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When unexploded ordnance (UXO) is embedded in the body, the effect of explosive weapons used in conflict is amplified. Though relatively rare, such events present potentially devastating consequences for the patient and medical providers as routine diagnostic and therapeutic procedures hold potential to initiate detonation of the embedded UXO (eUXO). The objective is to identify and synthesize available literature relating to the management of eUXO in low resource settings.
Methods
A scoping review was conducted using PRISMA-ScR methodology to evaluate literature in all languages from all date ranges until January 31, 2024, discussing the management of casualties with eUXO, including types of ordnance, injury patterns, diagnostics, resource utilization, surgical interventions, and outcomes.
Results
Search strings identified 3,425 records. After title and abstract screening 3,397 were excluded yielding 18 for full text screening of which 5 were excluded. Therefore 13 reports were included in analysis. Data variable reporting was heterogeneous but themes and subthemes regarding safety, planning and communication emerged.
Conclusions
A scoping review was conducted to identify gaps in existing literature on the management of eUXO in low resource settings. Coordinated engagement from personnel representing a variety of clinical and non-clinical specialties is required to safely manage eUXO.
Simulation materials for layperson first responder (LFR) trainings used in high-resource settings are prohibitively expensive for use in low- and low-middle income countries. To date, no structured approach to community-engaged design in identifying accessible and acceptable simulation materials for LFR trainings has been developed.
Methods
We conducted 2 workshops with male (18) and female participants (10) in a rural village in the Centre-Est region of Burkina Faso using principles of community-engaged research to define solutions for improvised LFR training materials.
Results
Participants reported a range of reactions to the use of live trainees and animal models for LFR training including considerations around gender sensitivity, use of animals for training purposes in regions of food insecurity, and religious and cultural barriers to consumption of meat after use for training purposes. A range of locally available options for training materials was identified by participants.
Conclusions
Significant sociocultural variability exists across low-resource environments with implications for the acceptability and availability of improvised materials for LFR training. Affected communities should be engaged in the selection and design of improvisation strategies to ensure context-appropriate adaptation.
Humanitarian mine action (HMA) stakeholders have an organized presence with well-resourced medical capability in many conflict and post-conflict settings. Humanitarian mine action has the potential to positively augment local trauma care capacity for civilian casualties of explosive ordnance (EO) and explosive weapons (EWs). Yet at present, few strategies exist for coordinated engagement between HMA and the health sector to support emergency care system strengthening to improve outcomes among EO/EW casualties.
Methods:
A scoping literature review was conducted to identify records that described trauma care interventions pertinent to civilian casualties of EO/EW in resource-constrained settings using structured searches of indexed databases and grey literature. A 2017 World Health Organization (WHO) review on trauma systems components in low- and middle-income countries (LMICs) was updated with additional eligible reports describing trauma care interventions in LMICs or among civilian casualties of EO/EWs after 2001.
Results:
A total of 14,195 non-duplicative records were retrieved, of which 48 reports met eligibility criteria. Seventy-four reports from the 2017 WHO review and 16 reports identified from reference lists yielded 138 reports describing interventions in 47 countries. Intervention efficacy was assessed using heterogenous measures ranging from trainee satisfaction to patient outcomes; only 39 reported mortality differences. Interventions that could feasibly be supported by HMA stakeholders were synthesized into a bundle of opportunities for HMA engagement designated links in a Civilian Casualty Care Chain (C-CCC).
Conclusions:
This review identified trauma care interventions with the potential to reduce mortality and disability among civilian EO/EW casualties that could be feasibly supported by HMA stakeholders. In partnership with local and multi-lateral health authorities, HMA can leverage their medical capabilities and expertise to strengthen emergency care capacity to improve trauma outcomes in settings affected by EO/EWs.
The launch of NASA’s next exoplanet mission, the Transiting Exoplanet Survey Satellite (TESS), took place successfully on 2018 April 18, and has now commenced science operations. TESS is specifically designed to search for exoplanets transiting the closest and brightest stars using high-cadence photometric measurements. The images employed for detecting those planets can also be used for a wide variety of time-domain astronomy, especially when considering the full-frame images that TESS takes every 30 minutes. This (pre-launch) workshop familiarised participants with the details of how TESS will operate, described the expected data products and how to access them, introduced the software suite PyKE, which can be used to analyse TESS data, and highlighted ways for participants to request additional TESS targets.
