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Treatment of hereditary haemorrhagic telangiectasia by the pulsed dye laser

Published online by Cambridge University Press:  29 June 2007

P. G. Harries ,
M. J. Brockbank ,
P. G. Shakespeare  and
J. A. S. Carruth
P. G. Harries*
Affiliation:
Department of Otolaryngology, Salisbury Healthcare NHS Trust, Salisbury District Hospital, Salisbury, UK
M. J. Brockbank
Affiliation:
Department of Otolaryngology, Salisbury Healthcare NHS Trust, Salisbury District Hospital, Salisbury, UK
P. G. Shakespeare
Affiliation:
Department of Laing Laboratory, Salisbury Healthcare NHS Trust, Salisbury District Hospital, Salisbury, UK
J. A. S. Carruth
Affiliation:
Department of Laser Unit, Salisbury Healthcare NHS Trust, Salisbury District Hospital, Salisbury, UK
*
Address for correspondence: Mr. P. G. Harries, The Coach House, Mill Road, Slindon Common, Arundel, West Sussex BN18 OLY
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Abstract

Hereditary haemorrhagic telangiectasia (Osler-Weber-Rendu syndrome, Osier's disease) is an inherited abnormality of the vasculature characterized by abnormal subepithelial vessels. Treatment has included repeated intranasal cautery, intra-arterial embolization and arterial ligation.

Treatment has included repeated intranasal cautery, intra-arterial embolization and arterial ligation. Historically, the operation of septodermoplasty and the use of systemic/topical oestrogens have been the most effective and lasting treatments, but over time the telangiectasias recur. There is increasing interest in the use of a variety of lasers for intranasal photocoagulation.

A report of nine patients suffering from hereditary haemorrhagic telangiectasia who have undergone laser treatment with the Chromos pulsed dye laser is presented. This laser produces light energy at a wavelength of 585 nm and causes localized thermal damage to the blood vessel wall.

Initially, no patient saw an improvement in their symptoms, but following an average of approximately three courses of treatment, all have reported a measurable reduction in the number of epistaxes suffered.

Although no treatment completely resolves the epistaxis associated with this condition, we have found the pulsed dye laser to be effective at treating telangiectasias within the anterior nasal cavity.

Keywords

Telangiectasia, hereditary haemorrhagicLaser surgery
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 111 , Issue 11 , November 1997 , pp. 1038 - 1041
Copyright
Copyright © JLO (1984) Limited 1997

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