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Contemporary readers are most familiar with George Orwell's later works of political satire, such as Animal Farm (1945) and Nineteen Eighty-Four (1949). Less known is the fact that the writer, who is often considered the epitome of ‘Englishness’, was born in India and as a young man served for five years in the Imperial Police in Burma—an experience that reverberated throughout his oeuvre. In Orwell and Empire (Oxford University Press, 2022), Douglas Kerr offers the first comprehensive study of Orwell's writing about the East and of the East in his writing
Biological invasions are among the main threats to global biodiversity and present the potential to disrupt host-parasite dynamics. In Brazil, the scientific reports of the occurrence of the Amazonian fish ‘pirarucu’ (Arapaima gigas) in the upper Paraná River basin, São Paulo state, were made in 2015. However, the effects of its introduction are still unknown, including those associated to its host-parasite relationships. As part of our studies on the possible effects of A. gigas introduction into this basin, the parasites from the eyes of 60 specimens of A. gigas were evaluated. We reported the occurrence of Austrodiplostomum compactum metacercariae (Trematoda, Diplostomidae) parasitizing the eyes of A. gigas supported by morphological and molecular data (COI mtDNA). The new partial sequences had a similarity of 100% to other sequences of Au. compactum previously deposited in Genbank. Five hosts (Prevalence = 8.33%) with a standard length between 69 and 116 cm were infected, with a mean intensity of infection of 31.8 ± 17.2 (1–93). Large infected hosts are unlikely to be a significant prey item for the definitive hosts (medium-sized piscivorous birds), and could act as an ‘ecological sink’, disrupting the transmission of this metacercariae. Hosts with high infection rates by these metacercariae may present cataracts, exophthalmos, and blindness, resulting in loss of visual acuity. Considering that A. gigas is a carnivorous and visual predator, the low infection observed possibly does not act as a biological filter to hinder or contain the invasion, probably presenting a low negative effect on the visual acuity of hosts.
A paleomagnetic study of basaltic lava flows exposed in the northern Neuquén Cordillera, southernmost Central Andes, along the Antiñir-Copahue fault zone (ACFZ), involved 25 sites of the Cola de Zorro Formation (Pliocene–Early Pleistocene) along two different sections. The sites show exclusive normal polarity, corresponding to the Late Pliocene Gauss chron (3.6–2.6 Ma). The angular standard deviation of virtual geomagnetic poles (VGPs; ASD = 14.8°) is consistent with the expected values from recent geomagnetic models, in opposition to anomalously low dispersion found in previous studies in Pleistocene VGPs of reverse polarity from neighboring areas to our study zone. Mean paleomagnetic directions for Bella Vista (Dec = 0.0°, Inc = −50.0°, α₉₅ = 7.6°, K = 36.7, N = 11) and Río Huaraco sections (Dec = 354.9°, Inc = −57.0°, α₉₅ = 7.5°, K = 55.7, N = 8) do not show tectonic rotation around vertical axes. Combining and regrouping our and previous data by area confirmed the absence of tectonic rotations in the Huaraco-Trohunco block and a statistically significant clockwise rotation of 14.4° ± 10.3° of three adjacent tectonic blocks located south of our study locality in Pleistocene times. These results suggest that strike-slip deformation along some sections of the ACFZ was significant in the Pleistocene structural evolution of this region.
Is China part of the world? Based on much of the political, media, and popular discourse in the West the answer is seemingly no. Even after four decades of integration into the global socioeconomic system, discussions of China continue to be underpinned by a core assumption: that the country represents a fundamentally different 'other' that somehow exists outside the 'real' world. Either implicitly or explicitly, China is generally depicted as an external force with the potential to impact on the 'normal' functioning of things. This core assumption, of China as an orientalised, externalised, and separate 'other', ultimately produces a distorted image of both China and the world. This Element seeks to illuminate the ways in which the country and people form an integral part of the global capitalist system. This title is also available as Open Access on Cambridge Core.
