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Healthcare provider self-disclosures are common although sometimes controversial. Providers have unique opportunities to self-disclose for the purpose of conveying empathic concern during Dignity Therapy sessions. We examine the topics of empathic self-disclosures (ESDs) during Dignity Therapy sessions.
Methods
We analyzed 203 audio-recorded, transcribed Dignity Therapy sessions from a stepped-wedge, randomized trial of Dignity Therapy led by 14 nurses and chaplains in outpatient palliative care. We extracted 117 ESDs across sessions and applied thematic analysis guided by the constant comparative method to generate ESD topic themes and properties.
Results
Providers disclosed ESDs referring to topics of Relationships and Family, Personal Experiences and Characteristics, Cohort Communalities, Location and Geography, and Values. Though each provider led multiple Dignity Therapy sessions in this dataset, providers rarely disclosed the same information to more than one patient. Some disclosures subtly shifted the patient’s life review. Providers often acknowledged patients that their self-disclosures were not prescribed elements of Dignity Therapy sessions.
Significance of results
Providers engage in ESD across a range of personal topics in a Dignity Therapy context. Some ESD topics overlapped with those considered appropriate in existing health communication literature. Other topics involved complex or underexamined types of disclosures. While self-disclosures appear to be made with empathic intent, providers undermined the impact of some ESDs by portraying them as unprescribed components of the conversation. More research is needed to assess the positive and negative impacts of ESDs during Dignity Therapy and to support augmentation of Dignity Therapy training protocols to account for providers’ ESDs.
Despite the clinical use of dignity therapy (DT) to enhance end-of-life experiences and promote an increased sense of meaning and purpose, little is known about the cost in practice settings. The aim is to examine the costs of implementing DT, including transcriptions, editing of legacy document, and dignity-therapists’ time for interviews/patient’s validation.
Methods
Analysis of a prior six-site, randomized controlled trial with a stepped-wedge design and chaplains or nurses delivering the DT.
Results
The mean cost per transcript was $84.30 (SD = 24.0), and the mean time required for transcription was 52.3 minutes (SD = 14.7). Chaplain interviews were more expensive and longer than nurse interviews. The mean cost and time required for transcription varied across the study sites. The typical total cost for each DT protocol was $331–$356.
Significance of results
DT implementation costs varied by provider type and study site. The study’s findings will be useful for translating DT in clinical practice and future research.
The tools used to evaluate mental health during pregnancy matter. Their efficacy in identifying symptom severity enables better predictions of postpartum mental health. The Mother & Youth: Research on Neurodevelopment & behaviour (MYRNA) cohort is an NIH funded longitudinal cohort from Sherbrooke, Canada studying the effects of pregnant women’s mental health.
Objectives
We examine which mental health tools will better gauge depression and anxiety during pregnancy based on predicting postpartum outcomes. Our hypothesis is that an approach combining a clinical interview with self-report questionnaires may predict mental health in postpartum women.
Methods
Participants’ mental health is evaluated by the SCID-5-RV, a lifetime interview administered at 30 weeks and monthly questionnaires including PHQ-9 and GAD-7. Participants are in the depression/anxiety group if they either pass all the criteria in the SCID during pregnancy or have an average PHQ-9 or GAD-7 score greater than 7. The Edinburgh Postnatal Depression Scale (EPDS) and the Perceived Stress Scale (PSS) are the outcome variables.
Results
PHQ-9 was correlated with EPDS, r(220)= .38, p< .01, and GAD-7 was correlated with PSS, r(213)= .56, p< .01. SCID results only had a significant effect on PSS, F(3,220)= 3.77, p= .01 and not with EPDS, F(3,219)= 1.08, p= .36. When the self-report measures and interview were combined significant effects were seen for both the EPDS, F(1,222)= 18.71, p< .01 and the PSS, F(1,223)= 34.94, p<.01.
Conclusions
Preliminary results show significant associations between measures administered during pregnancy and postpartum measures. Prediction models based on classification will be analyzed once more data is collected.
Dignity therapy (DT) is a guided process conducted by a health professional for reviewing one's life to promote dignity through the illness process. Empathic communication has been shown to be important in clinical interactions but has yet to be examined in the DT interview session. The Empathic Communication Coding System (ECCS) is a validated, reliable coding system used in clinical interactions. The aims of this study were (1) to assess the feasibility of the ECCS in DT sessions and (2) to describe the process of empathic communication during DT sessions.
