Hostname: page-component-8448b6f56d-gtxcr Total loading time: 0 Render date: 2024-04-24T04:27:21.605Z Has data issue: false hasContentIssue false
  • English
  • Français

The effect of immunoneutralization of PMSG at a gonadotropin-induced oestrus on the duration of ovulation and reproductive performance of sows

Published online by Cambridge University Press:  02 September 2010

R. N. Kirkwood ,
N. M. Soede ,
G. W. Dyck  and
P. A. Thacker
R. N. Kirkwood
Affiliation:
Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W0
N. M. Soede
Affiliation:
Department of Animal Husbandry, Agricultural University, Wageningen, The Netherlands
G. W. Dyck
Affiliation:
Agriculture and Agri-food Canada Research Centre, Brandon, Manitoba, Canada R7A 5Y3
P. A. Thacker
Affiliation:
Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0W0
Get access

Abstract

Two experiments were performed to examine the effects of immunoneutralizing PMSG at the onset of oestrus on the reproductive performance of sows. In experiment 1, 12 multiparous sows received 750 i.u. PMSG at weaning and six sozus acted as controls and were injected with saline. At 84 h after PMSG injection, all sows received an injection of 500 i.u. human chorionic gonadotropin (hCG) and six of the PMSG-treated sows also received an injection of 750 i.u. of a monoclonal anti-PMSG serum. The ovaries of all sows were examined by real time ultrasonography at 60-min intervals from 36 to 48 h after hCG injection for evidence of ovulation. In sows observed to ovulate, there was no significant effect of treatment on the interval from hCG injection to the start of ovulation, the duration of ovulation or subsequent litter size. In experiment 2, 253 primiparous sows received injections at weaning of 750 i.u. PMSG (no. = 134), 400 i.u. PMSG plus 200 i.u. hCG (no. = 69) or served as controls (no. = 50). At breeding, 67 of the PMSG-treated sows received an injection of 750 i.u. of monoclonal anti-PMSG serum.

More gonadotropin-treated than control sows were bred by 7 days after weaning (P < 0·05). Farrowing rates were higher in sows receiving the PMSG followed by anti-PMSG and PMSG plus hCG than in controls (P < 0·05), with those receiving PMSG alone being intermediate. There was no effect of treatment on subsequent litter sizes. These data indicate that the reproductive performance of primiparous sows may be improved by gonadotropin administration at the time of weaning. However, there was no advantage to using any particular hormone combination or anti-PMSG.

Keywords

immunoneutralizationovulationPMSGreproductive performancesows
Type
Research Article
Information
Animal Science , Volume 61 , Issue 2 , October 1995 , pp. 321 - 324
Copyright
Copyright © British Society of Animal Science 1995

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aherne, F. X. and Kirkwood, R. N. 1985. Nutrition and sow prolificacy. Journal of Re-production and Fertility 33: suppl., pp. 169–183.Google ScholarPubMed
Almond, G. W. 1992. Factors affecting the reproductive performance of the weaned sow. Veterinary Clinics of North America: Food Animal Practice 8: 503–515.Google ScholarPubMed
Brüssow, K.-P. 1992. The influence of PMSG antisera on the level of steroid hormones and the embryonic quality in superovulated gilts. Archiv Fuer Tierzucht Dummerstorf 351: 603–609.Google Scholar
Dieleman, S. J. and Bevers, M. M. 1987. Effects of monoclonal antibody against PMSG administered shortly after the preovulatory LH surge on time and numbers of ovulations in PMSG/PG-treated cows, journal of Reproduction and Fertility 81: 533–542.CrossRefGoogle ScholarPubMed
Hurtgen, J. P. and Leman, A. D. 1979. Use of PMSG in the prevention of seasonal post weaning anestrus in sows. Theriogenology 12: 207–214.CrossRefGoogle ScholarPubMed
King, R. H., Killeen, I. D. and Vercoe, J. 1990. Efficacy of exogenous gonadotrophic hormones to induce estrus in anestrus gilts. Theriogenology 34: 761–766.CrossRefGoogle Scholar
Kirkwood, R. N., Peacock, A. J., Van Lunen, T. A. and Thacker, P. A. 1994. The effect of immunoneutralization of PMSG near a gonadotropin-induced oestrus on the reproductive performance of gilts. Animal Production 58: 401–404.Google Scholar
Kirkwood, R. N. and Thacker, P. A. 1992. Influence of PMSG antiserum on serum progesterone and estrous cycles of PMSG-treated gilts. Canadian journal of Animal Science 72: 173–176.CrossRefGoogle Scholar
Kirkwood, R. N., Thacker, P. A. and Chaplin, R. K. 1991. The influence of exogenous gonadotrophins and cloprostenol on ovulation in gilts. Canadian Veterinary Journal 32: 742–746.Google ScholarPubMed
Leman, A. D. 1992. Optimizing farrowing rate and litter size and minimizing nonproductive sow days. Veterinary Clinics of North America: Food Animal Practice 8: 609–621.Google ScholarPubMed
Martemucci, G., D'AIessandro, A., Toteda, F., Gambacorta, M. and Bellitti, E. 1993. Effect of injection time of monoclonal anti-PMSG on ovarian response and embryo production in superovulated ewes. Proceedings of the seventh world conference on animal production vol. 2, 274–275.Google Scholar
Paterson, A. M. 1982. The controlled induction of puberty. In Control of pig reproduction (ed. Cole, D. J. A. and Foxcroft, G. R.), pp. 139–159. Butterworths, London.CrossRefGoogle Scholar
Soma, J. A. and Speer, V. C. 1975. Effect of pregnant mare serum and chlortetracycline on the reproductive efficiency of sows. Journal of Animal Science 41: 100–105.CrossRefGoogle ScholarPubMed