Oftentimes, turbulent flows exhibit a high-frequency turbulent component developing on a strong low-frequency periodic motion. In such cases, the low-frequency motion may strongly influence the spatio-temporal features of the high-frequency component. A typical example of such behaviour is the flow around bluff bodies, for which the high-frequency turbulent component, characterized by Kelvin–Helmholtz structures associated with thin shear layers, depends on the phase of the low-frequency vortex-shedding motion. In this paper, we propose extended versions of spectral proper orthogonal decomposition (SPOD) and of resolvent analysis that respectively extract and reconstruct the high-frequency turbulent fluctuation field as a function of the phase of the low-frequency periodic motion. These approaches are based on a quasi-steady (QS) assumption, which may be justified by the supposedly large separation between the frequencies of the periodic and turbulent components. After discussing their relationship to more classical Floquet-like analyses, the new tools are illustrated on a simple periodically varying linear Ginzburg–Landau model, mimicking the overall characteristics of a turbulent bluff-body flow. In this simple model, we in particular assess the validity of the QS approximation. Then, we consider the case of turbulent flow around a squared-section cylinder at a Reynolds number of $Re=22\,000$, for which we show reasonable agreement between the extracted spatio-temporal fluctuation field and the prediction of QS resolvent analysis at the various phases of the periodic vortex-shedding motion.
To identify demographic and clinical characteristics of bipolar depressed patients who require antidepressant (AD) augmentation, and to evaluate the short- and long-term effectiveness and safety of this therapeutic strategy.
Methods
One hundred twenty-two bipolar depressed patients were consecutively recruited, 71.7% of them received mood stabilizers (MS)/second-generation antipsychotics (SGA) with AD-augmentation and 28.3% did not. Patients were evaluated at baseline, and after 12 weeks and 15 months of treatment.
Results
The AD-augmentation was significantly higher in patients with bipolar II compared with bipolar I diagnosis. Patients with MS/SGA + AD had often a seasonal pattern, depressive polarity onset, depressive index episode with anxious features, a low number of previous psychotic and (hypo)manic episodes and of switch. They had a low irritable premorbid temperament, a low risk of suicide attempts, and a low number of manic symptoms at baseline. After 12 weeks of treatment, 82% of patients receiving ADs improved, 58% responded and 51% remitted, 3.8% had suicidal thoughts or projects, 6.1% had (hypo)manic switch, and 4.1% needed hospitalization. During the following 12 months, 92% of them remitted from index episode, 25.5% did not relapse, and 11% needed hospitalization. Although at the start advantaged, patients with AD-augmentation, compared with those without AD-augmentation, did not significantly differ on any outcome as well on adverse events in the short- and long-term treatment.
Conclusion
Our findings indicate that ADs, combined with MS and/or SGA, are short and long term effective and safe in a specific subgroup for bipolar depressed patients.
The water hyacinth grasshopper Cornops aquaticum (Bruner 1906) constitutes an appropriate model to assess phenotypic and karyotypic variability in the context of differentiation and adaptation of insect populations because it occurs over a wide latitudinal range. This study represents a general analysis of phenotype, karyotype and molecular variation in native populations of C. aquaticum in South America. This is also relevant because this insect is considered a promising biological control agent of water hyacinth, a native South American aquatic plant but a pest in South Africa. Along Paraná and Uruguay River Basins, body size correlated negatively with latitude, and positively so with temperature and rainfall in both sexes. To test whether the chromosomal and phenotypic patterns were adaptive, we compared them with neutral microsatellite loci variation in populations from the medium and lower course of the Paraná River. Firstly, the lack of pairwise association between karyotype and phenotype distance matrixes with that of neutral loci suggested non-neutrality. Secondly, phenotypic differentiation for all morphometric traits (PST) was significantly larger than molecular differentiation (FST), indicating a prevailing divergence selection effect on the observed phenotypic patterns. Finally, the phenotypic and genotypic spatial structures – inferred from Bayesian approaches – were discordant: neutral genetic structure clustered together most populations except for the two southernmost, downstream ones, whereas phenotypic spatial structure groups together all the deltaic populations and singles out the two northernmost ones. The results suggest directional selection leading to higher centric fusion frequencies in the downstream populations and favouring morphometric optimal differences in relation to the environment.
Background: Little is known about the modifications in gambling patterns during the Covid-19 pandemic, which has shown signs of increase, particularly for individuals with preexisting gambling problems.
Objectives
Our aim was to assess the behaviour of a cohort of patients in the Trentino Region.
Methods
A semi structured questionnaire containing Hamilton Depression Rating Scale as well as open-ended questions on gambling activities, specifically online gambling, was administred over the telephone. The survey was administred for two months over the lockdown period (april-june 2020) and took approximately 20 minutes to complete.
Results
About 50 responsens were collected. Data are currently been analyzed and will be avaiable at the time of the Congress.
