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Intake and sources of phylloquinone (vitamin K1) in 4-year-old British children: comparison between 1950 and the 1990s

Published online by Cambridge University Press:  02 January 2007

CJ Prynne ,
CW Thane ,
A Prentice  and
MEJ Wadsworth
CJ Prynne*
Affiliation:
MRC Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
CW Thane
Affiliation:
MRC Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
A Prentice
Affiliation:
MRC Human Nutrition Research, Elsie Widdowson Laboratory, Fulbourn Road, Cambridge CB1 9NL, UK
MEJ Wadsworth
Affiliation:
MRC National Survey of Health and Development, University College and Royal Free Medical School, 1–19 Torrington Place, London, WC1E 6BT, UK
*
*Corresponding author: Email celia.greenberg@mrc-hnr.cam.ac.uk
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Abstract

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Objective

To compare dietary intake and sources of phylloquinone (vitamin K1) in 4-year-old British children between 1950 and the 1990s, and report their variation by sociodemographic factors.

Design

Nationally representative samples of 4-year-olds from the longitudinal Medical Research Council National Survey of Health and Development (NSHD) (1950) and the cross-sectional National Diet and Nutrition Surveys (NDNS, 1992/93 and 1997).

Setting

Great Britain.

Subjects

Subjects were 4599 children born on 3–9 March 1946 (NSHD) and 307 children in the 1990s (NDNS).

Results

Geometric mean dietary phylloquinone intake was significantly higher in 1950 (39 μg day−1, 95% confidence interval (CI) 37, 40) compared with the 1990s (24 μg day−1, 95% CI 22, 25) (P < 0.001). This difference remained when intake was expressed per MJ energy intake and per kilogram body weight, and after accounting for sex, region and occupational social class of the family. In 1950, phylloquinone intake in Scotland was significantly lower than in the rest of Britain. By the 1990s these regional differences had disappeared. Food sources of phylloquinone intake changed significantly between 1950 and the 1990s, with fats and oils contributing more and vegetables less, although vegetables contributed most (60% and 48%, respectively) to phylloquinone intake in both surveys.

Conclusions

Phylloquinone intakes of children have decreased significantly since 1950. With the suggested need for adequate phylloquinone intake for optimal development and maintenance of bone and the cardiovascular system, the substantially lower phylloquinone intakes reported in children of the 1990s, compared with 1950, may have implications for the health of these two systems in later adulthood.

Keywords

PhylloquinoneVitamin KIntakeFood sourcesChildrenGreat Britain
Type
Research Article
Information
Public Health Nutrition , Volume 8 , Issue 2 , April 2005 , pp. 171 - 180
Copyright
Copyright © The Authors 2005

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