The Transiting Exoplanet Survey Satellite (TESS) is a NASA Astrophysics Explorer-class mission that will perform an all-sky survey to search for planets transiting nearby bright stars. The primary goal is to search for planets smaller than Neptune that are amenable to follow-up spectroscopic observations that will yield planet masses, thereby providing prime targets for future atmospheric characterization studies. In its two-year prime mission, TESS will monitor more than 200,000 stars with four wide-field optical CCD cameras that will tile more than 90% of the sky. TESS will also obtain full-frame images (FFIs) of the entire field of view with a cadence of 30 minutes to facilitate additional science. These FFIs will provide photometry for more than 30 million objects brighter than magnitude I =16 during the two-year prime mission. The TESS legacy will be a catalogue of the nearest and brightest main-sequence stars hosting transiting exoplanets. The TESS Mission will also have a robust Guest Investigator (GI) Programme that will be managed by the TESS Science Support Center at NASA Goddard Space Flight Center. Under the GI programme, the astrophysics community may propose new 2-minute cadence targets and investigations using the 30-minute cadence FFI data. TESS GI calls for proposals will occur once per year, and about 20,000 targets will be available for each GI programme cycle.
TESS was launched in April 2018, and will observe from a unique elliptical high-Earth orbit that will provide an unobstructed view of its field to obtain continuous light-curves.
This study aimed to document the growth and challenges encountered in the decade since inception of the National Ambulance Service (NAS) in Ghana, West Africa. By doing so, potentially instructive examples for other low- and middle-income countries (LMICs) planning a formal prehospital care system or attempting to identify ways to improve existing emergency services could be identified.
Methods
Data routinely collected by the Ghana NAS from 2004-2014 were described, including: patient demographics, reason for the call, response location, target destination, and ti1mes of service. Additionally, the organizational structure and challenges encountered during the development and maturation of the NAS were reported.
Results
In 2004, the NAS piloted operations with 69 newly trained emergency medical technicians (EMTs), nine ambulances, and seven stations. The NAS expanded service delivery with 199 ambulances at 128 stations operated by 1,651 EMTs and 47 administrative and maintenance staff in 2014. In 2004, nine percent of the country was covered by NAS services; in 2014, 81% of Ghana was covered. Health care transfers and roadside responses comprised the majority of services (43%-80% and 10%-57% by year, respectively). Increased mean response time, stable case holding time, and shorter vehicle engaged time reflect greater response ranges due to increased service uptake and improved efficiency of ambulance usage. Specific internal and external challenges with regard to NAS operations also were described.
Conclusion
The steady growth of the NAS is evidence of the need for Emergency Medical Services and the effects of sound planning and timely responses to changes in program indicators. The way forward includes further capacity building to increase the number of scene responses, strengthening ties with local health facilities to ensure timely emergency medical care and appropriateness of transfers, assuring a more stable funding stream, and improving public awareness of NAS services.
ZakariahA, StewartBT, BoatengE, AchenaC, TansleyG, MockC. The Birth and Growth of the National Ambulance Service in Ghana. Prehosp Disaster Med. 2017;32(1):83–93.
To develop a method for selecting health care–associated infection (HAI) measures for public reporting.
Context.
HAIs are common, serious, and costly adverse outcomes of medical care that affect 2 million people in the United States annually. Thirty-seven states have introduced or passed legislation requiring public reporting of HAI measures. State legislation varies widely regarding which HAIs to report, how the data are collected and reported, and public availability of results.
Design.
The Maryland Health Care Commission developed an HAI Technical Advisory Committee (TAC) that consisted of a group of experts in the field of healthcare epidemiology, infection prevention and control (IPC), and public health. This group reviewed public reporting systems in other states, surveyed Maryland hospitals to determine the current state of IPC programs, performed a literature review on HAI measures, and developed six criteria for ranking the measures: impact, unprovability, inclusiveness, frequency, functionality, and feasibility. The committee and experts in the field then ranked each of 18 proposed HAI measures. A composite score was determined for each measure.
Results.
Among outcome measures, the rate of central line–associated bloodstream infections ranked highest, followed by the rate of post–coronary artery bypass grafting surgical-site infections. Among process measures, perioperative antimicrobial prophylaxis, compliance with central-line bundles, compliance with hand hygiene, and healthcare-worker influenza vaccination ranked highest.