We use the SPace Infrared telescope for Cosmology and Astrophysics (SPICA) project as a template to demonstrate how deep spectrophotometric surveys covering large cosmological volumes over extended fields (1–
$15\, \rm{deg^2}$
) with a mid-IR imaging spectrometer (17–
$36\, \rm{\rm{\upmu m}}$
) in conjunction with deep
$70\, \rm{\rm{\upmu m}}$
photometry with a far-IR camera, at wavelengths which are not affected by dust extinction can answer the most crucial questions in current galaxy evolution studies. A SPICA-like mission will be able for the first time to provide an unobscured three-dimensional (3D, i.e. x, y, and redshift z) view of galaxy evolution back to an age of the universe of less than
$\sim$
2 Gyrs, in the mid-IR rest frame. This survey strategy will produce a full census of the Star Formation Rate (SFR) in the universe, using polycyclic aromatic hydrocarbons (PAH) bands and fine-structure ionic lines, reaching the characteristic knee of the galaxy luminosity function, where the bulk of the population is distributed, at any redshift up to
$z \sim 3.5$
. Deep follow-up pointed spectroscopic observations with grating spectrometers onboard the satellite, across the full IR spectral range (17–
$210\, \rm{\rm{\upmu m}}$
), would simultaneously measure Black Hole Accretion Rate (BHAR), from high-ionisation fine-structure lines, and SFR, from PAH and low- to mid-ionisation lines in thousands of galaxies from solar to low metallicities, down to the knee of their luminosity functions. The analysis of the resulting atlas of IR spectra will reveal the physical processes at play in evolving galaxies across cosmic time, especially its heavily dust-embedded phase during the activity peak at the cosmic noon (
$z \sim 1$
–3), through IR emission lines and features that are insensitive to the dust obscuration.
Overweight is increasing in the adolescent population and became a public health problem in the world. This study aimed to identify the body adiposity indices (BAI) with the best capacity to predict excess fat tissue and propose cut-off points for them, according to sex and adolescence period. This is a cross-sectional study. We calculated BMI, conicity index (CI), BAI, body roundness index (BRI), waist:height ratio (WtHR) and waist:hip ratio. Predictive capacity and cut-off points of adiposity indices were established by ROC (receiver operating characteristic) curves. We determined AUC-ROC and CI, stratified by sex and adolescence period. The best index to identify excess body fat in 10-13-year-old female adolescents was the WtHR (AUC = 0·92), like the BAI in girls aged from 14 to 16 years old (AUC = 0·87) and 17 to 19 years old (AUC = 0·80). In male adolescents aged from 10 to 13 years old and 14 to 16 years old, the best index was the WtHR (AUC = 0·93 and AUC = 0·8, respectively), like the BAI in boys aged from 17 to 19 years old (AUC = 0·95). The use of indices with specific cut-off points for each period of adolescence and according to sex is important for the reliable diagnosis of excess body fat. It is advisable to use indices together to obtain a more accurate assessment. Thus, the WtHR and BAI are reproducible and reliable, with high sensitivity and specificity values, and can be used together with the BMI.
Fe-deficiency anaemia is considered an important public health problem both in wealthier countries and in those of medium and low income, especially in children under 5 years of age. The shortage of studies with national representativity in medium-income countries, such as Brazil, prevents the knowledge of the current situation and its associated factors. We conducted a systematic review and meta-analysis to estimate the pooled prevalence of Fe-deficiency anaemia in Brazilian children under 5 years of age and determined the factors involved in the variability of the estimates of prevalence. We collected fifty-seven studies from the databases MEDLINE, LILACS and Web of Science, along with the reference lists of included articles. We contacted authors for unpublished data. We did not restrict publication timespan and language. This systematic review and meta-analysis was reported according to the guidelines by PRISMA. The pooled prevalence of anaemia in Brazil was 40·2 (95 % CI 36·0, 44·8) %. The age range of the child and the period of data collection were associated with the anaemia prevalence. The pooled prevalence of anaemia was higher in children under 24 months of age (53·5 v. 30·7 %; P < 0·001) and in studies with data collected before 2004 (51·8 v. 32·6 %; P = 0·001). The efforts made by the Brazilian government were successful in the reduction of anaemia in children under 5 years of age in Brazil in the evaluated period. However, prevalence remains beyond acceptable levels for this population group.
To analyse the presence of cardiometabolic risk factors in adolescents with normal-weight obesity (NWO), as well as to investigate health behaviours related to the phenotype.
Design:
The study was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines and the bibliographic search was carried out in the PubMed, Scielo and ScienceDirect databases.
Setting:
School, university and population.
Participants:
Adolescents between 10 and 19 years old.
