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Fulminant cytomegalovirus myocarditis in an infant with concomitant large atrial and ventricular septal defects: medical intervention strategy for functional cardiac regeneration

Published online by Cambridge University Press:  21 December 2018

Roland Schrewe Open the ORCID record for Roland Schrewe [Opens in a new window] ,
Anoosh Esmaeili ,
Kachina Behnke-Hall  and
Dietmar Schranz
Roland Schrewe*
Affiliation:
Pediatric Cardiology, Goethe University, Frankfurt/Main, Germany
Anoosh Esmaeili
Affiliation:
Pediatric Cardiology, Goethe University, Frankfurt/Main, Germany
Kachina Behnke-Hall
Affiliation:
Pediatric Cardiology, Goethe University, Frankfurt/Main, Germany
Dietmar Schranz
Affiliation:
Pediatric Cardiology, Goethe University, Frankfurt/Main, Germany
*
Author for correspondence: Dr. R. Schrewe (Medicine), Universitätsklinikum Frankfurt, Zentrum der Kinderheilkunde und Jugendmedizin, Pädiatrische Kardiologie und Angeborene Herzfehler, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Tel: +49-069-63016022; Fax: +49-069-63016437; E-mail: Roland.schrewe@kgu.de
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Abstract

A cytomegalovirus-associated heart failure in a young infant with atrial and ventricular septal defects is reported in this case report. The patient recovered by an anti-congestive and anti-viral therapy with an extra percutaneous transcatheter treatment strategy. In the context of bi-ventricular predominant right heart failure associated with supra-systemic pulmonary hypertension, the already closed arterial duct was re-opened and stented to unload the right ventricle and thereby augment the systemic blood flow. Either the left-to-right shunting atrial septal defect or bi-directional shunting ventricular septal defect was involved in the disease process and was not able to avoid global heart failure. After clinical improvement, the stented duct was shunted left-to-right and was occluded with an ADO-II-AS. During the same procedure the atrial septal defect was closed with an Amplatzer-ASD occluder, while the peri-membranous ventricular septal defect was closed with an ADO-II occluder 2 months later.

Keywords

Cytomegalovirusheart failurepulmonary hypertensionre-ductingtranscatheter cardiac shunt closure
Type
Original Article
Information
Cardiology in the Young , Volume 29 , Issue 3 , March 2019 , pp. 277 - 279
Copyright
© Cambridge University Press 2018. 

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Footnotes

Cite this article: Schrewe R, Esmaeili A, Behnke-Hall K, Schranz D. (2019) Fulminant cytomegalovirus myocarditis in an infant with concomitant large atrial and ventricular septal defects: medical intervention strategy for functional cardiac regeneration. Cardiology in the Young29: 277–279. doi: 10.1017/S1047951118002160

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