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Neuropsychiatric illness and neuropathological findings in a case of Klinefelter's syndrome

Published online by Cambridge University Press:  09 July 2009

A. Jablensky ,
I. Janota  and
Michael Shepherd
A. Jablensky
Affiliation:
Institute of Psychiatry and the Bethlem Royal and Maudsley Hospital, London S.E.5
I. Janota
Affiliation:
Institute of Psychiatry and the Bethlem Royal and Maudsley Hospital, London S.E.5
Michael Shepherd
Affiliation:
Institute of Psychiatry and the Bethlem Royal and Maudsley Hospital, London S.E.5
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Summary

A case of Klinefelter's syndrome with XXY karyotype and a dementing neuropsychiatric illness associated with a diffuse degeneration of the deep cerebral white matter and adrenal cortical atrophy is presented. The possible relationships between genetic abnormalities and disordered function and structure of the brain are discussed in the light of the clinical and pathological observations.

Type
Research Article
Information
Psychological Medicine , Volume 1 , Issue 1 , November 1970 , pp. 18 - 29
Copyright
Copyright © Cambridge University Press 1970

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References

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