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Validating the Chinese version of the Verbal Learning Test for screening Alzheimer’s disease

Published online by Cambridge University Press:  11 December 2009

CHIUNG CHIH CHANG ,
JOEL H. KRAMER ,
KER NENG LIN ,
WEN NENG CHANG ,
YA-LING WANG ,
CHI-WEI HUANG ,
YU TING LIN ,
CHING CHEN  and
PEI NING WANG
CHIUNG CHIH CHANG
Affiliation:
Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung, Taiwan
JOEL H. KRAMER
Affiliation:
Memory and Aging Center, University of California, San Francisco, California
KER NENG LIN
Affiliation:
Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan Department of Psychology, Fu Jen Catholic University, Taipei County, Taiwan, Taipei, 112, Taiwan
WEN NENG CHANG
Affiliation:
Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung, Taiwan
YA-LING WANG
Affiliation:
Department of Psychiatry, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung, Taiwan
CHI-WEI HUANG
Affiliation:
Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung, Taiwan
YU TING LIN
Affiliation:
Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung, Taiwan
CHING CHEN
Affiliation:
Department of Psychiatry, Chang Gung Memorial Hospital-Kaohsiung Medical Center and Chang Gung University College of Medicine, Kaohsiung, Taiwan
PEI NING WANG*
Affiliation:
Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan Department of Neurology, School of Medicine, National Yang-Ming University, Taipei, 112, Taiwan
*
*Correspondence and reprint requests to: Pei Ning Wang, Department of Neurology, Taipei Veterans General Hospital, Taipei, 112, Taiwan. E-mail: pnwang@vghtpe.gov.tw
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Abstract

Episodic memory tasks are one of the most sensitive tools to discriminate Alzheimer’s disease (AD). This study aimed to validate a shorter version verbal memory test that will efficiently assess Chinese elderly with memory complaints. One hundred and eighty-five elderly with normal cognition (NC) and 217 AD patients were evaluated. Each participant received the Chinese Version Verbal Learning Test (CVVLT) consisting of 9 two-character nouns with 4 learning trials, 2 delayed recalls in 30 seconds and 10 minutes, and a word recognition test. In the NC elderly, age and sex had significant effects on recall scores in CVVLT, while education level showed an inverse correlation with 3 different patterns of errors made during the learning, recall, and recognition trials. AD patients had lower scores across all recall tests. In those with lower educational level, NC elderly had higher perseveration errors than AD patients. The cutoff value between the AD and NC groups in the 10-minute recall was 4/5 for those aged >75 years and 5/6 for those aged <75 years. This study has good validity in discriminating AD participants and the data here can help in diagnosing AD and mild cognitive impairment using the CVVLT. (JINS, 2010, 16, 244–251.)

Keywords

Chinese Verbal Learning Testeducationmemorydementiacutoff valuevalidation
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 16 , Issue 2 , March 2010 , pp. 244 - 251
Copyright
Copyright © The International Neuropsychological Society 2009

