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Non-Hodgkin's lymphoma of the maxillary sinus in a patient with acquired immunodeficiency syndrome

Published online by Cambridge University Press:  29 June 2007

Antonio Del Forno ,
Cosmo Del Borgo ,
Adriana Turriziani ,
Fabrizio Ottaviani ,
Andrea Antinori  and
Massimo Fantoni
Antonio Del Forno
Affiliation:
Departments of Infectious Diseases, Catholic University, Rome, Italy.
Cosmo Del Borgo
Affiliation:
Departments of Infectious Diseases, Catholic University, Rome, Italy.
Adriana Turriziani
Affiliation:
Departments of Radiotherapy, Catholic University, Rome, Italy.
Fabrizio Ottaviani
Affiliation:
Departments of Otolaryngology, Catholic University, Rome, Italy.
Andrea Antinori
Affiliation:
Departments of Infectious Diseases, Catholic University, Rome, Italy.
Massimo Fantoni*
Affiliation:
Departments of Infectious Diseases, Catholic University, Rome, Italy.
*
Address for correspondence: Massimo Fantoni, M.D., Department of Infectious Diseases, Catholic University, L.go Francesco Vito 1, 00168 Rome, Italy.
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Abstract

Non-Hodgkin's lymphoma (NHL) is one of the most common malignancies in patients infected with human immunodeficiency virus (HIV); it occurs 25–60 times more frequently in HIV-infected patients than in the general population. This neoplasm in acquired immunodeficiency syndrome (AIDS) patients is a highly aggressive tumour with a poor prognosis and tends to develop in extranodal sites, such as the central nervous system, digestive tract and bone marrow. NHL involving the paranasal sinuses is rare in HIV-infected patients, and is likely to be confused clinically and radiographically with sinusitis; moreover, its optimal treatment is currently uncertain.

We present a case of NHL involving the left maxillary sinus in a patient with AIDS. The patient was treated with systemic chemotherapy (low dose-CHOP), but the malignancy did not respond. Subsequently, he was treated with local maxillary sinus irradiation which resulted in partial regression of the neoplasm and in decrease of local symptoms.

Keywords

HIVLymphoma, non-Hodgkin's
Type
Oncology in Focus
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 10 , October 1998 , pp. 982 - 985
Copyright
Copyright © JLO (1984) Limited 1998

