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Cholesterol-lowering potential in human subjects of fat from pigs fed rapeseed oil

Published online by Cambridge University Press:  09 March 2007

Brittmarie Sandström ,
Susanne Bügel ,
Charlotte Lauridsen ,
Flemming Nielsen ,
Claus Jensen  and
Leif H. Skibsted
Brittmarie Sandström*
Affiliation:
Research Department of Human Nutrition, The Royal Veterinary and Agricultural University, DK-1958, Frederiksberg C, Denmark
Susanne Bügel
Affiliation:
Research Department of Human Nutrition, The Royal Veterinary and Agricultural University, DK-1958, Frederiksberg C, Denmark
Charlotte Lauridsen
Affiliation:
Department of Animal Nutrition and Physiology Danish Institute of Agricultural Science, DK-8830, Tjele, Denmark
Flemming Nielsen
Affiliation:
Department of Environmental Medicine Odense University, DK-5000, Odense C, Denmark
Claus Jensen
Affiliation:
Department of Dairy and Food Science, The Royal Veterinary and Agricultural University, DK-1958, Frederiksberg C, Denmark
Leif H. Skibsted
Affiliation:
Department of Dairy and Food Science, The Royal Veterinary and Agricultural University, DK-1958, Frederiksberg C, Denmark
*
*Corresponding author: Dr Brittmarie Sandström, fax +45 3528 2483, email bsa@kvl.dk
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Abstract

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The possibility of achieving blood-lipid-lowering characteristics of pig fat by increasing the content of unsaturated fat in pig feed was evaluated. Three pig feeding regimens were applied: basal feed (no added fat or vitamin E), basal feed + rapeseed oil (60 g/kg feed), and basal feed + rapeseed oil (60 g/kg) + vitamin E (200 mg/kg). Meat and meat products from the three pig groups were incorporated into diets providing 86 g pig fat/10 MJ. The diets were served to twelve healthy human male subjects for 3 weeks each in a randomised crossover design. The diets prepared from pigs fed rapeseed oil had a lower content of saturated fatty acids (approximately 9 v. 11 % of energy) and a higher content of polyunsaturated fatty acids (approximately 6 v. 4 % of energy) than the diet prepared from pigs fed the basal feed. Diets based on fat from pigs fed the rapeseed oil resulted in significantly lower (approximately 4 %, P = 0·019) total serum cholesterol concentration compared with the diet from pigs fed the basal feed. No differences were observed in LDL-, HDL- or VLDL-cholesterol, or in triacylglycerol or VLDL-triacylglycerol concentrations. Addition of vitamin E to the pig feed resulted in only a minor increase in vitamin E content in the human subjects' diet and the vitamin E content was low in all three pig diets. Plasma vitamin E concentration in the human subjects at the end of the period with diets from pigs fed rapeseed oil without vitamin E was significantly lower (P = 0·04) than in the other two diet periods. In conclusion, an increased content of rapeseed oil in pig feed changes the fatty acid composition of the pig fat in a way that has a potential to reduce blood cholesterol concentrations in human subjects. However, intake of pig fat with a higher content of unsaturated fatty acids needs to be matched by a higher dietary intake of vitamin E.

Keywords

Rapeseed oilDietary fatty acidsBlood lipidsPig feed composition
Type
Research Article
Information
British Journal of Nutrition , Volume 84 , Issue 2 , August 2000 , pp. 143 - 150
Copyright
Copyright © The Nutrition Society 2000

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