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Dynamic flow imaging using 320-detector row CT and motion coherence analysis in coronary aneurysms associated with Kawasaki disease

Published online by Cambridge University Press:  14 December 2017

Yamato Shimomiya ,
Michinobu Nagao ,
Yuzo Yamasaki ,
Takashi Shirasaka ,
Masatoshi Kondo ,
Tsukasa Kojima ,
Akihiro Nishie ,
Kenichiro Yamamura  and
Hiroshi Honda
Yamato Shimomiya
Affiliation:
Department of Clinical Application, Ziosoft Inc.Tokyo, Japan
Michinobu Nagao*
Affiliation:
Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women’s Medical University, Tokyo, Japan
Yuzo Yamasaki
Affiliation:
Department of Clinical Radiology, Kyushu University, Fukuoka, Japan
Takashi Shirasaka
Affiliation:
Medical Technology, Kyushu University, Fukuoka, Japan
Masatoshi Kondo
Affiliation:
Medical Technology, Kyushu University, Fukuoka, Japan
Tsukasa Kojima
Affiliation:
Medical Technology, Kyushu University, Fukuoka, Japan
Akihiro Nishie
Affiliation:
Department of Clinical Radiology, Kyushu University, Fukuoka, Japan
Kenichiro Yamamura
Affiliation:
Pediatrics, Kyushu University, Fukuoka, Japan
Hiroshi Honda
Affiliation:
Department of Clinical Radiology, Kyushu University, Fukuoka, Japan
*
Correspondence to: Michinobu Nagao, Department of Diagnostic Imaging & Nuclear Medicine, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan. Tel: +81-3-3353-8111; Fax: +81-3-5269-9247; E-mail: nagao.michinobu@twmu.ac.jp.
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Abstract

Introduction

We propose a new dynamic flow imaging using 320-detector row CT, and investigate the assessment of coronary flow in aneurysms of Kawasaki disease in adulthood.

Methods

Six patients with Kawasaki disease and coronary aneurysms associated (26.7 years old) and six controls were enrolled. Dynamic coronary CT angiography with 320-row CT was continuously performed at mid-diastole throughout 15–25 cardiac cycles with prospective Electrocardiogram gating after injection of contrast media. Dynamic data sets of 15–25 cycles were computed into 90–100 data sets by motion coherence image processing. Next, time–density curves for coronary arteries were calculated for all the phases. On the basis of the maximum slope method, coronary flow index was defined as the ratio of the maximum upslope of the attenuation of coronary arteries to the upslope of the attenuation of ascending aorta on the time–density curves. Coronary flow indexes for the proximal and distal sites of coronary arteries and intra-aneurysm were measured.

Keywords

CTmotion coherence image processingKawasaki diseasecoronary artery aneurysmgeneral cardiology
Type
Original Articles
Information
Cardiology in the Young , Volume 28 , Issue 3 , March 2018 , pp. 416 - 420
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Copyright
© Cambridge University Press 2017 

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References

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