Published online by Cambridge University Press: 23 June 2020
Regional anesthesia has undergone a great deal of growth in recent years, due in part to the ability of peripheral nerve blockade to treat pain without the administration of opioids, and the resultant avoidance of their systemic side effects, such as respiratory depression, sedation, nausea, and constipation. In addition to this advantage, adequate control of acute pain as can be achieved with regional techniques prevents the central sensitization that can result in chronic (including phantom limb) pain. Reduced exposure to opioids also decreases the risk of physical dependence and addiction. Regional techniques have also been demonstrated to reduce hospital length of stay.
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