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Low-temperature Plasma Processing of Micro- and Nanostructured Materials for Biomedical Applications

Published online by Cambridge University Press:  16 May 2012

Masaaki Nagatsu ,
Roman V. Bekarevich ,
Alexei Balmakov ,
Iuliana Motrescu ,
Akihisa Ogino ,
Akiko Murakawa  and
Enoch Y. Park
Masaaki Nagatsu
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Roman V. Bekarevich
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Alexei Balmakov
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Iuliana Motrescu
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Akihisa Ogino
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Akiko Murakawa
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
Enoch Y. Park
Affiliation:
Graduate School of Science and Technology, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan
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Abstract

We develop a plasma processing technique for modifying the surface properties of micro- and nanostructured materials for biomedical applications. We also investigate the physical and chemical roles of the plasma in modifying the surfaces of micro- and nanostructured materials such as magnetic nanoparticles (MNPs), carbon nanotubes (CNTs), nanophosphors, and biomolecules for various biomedical applications. We introduced amino groups onto the surfaces of graphite-encapsulated iron compound nanoparticles using a low-pressure Ar plasma pre-treatment and ammonia plasma post-treatment followed by immobilization of biomolecules, such as dextran and N-acetyllactosamine (LacNAc). The present technique was also used to introduce amino groups onto CNT dot arrays grown on Si substrates for use in biochip sensors.

Keywords

biomedicalnanostructuresurface chemistry
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1469: Symposium WW – Plasma Processing and Diagnostics for Life Sciences , 2012 , mrss12-1469-ww08-02
Copyright
Copyright © Materials Research Society 2012

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References

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