Results:
A total of eight papers were included. Most studies have found a relationship between NWO and the presence of cardiometabolic risk factors, such as high waist circumference, unfavourable lipid and glycid profile. As for health behaviours, three of the eight studies included evaluated eating habits; however, the results were not conclusive. In addition, four studies analysed the practice of physical activity or physical fitness, which was lower in NWO.
Conclusions:
The available evidence indicates that NWO is related to the early development of cardiometabolic changes, physical inactivity and less physical fitness in adolescents. The results also reveal the importance of early detection of the phenotype, as well as the need for further research on the associated factors to prevent future diseases. Registration (PROSPERO: CRD42020161204).
To propose cut-off points for the TAG–glucose (TyG) index in Brazilian children and evaluate the link to cardiometabolic risk.
Design:
A cross-sectional study with children from a municipality in Minas Gerais, Brazil. Anthropometric (weight, height, waist circumference and waist:height ratio), biochemical (lipid and glucose profile) and blood pressure (BP) tests were performed. Using the receiver operating characteristic curve, cut-off points for the TyG index were proposed according to sex using homoeostasis model of assessment – insulin resistance (IR) as the reference method.
Setting:
Viçosa, MG, Brazil.
Participants:
Children aged 4–9 years (n 515).
Results:
The TyG index cut-off points to identify the risk of IR were 7·9 and 8·1 for boys and girls, respectively. We observed that 48·7 % of the children had an increased TyG index. The increased TyG index was associated with overweight, total body and central fat, increased BP and altered lipid profile. Children with an increased TyG index had a higher accumulation of cardiometabolic risk factors.
Conclusions:
According to the cut-off points proposed by the current study, children at risk of IR estimated by the TyG index presented a higher cardiometabolic risk, including isolated risk factors, as to the higher accumulation of these.
To investigate the association between body image disorders and the lifestyle and body composition of female adolescents.
Design:
Cross-sectional study.
Setting:
The Body Shape Questionnaire (BSQ) and Silhouette Scale and Sociocultural Attitudes Towards Appearance Questionnaire-3 were used to evaluate the participants’ body image. Body composition was evaluated by a Dual-Energy X-ray Absorptiometry equipment, and lifestyles were identified by latent class analysis (LCA) using the poLCA package for R.
Participants:
Female adolescents aged 14–19 years old, in the city of Viçosa-MG, Brazil.
Results:
In total, 405 girls participated in the study. Almost half of the participants were dissatisfied with their current physical appearance (51·4 %), presented body perception distortions (52·9 %). 47·3 % of the adolescents were dissatisfied with their body according to the BSQ, and another 8 % severely so. Subjects with an ‘Inactive and Sedentary’ latent lifestyle were 1·71 times as likely to feel dissatisfied as those with active and sedentary or inactive and non-sedentary lifestyles (95 % CI 1·08, 2·90, P = 0·047). Body image disorders showed an association with decreased amounts of moderate and vigorous physical activity, high screen time, increased alcohol consumption and excess body fat.
Conclusions:
Particular patterns of lifestyle and body composition seem to be associated in female adolescents with dissatisfaction with, distortion of and excessive concern about appearance. Specifically, physical inactivity, sedentary behaviour, alcohol consumption and high body fat percentage may be strongly linked to body image disorders.
This study describes two new species, Trinigyrus anthus n. sp. and Trinigyrus carvalhoi n. sp., from gills of Hypostomus spp. from the Upper Paraná River basin, Brazil. Trinigyrus peregrinus is redescribed based on examination of its holotype, paratypes and new material of specimens parasitizing Pterygoplichthys ambrosettii, also from the Upper Paraná River basin, Brazil. New morphological features were included in the diagnosis of the genus, such as the presence of a sclerotized border on the anchor base, and a weakly sclerotized fringe on the base of the male copulatory organ (MCO). Trinigyrus anthus n. sp. differs from other congeners by the shape of the MCO, presenting an enlarged base with sclerotized fringes resembling flower petals. Trinigyrus carvalhoi n. sp. and T. peregrinus are similar but can be differentiated from each other mainly by the sclerotization of the vagina (absent in the new species), and the morphology of the MCO (C-shaped versus one counterclockwise circle, respectively). For the first time, gene sequences of Trinigyrus spp. from Brazil were obtained (partial ribosomal 28S and mitochondrial cytochrome c oxidase I (mtCOI)). The genetic divergences among the new species and T. peregrinus varied from 2 to 3% (6‒18 pb) based on sequences of 28S ribosomal DNA (rDNA), and 6–7% (83‒92 pb) using mtCOI. Phylogenetic analyses based on partial 28S rDNA revealed that Trinigyrus, Heteropriapulus and Unilatus formed a monophyletic and well-supported clade of monogeneans from Neotropical freshwater loricariids, suggesting a closer relationship among these dactylogyrids and their hosts.