Conclusions.
Our qualitative criteria facilitated consensus on the HAI TAC and provided a useful framework for public reporting of HAI measures. Validation will be important for such approaches to be supported by the scientific community.
Certain aspects of sleep co-occur with externalizing behaviours in youth, yet little is known about these associations in adults. The present study: (1) examines the associations between diurnal preference (morningness versus eveningness), sleep quality and externalizing behaviours; (2) explores the extent to which genetic and environmental influences are shared between or are unique to these phenotypes; (3) examines the extent to which genetic and environmental influences account for these associations.
Method
Questionnaires assessing diurnal preference, sleep quality and externalizing behaviours were completed by 1556 young adult twins and siblings.
Results
A preference for eveningness and poor sleep quality were associated with greater externalizing symptoms [r=0.28 (95% CI 0.23–0.33) and 0.34 (95% CI 0.28–0.39), respectively]. A total of 18% of the genetic influences on externalizing behaviours were shared with diurnal preference and sleep quality and an additional 14% were shared with sleep quality alone. Non-shared environmental influences common to the phenotypes were small (2%). The association between diurnal preference and externalizing behaviours was mostly explained by genetic influences [additive genetic influence (A)=80% (95% CI 0.56–1.01)], as was the association between sleep quality and externalizing behaviours [A=81% (95% CI 0.62–0.99)]. Non-shared environmental (E) influences accounted for the remaining variance for both associations [E=20% (95% CI −0.01 to 0.44) and 19% (95% CI 0.01–0.38), respectively].
Conclusions
A preference for eveningness and poor sleep quality are moderately associated with externalizing behaviours in young adults. There is a moderate amount of shared genetic influences between the phenotypes and genetic influences account for a large proportion of the association between sleep and externalizing behaviours. Further research could focus on identifying specific genetic polymorphisms common to both sleep and externalizing behaviours.
Influenza C virus antigen could be detected by immunofluorescence in chick amniotic epithelium 4 hr. after inoculation with undiluted amniotic fluid. Antigen could be detected in the nucleus of rhesus monkey kidney tissue cultures 10 hr. after infection. Only cytoplasmic fluorescence was observed 17–21 hr. after infection.
The pattern of replication was similar to that reported for group I myxoviruses, indicating that the virus is correctly classified as an influenza virus.
Two species of the amphipod Bathyporeia Lindström, B. nana Toulmond and B. sarsi Watkin, have been collected from sand beaches in the Firth of Clyde, both of which appear to be new records for the Clyde Sea area. This may be the first definite record of B. sarsi from the west coast of Britain. In addition, B. nana has been collected from a beach near Oban, Argyll.
The present paper presents a ray analysis for a problem of technical importance in fragmentation studies. The problem is that of suddenly punching a circular hole in either isotropic or transversely isotropic plates subjected to a uniaxial tension field. The ray method, which involves only differentiation, integration, and simple algebra, is shown to be particularly useful in clarifying the propagation process of the resulting unloading waves and obtaining the attendant discontinuities of the various quantities involved. Numerical results obtained from the ray analysis are presented in graphical form and compared with those obtained by more elaborate schemes.
We have evaluated the use of either poly(phenylene) prepared via spin-coatable polymeric precursors or fluorinated polysilynes for optical waveguides. Poly(phenylene) precursors were converted into poly(phenylene) by either curing at 300 °C or by deep-UV exposure in the presence of a photoacid generator. The poly(phenylene)s have a number of desirable properties for optical waveguide applications including good near IR transmission, low dielectric constant, thermal and environmental stability and ease of pattern fabrication using microlithographic techniques. Copolysilynes were spin-coated onto various types of substrates and then exposed by deep-UV radiation. Upon exposure of deep UV irradiation in the presence of air, they undergo photooxidative crosslinking to give insoluble glass-like materials. This photo-oxidation process is accompanied by a large decrease in refractive index from n=1.61 to n= 1.485. The photooxidation results suggest that their potential applications are as photoresists and optical waveguides.
Presented in this paper are justifications for the formal Karal-Keller technique as it applies to propagation, reflection, and transmission of one-dimensional impact waves in nonhomogeneous viscoelastic solids.