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References

REFERENCES

American Psychiatric Association. (1994). Diagnostic and Statistical Manual of Mental Disorders, (DSM-IV) (4th ed.). Washington, DC: American Psychiatric Association.Google Scholar
Au, A., Chan, A.S., & Chiu, H. (2003). Verbal learning in Alzheimer’s dementia. Journal of the International Neuropsychological Society, 9, 363–375.CrossRefGoogle ScholarPubMed
Defer, G.L., Daniel, F., & Marie, R.M. (2006). Study of episodic memory in multiple sclerosis using the California Verbal Learning Test: The data favour altered encoding. Revue Neurologique, 162, 852–857.CrossRefGoogle ScholarPubMed
Delis, D.C., Freeland, J., Kramer, J.H., & Kaplan, E. (1988). Integrating clinical assessment with cognitive neuroscience: Construct validation of the California Verbal Learning Test. Journal of Consulting Clinical Psychology, 56, 123–130.CrossRefGoogle ScholarPubMed
Delis, D.C., Kramer, J.H., Kaplan, E., & Ober, B.A. (1987). The California Verbal Learning Test: Research edition, Adult version. San Antonio, TX: The Psychological Corporation.Google Scholar
Dorrego, M.F., Sabe, L., Garcia Cuerva, A., Kuzis, G., Tiberti, C., Boller, F., & Starkstein, S.E. (1999). Remote memory in Alzheimer’s disease. Journal of Neuropsychiatry and Clinical Neuroscience, 11, 490–497.CrossRefGoogle ScholarPubMed
Dubois, B., Feldman, H.H., Jacova, C., Dekosky, S.T., Barberger-Gateau, P., Cummings, J., et al. (2007). Research criteria for the diagnosis of Alzheimer’s disease: Revising the NINCDS-ADRDA criteria. Lancet Neurology, 6, 734–746.CrossRefGoogle ScholarPubMed
Elwood, R.W. (1995). The California Verbal Learning Test: Psychometric characteristics and clinical application. Neuropsychology Review, 5, 173–201.CrossRefGoogle ScholarPubMed
Folstein, M.F., Folstein, S.E., & McHugh, P.R. (1975). “Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189–198.CrossRefGoogle ScholarPubMed
Fuld, P.A., Katzman, R., Davies, P., & Terry, R.D. (1982). Intrusions as a sign of Alzheimer dementia: Chemical and pathological verification. Annals of Neurology, 11, 155–159.CrossRefGoogle ScholarPubMed
Hughes, C.P., Berg, L., Danziger, W.L., Coben, L.A., & Martin, R.L. (1982). A new clinical scale for the staging of dementia. British Journal of Psychiatry, 140, 566–572.CrossRefGoogle ScholarPubMed
Huh, T.J., Kramer, J.H., Gazzaley, A., & Delis, D.C. (2006). Response bias and aging on a recognition memory task. Journal of the International Neuropsychological Society, 12, 1–7.CrossRefGoogle ScholarPubMed
Lee, T., Yuen, K., & Chan, C. (2002). Normative data for neuropsychological measures of fluency, attention, and memory measures for Hong Kong Chinese. Journal of Clinical and Experimental Neuropsychology, 24, 615–632.CrossRefGoogle ScholarPubMed
Lekeu, F., Magis, D., Marique, P., Delbeuck, X., Bechet, S., Guillaume, B., et al. (2009). The California Verbal Learning Test and other standard clinical neuropsychological tests to predict conversion from mild memory impairment to dementia. Journal of Clinical and Experimental Neuropsychology, 20, 1–12.Google Scholar
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E.M. (1984). Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology, 34, 939–944.CrossRefGoogle ScholarPubMed
Mohs, R.C. (1996). The Alzheimer’s Disease Assessment Scale. International Psychogeriatrics, 8, 195–203.CrossRefGoogle ScholarPubMed
Otto, M.W., Bruder, G.E., Fava, M., Delis, D.C., Quitkin, F.M., & Rosenbaum, J.F. (1994). Norms for depressed patients for the California Verbal Learning Test: Associations with depression severity and self-report of cognitive difficulties. Archives of Clinical Neuropsychology, 9, 81–88.CrossRefGoogle ScholarPubMed
Petersen, R.C., Jack, C.R. Jr., Xu, Y.C., Waring, S.C., O’Brien, P.C., Smith, G.E., et al. (2000). Memory and MRI-based hippocampal volumes in aging and AD. Neurology, 54, 581–587.CrossRefGoogle ScholarPubMed
Ponton, M.O., Satz, P., Herrera, L., Ortiz, F., Urrutia, C.P., Young, R., et al. (1996). Normative data stratified by age and education for the Neuropsychological Screening Battery for Hispanics (NeSBHIS): Initial report. Journal of the International Neuropsychological Society, 2, 96–104.CrossRefGoogle ScholarPubMed
Reite, M., Cullum, C.M., Stocker, J., Teale, P., & Kozora, E. (1993). Neuropsychological test performance and MEG-based brain lateralization: Sex differences. Brain Research Bulletin, 32, 325–328.CrossRefGoogle ScholarPubMed
Soininen, H.S., & Scheltens, P. (1998). Early diagnostic indices for the prevention of Alzheimer’s disease. Annals of Medicine, 30, 553–559.CrossRefGoogle ScholarPubMed
Taylor, A.E., Saint-Cyr, J.A., & Lang, A.E. (1990). Memory and learning in early Parkinson’s disease: Evidence for a “frontal lobe syndrome”. Brain Cognition, 13, 211–232.CrossRefGoogle ScholarPubMed
Welsh, K.A., Butters, N., Hughes, J.P., Mohs, R.C., & Heyman, A. (1992). Detection and staging of dementia in Alzheimer’s disease. Use of the neuropsychological measures developed for the Consortium to Establish a Registry for Alzheimer’s Disease. Archives of Neurology, 49, 448–452.CrossRefGoogle ScholarPubMed
Woodard, J.L., Goldstein, F.C., Roberts, V.J., & McGuire, C. (1999). Convergent and discriminant validity of the CVLT (dementia version). California Verbal Learning Test. Journal of Clinical and Experimental Neuropsychology, 21, 553–558.CrossRefGoogle ScholarPubMed