Tibraca limbativentris (Hemiptera: Pentatomidae) is a major pest in Neotropical rice agroecosystems. In autumn–winter, this pest takes refuge in rice stubble and in native vegetation, which allows it to re-colonize the crop during the rice growing season. However, it is still unknown whether this vegetation is a pest sink or is actually a natural trap that contributes to pest population biocontrol. Here we present information on the insect's alternative host plants, a preliminary outline of the relationship between plant phylogeny and insect abundance, and the impact that winter natural enemies have in pest population. Also, we include a proposed methodology for pest density analysis in winter hosts. Our results show significant differences in the abundance/density that T. limbativentris reaches in the 12 host plant species present in our study areas, with a plant-use pattern significantly related to the phylogenetic clade of Poales. Stink bug winter populations mainly comprised diapause adults, and 40% of insect digestive tracts had content. Survival of T. limbativentris was 56.92% in winter hosts. About mortality, 10% was due to undetermined causes and 33.08% due to entomopathogenic fungi, showing a natural regulation of the pest population. Our results suggest that native vegetation impacts winter survival of T. limbativentris. Although these plants offer shelter, they offer a greater contribution to Integrated Pest Management: the natural regulation of winter pest populations through entomopathogenic attack. Further studies on T. limbativentris population dynamics and the preservation of native areas near rice fields will be required for the development of best control practices.
Brightest cluster galaxies (BCGs) residing in cool-core clusters are known to be the stage of intricate baryon cycle phenomena (e.g. gas inflows, AGN outflows, star formation feedback). The scenarios describing the observed properties of these galaxies are still controversial, suffering from limitations due to the spatial resolving power of the instruments, specifically for galaxies beyond the Local Universe. However, the dramatic improvements introduced by the integral-field unit instruments (e.g. MUSE) could shed light on the physical processes driving the evolution of these galaxies. We present an extensive analysis of the stellar and gas properties (i.e. kinematics, stellar mass, star formation rate) of the radio-loud BCG sitting at the centre of the X-ray luminous cool-core cluster Abell 2667 (z = 0.23), based on MUSE data. Our results indicate that the BCG is a massive elliptical, hosting an AGN that is possibly undergoing accretion of cold star-forming clouds of ICM or galactic cannibalism.
Attention is a neurocognitive process composed by subprocesses located in several brain areas and controlled by specific neurotransmitters (Petersen & Posner, 2012). This process aims to select relevant information and modulates sensory processing, perception, memory, and learning. This selection of information processing – based on the combination of perceptual noise exclusion and signal enhancement – is fundamental in developing fine object representations in the brain (see Corbetta & Shulman, 2011; Petersen & Posner, 2012; Roelfsema, van Ooyen, & Watanabe, 2010, for reviews).
Alerting and orienting are the two main processes involved in reading acquisition. Alerting is defined as the multisensory attentional process that increases performance during tasks (Petersen & Posner, 2012), producing a phasic change in alertness (e.g., Ronconi et al., 2016). The alerting system can already be measured in the infant brain (e.g., Ronconi, Facoetti et al., 2014).
To identify the dietary patterns of children aged 4–7 years and verify their association with sociodemographic characteristics, lifestyle habits and exclusive breast-feeding (EBF).
Design
A cross-sectional study nested within a cohort, performed with Brazilian children aged 4–7 years. The children were re-evaluated at age 4 to 7 years and food patterns were identified a posteriori through principal component analysis. The predictive variables were related to socio-economic characteristics, lifestyle habits and duration of EBF.
Setting
Viçosa, Minas Gerais, Brazil.
Participants
Representative sample of 403 children followed up by the Lactation Support Program from the Extension Program of the Universidade Federal de Viçosa during the first 6 months of life.
Results
Five dietary patterns were identified: ‘Traditional’, ‘Unhealthy’, ‘Milk and chocolate’, ‘Snack’ and ‘Healthy’. Children who did not receive EBF until they were at least 4 months old had a higher adherence to the ‘Unhealthy’ and ‘Snack’ patterns, and older children also consumed more ‘Unhealthy’ foods. The highest income was associated with the highest consumption of foods of the patterns ‘Unhealthy’, ‘Milk and chocolate’ and ‘Healthy’.
Conclusions
In view of the results, we emphasize the importance of providing support and encouragement towards EBF in the first months of life, as it can positively influence lifelong eating habits.