The Pan American Health Organization (PAHO, World Health Organization [WHO] for the Americas) began to promote health technology assessment (HTA) in the Americas as early as 1983 (under the leadership of Dr. David Banta, Mr. Jorge Peña, and Dr. Gloria Coe) (Reference Banta2). There was a Technology Development Unit from the mid-1980s until the early 1990s that supported some important national and international meetings and consultations (3;4;Reference Panerai and Pena Mohr8;Reference Peña Mohr and Coe9). In 1998, PAHO published a Regional Strategy for HTA (7). Some studies (assessment) were conducted and published and documents from the Office of Technology Assessment were translated into Spanish and widely disseminated in the region. However, these early activities did not result in any great change in Latin America and the Caribbean policies.

In the mid- to late-1990s, health sector reform became an important movement in Latin America, and PAHO became more active in promoting HTA (under the direct leadership of Dr. Alberto Infante) (5;6). Collaboration of the HTA Agencies from Spain and Canada led to several workshops on HTA and training a critical mass of professionals linked to the decision-making process in Latin America and the Caribbean (225 professionals). Workshops were held in Canada, Mexico, Colombia, Cuba, Panama, Argentina, Chile, and Peru. Several countries, notably Mexico, Brazil, Argentina, Uruguay, and Chile, showed increasing interest in HTA. In 1997, MERCOSUR (Argentina, Brazil, Paraguay, and Uruguay economic initiative) organized a Technical Subcommittee on HTA.

In 1998 in the II Summit of the Americas (Head of States and Governments of the Countries of the Americas), Santiago de Chile, April 18–19, the work plan included a chapter on “Health Technology Bridging the Americas.” In the year 2000, HTA was included as one of the Essential Public Health Functions in PAHO documents and thinking. PAHO became a member of ISTAHC and promoted the participation of experts from Latin America and the Caribbean in the Annual Meetings. Some academic centers began to carry out HTA studies. PAHO produced some bilingual (English/Spanish) publications on HTA (5;6).

Since 2000, PAHO (under the leadership of Mr. Antonio Hernandez) has redefined the approach to heath technology in the interaction with the countries of the region and has prioritized the strengthening of HTA programs as part of the new approach. PAHO is promoting and supporting the participation of experts in international conferences and training programs (Ulysses and the distant learning course on Health Technology Assessment, AETMIS); collaborating in the organization of HTA Agencies and Centers in the countries; facilitating access to HTA information and databases; and sponsoring internships in HTA. To facilitate the interaction and communication exchange among the experts, a virtual network based on the Internet (Listserv Group hta@listserv.paho.org) was organized in 2004.

About 2006, as described by Frenk et al. in this volume, Mexico developed a national office of HTA, the National Centre for Excellence in Health Technology (CENETEC) http://www.cenetec.salud.gob.mx/, that has considerable resources and ambitious programs related to health technology assessment and management. Since 2004, an annual international seminar involving mainly Latin American countries has been held in Mexico City under the leadership of the Mexican CENETEC and cosponsored by PAHO.

In Brazil, as described by Banta and Almeida in this issue, a policy toward health technology management was published in 2006, which began to lead to institutionalization of HTA in the national government.

Argentina's approach to HTA, including the use of HTA in insurance coverage decision, is described by Rubenstein et al. in this volume. The Instituto de Efectividad Clínica Sanitaria (IECS) of Argentina http://www.iecs.org.ar/ has developed a training program in HTA.

Cuba has focused on HTA and evidence-based medicine in its health programs in recent years.

Chile developed an office for HTA in its Ministry of Health in 1997 (ETESA—the Unit for Health Technology Assessment, a member of INAHTA). The ETESA is part of the Department of Quality and Patient Safety of the Ministry. Its goal is to generate assessment reports, technical notes, and recommendations based on evidence according to the priorities set by the Ministry of Health.

In Colombia, the Ministry of Social Protection with the PAHO collaboration is organizing a HTA Agency with the active participation of the academic sector.

In Uruguay, the Ministry of Health has an HTA program in the Department of Medical Technology and is active in the MERCOSUR initiative.

In 2001, the Ministry of Health of Trinidad and Tobago initiated a Health Sector Reform movement and gave emphasis to the development of a quality strategy, including the organization of a HTA program. In 2007, the Ministry of Health began to develop an HTA policy framework.

In March 2007, the World Heath Organization, in the 60th World Health Assembly, passed Resolution WHA60.29 on Health Technologies. The resolution urges the Member States to work on health technologies (10).

In 2007, INAHTA, IECS, and CENETEC, with the collaboration of PAHO, conducted a survey to assess the status of HTA in Latin America and the Caribbean and the options for an International Collaboration with INAHTA. The results were presented in HTAi 2008 Meeting in Montreal. Some of the information in this study was taken from that survey.

In HTAi 2008, there was a significant increase in participation from Latin American Countries (Argentina, Brazil, Colombia, Costa Rica, Mexico, Panama, Peru, and Uruguay). The preconference workshop “HTA in Latin America: has the time come for an HTA network?” gave a basis for the organization of a HTA Network in Latin America.

The trend in Latin America seems to be toward increasing activity and interest in HTA (Reference Banta1;6). During the next few years, efforts to institutionalize HTA as part of public health policy will probably be seen in other countries.