenergetic diet as the control branch, giving a total of six treatments. Measurements were made of the final and incremental weight of the rat, weight of the intra-abdominal adipose tissue (total intra-abdominal, epididymal, omental and retroperitoneal adipose tissue weight), and feed efficacy (weight incremen/etabolizable energy intake). Carcass, epididymal, omental, and muscle lipid contents, carcass protein and energy density were also measured. The results revealed that diets rich in fish oil or olive oil increase catch-up growth more than diets rich in saturated fats. During refeeding the lipid content in the adipose tissue increases while that of muscle tissue decreases. A diet rich in saturated fats induces a relative increase in the amount of intra-abdominal adipose tissue. The lipid content in adipose and muscle tissues and the distribution of intra-abdominal fat can all be modified by the type of dietary fat.

Keywords

RatDietary fatty acidsFat redistribution
Type
Research Article
Information
British Journal of Nutrition , Volume 89 , Issue 1 , January 2003 , pp. 115 - 122
Copyright
Copyright © The Nutrition Society 2003

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