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Potassium supplementation, serum immunoreactive insulin concentrations and glucose tolerance in protein-energy malnutrition

Published online by Cambridge University Press:  25 March 2008

M. D. Mann ,
Dorothy J. Becker ,
B. L. Pimstone  and
J. D. L. Hansen
M. D. Mann
Affiliation:
Departments of Child Health and Medicine, University of Cape Town Medical School, Observatory, Cape Town, South Africa
Dorothy J. Becker
Affiliation:
Departments of Child Health and Medicine, University of Cape Town Medical School, Observatory, Cape Town, South Africa
B. L. Pimstone
Affiliation:
Departments of Child Health and Medicine, University of Cape Town Medical School, Observatory, Cape Town, South Africa
J. D. L. Hansen
Affiliation:
Departments of Child Health and Medicine, University of Cape Town Medical School, Observatory, Cape Town, South Africa
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Abstract

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1. The serum immunoreactive insulin (IRI) concentrations, and glucose disappearance rate-constants after intravenous glucose administration were measured on admission and during recovery in children suffering from protein-energy malnutrition (PEM).

2. A high potassium intake resulted in a considerable increase in the serum IRI levels early in the treatment period. There was a definite relationship between potassium depletion and many measurements of insulin secretion.

3. The results are consistent with the hypothesis that impaired insulin release in children suffering from PEM is partly the result of potassium depletion.

Type
Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 33 , Issue 1 , January 1975 , pp. 55 - 61
Copyright
Copyright © The Nutrition Society 1975

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