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References

Bermudez, M. A., Grant, K. M., Rodvien, R., Mendes, F. (1989) Non-Hodgkin's lymphoma in a population with or at risk for acquired immunodeficiency syndrome: indications for intensive chemotherapy. American Journal of Medicine 86: 71–76.CrossRefGoogle ScholarPubMed
Cleary, K. R., Batsakis, J. G. (1994) Pathology consultation. Sinonasal lymphomas. Annals of Otology, Rhinology and Laryngology 103: 911–914.Google Scholar
Desai, U. R., Peyman, G. A., Blinder, K. J., Alturki, W. A., Paris, C. L., Nelson, N. C. Jr. (1992) Orbital extension of sinus lymphoma in AIDS patient. Japanese Journal of Ophthalmology 36: 205–214.Google Scholar
Font, R. L., Laucirica, R., Patrinely, J. R. (1993) Immunoblastic B-cell malignant lymphoma involving the orbit and maxillary sinus in a patient with acquired immune deficiency syndrome. Ophthalmology 100: 966–970.Google Scholar
Goldstein, J., Rubin, J., Becker, N., Moser, F., Silverstein, M., Davis, L. (1991) Lymphoma of the maxillary sinus in a patient infected with human immunodeficiency virus type 1. Head and Neck 13: 355–358.CrossRefGoogle Scholar
Hamilton-Dutoit, S. J., Pallesen, G., Karkov, J., Skinhøj, P., Franzmann, M. B., Pedersen, C. (1989) Identification of EBV-DNA in tumour cells of AIDS-related lymphomas by in-situ hybridization. Lancet 1: 554–555.CrossRefGoogle Scholar
loachim, H. L., Dorsett, B., Cronin, W., Maya, M., Wahl, S. (1991) Acquired inununodeficiency syndrome-associated lymphomas: clinical, pathologic, immunologic, and viral characteristics of 111 cases. Human Pathology 22: 659–673.Google Scholar
Langford, A., Dienemann, D., Schurman, D., Pohle, H. D., Pauli, G., Stein, H., Reichart, P. (1991) Oral manifestations of AIDS-associated non-Hodgkin's lymphomas. International Journal of Oral and Maxillofacial Surgery 20: 136–141.Google Scholar
Leess, F. R., Kessler, D. J., Mickel, R. A. (1987) Non Hodgkin's lymphoma of the head and neck in patients with AIDS. Archives of Otolaryngology-Head and Neck Surgery 113: 1104–1106.Google Scholar
Levine, A. M. (1987) Non-Hodgkin's lymphomas and other malignancies in the acquired immunodeficiency syndrome. Seminars in Oncology 14 (Suppl 3): 34–39.Google Scholar
Levine, A. M., Wernz, J. C., Kaplan, L., Rodman, N., Cohen, P., Metroka, C., Bennett, J. M., Rarick, M. U., Walsh, C., Kahn, J., Miles, S., Ehmann, W. C., Feinberg, J., Nathwam, B., Gill, P. S., Mitsuyasu, R. (1991) Low dose chemotherapy with central nervous system prophylaxis and azidothymidine maintenance in AIDS-related lymphoma: a prospective multi-institutional trial. Journal of the American Medical Association 266: 84–88.Google Scholar
Pomilla, P. V., Morris, A. B., Jaworek, A. (1995) Sinonasal non-Hodgkin's lymphoma in patients infected with human immunodeficiency virus: report of three cases and review. Clinical Infectious Diseases 21: 137–149.Google Scholar
Quivey, J. M., Berson, A., Wara, W. W. (1989) The role of radiotherapy in the treatment of AIDS related non-Hodgkin's lymphoma (NHL). Proceedings of the Annual Meeting of the American Society of Clinical Oncology 8: 6 (abstr 22).Google Scholar
Rosenthal, J., Katz, R., DuBois, D. B., Morrissey, A., Machicao, A. (1992) Chrome maxillary sinusitis associated with the mushroom Schizophyllum commune in a patient with AIDS. Clinical Infectious Diseases 14: 46–48.CrossRefGoogle Scholar
Rubin, M. M., Sanfilippo, R. J. (1992) Lymphoma of the paranasal sinuses presenting as cavernous sinus syndrome. Journal of Oral and Maxillofacial Surgery 50: 749–751.Google Scholar
Schoem, S. R., Morton, A. L. (1990) Paranasal sinus Burkitt's lymphoma in a human immunodeficiency virus (HIV) positive male. Ear, Nose and Throat Journal 69: 844–846.Google Scholar
Shapiro, A. L., Shechtam, F. G., Guida, R. A., Kimmelman, C. P. (1992) Head and neck lymphoma in patients with the acquired immune deficiency syndrome. Otolaryngology – Head and Neck Surgery 106: 258–260.Google Scholar
Shiramizu, B., Herndier, B., Meeker, T., Kaplan, L., McGrath, M. (1992) Molecular and immunophenotypic characterization of AIDS-associated, Epstein-Barr virus-negative, polyclonal lymphoma. Journal of Clinical Oncology 10: 383–389.Google Scholar
The non-Hodgkin's lymphoma Pathologic Classification Project (1982) National Cancer Institute-sponsored study of classifications of non-Hodgkin's lymphomas. Summary and description of a working formulation for clinical usage. Cancer 49: 2112–2135.Google Scholar
Yang, H., Jayaram, S. (1993) Ptosis and headache in an i.v. drug abuser. Hospital Practice 28: 18–20.CrossRefGoogle Scholar