Methods
We conducted a secondary analysis of 25 transcripts of DT sessions with older cancer patients. These DT sessions were collected as part of larger randomized controlled trial. We revised the ECCS and then coded the transcripts using the new ECCS-DT. Two coders achieved inter-rater reliability (κ = 0.84) on 20% of the transcripts and then independently coded the remaining transcripts.
Results
Participants were individuals with cancer between the ages of 55 and 75. We developed the ECCS-DT with four empathic response categories: acknowledgment, reflection, validation, and shared experience. We found that of the 235 idea units, 198 had at least one of the four empathic responses present. Of the total 25 DT sessions, 17 had at least one empathic response present in all idea units.
Significance of results
This feasibility study is an essential first step in our larger program of research to understand how empathic communication may play a role in DT outcomes. We aim to replicate findings in a larger sample and also investigate the linkage empathic communication may have in the DT session to positive patient outcomes. These findings, in turn, may lead to further refinement of training for dignity therapists, development of research into empathy as a mediator of outcomes, and generation of new interventions.
Dignity Therapy (DT) has been implemented over the past 20 years, but a detailed training protocol is not available to facilitate consistency of its implementation. Consistent training positively impacts intervention reproducibility.
Objective
The objective of this article is to describe a detailed method for DT therapist training.
Method
Chochinov's DT training seminars included preparatory reading of the DT textbook, in-person training, and practice interview sessions. Building on this training plan, we added feedback on practice and actual interview sessions, a tracking form to guide the process, a written training manual with an annotated model DT transcript, and quarterly support sessions. Using this training method, 18 DT therapists were trained across 6 sites.
Results
The DT experts’ verbal and written feedback on the practice and actual sessions encouraged the trainees to provide additional attention to eight components: (1) initial framing (i.e., clarifying and organizing of the patient's own goals for creating the legacy document), (2) verifying the patient's understanding of DT, (3) gathering the patient's biographical information, (4) using probing questions, (5) exploring the patient's story thread, (6) refocusing toward the legacy document creation, (7) inviting the patient's expression of meaningful messages, and (8) general DT processes. Evident from the ongoing individual trainee mentoring was achievement and maintenance of adherence to the DT protocol.
Discussion
The DT training protocol is a process to enable consistency in the training process, across waves of trainees, toward the goal of maintaining DT implementation consistency. This training protocol will enable future DT researchers and clinicians to consistently train therapists across various disciplines and locales. Furthermore, we anticipate that this training protocol could be generalizable as a roadmap for implementers of other life review and palliative care interview-based interventions.
There are sparse data on the outcomes of endoscopic stapling of pharyngeal pouches. The Mersey ENT Trainee Collaborative compared regional practice against published benchmarks.
Methods
A 10-year retrospective analysis of endoscopic pharyngeal pouch surgery was conducted and practice was assessed against eight standards. Comparisons were made between results from the tertiary centre and other sites.
Results
A total of 225 procedures were performed (range of 1.2–9.2 cases per centre per year). All centres achieved 90 per cent resumption of oral intake within 2 days. All centres achieved less than 2-day hospital stays. Primary success (84 per cent (i.e. abandonment of endoscopic stapling in 16 per cent)), symptom resolution (83 per cent) and recurrence rates (13 per cent) failed to meet the standard across the non-tertiary centres.
Conclusion
Endoscopic pharyngeal pouch stapling is a procedure with a low mortality and brief in-patient stay. There was significant variance in outcomes across the region. This raises the question of whether this service should become centralised and the preserve of either tertiary centres or sub-specialist practitioners.
The species of the tree genus Pterospermum Schreb. (Malvaceae: Dombeyoideae) in Malesia are revised. Twenty-six species of Pterospermum are recognised, six of which are new (P. aureum S.K.Ganesan, P. borneense S.K.Ganesan, P. glabrum S.K.Ganesan, P. havilandii S.K.Ganesan, P. merrillianum S.K.Ganesan and P. zollingerianum S.K.Ganesan) and one (P. grewiifolium Pierre) that is a new distributional record for Malesia. Identification keys are provided. All names are typified, and detailed descriptions of all species recognised are provided. Information on habitat, uses and conservation status is given for all species.
This study sought to compare disease recidivism rates between canal wall up mastoidectomy and a canal wall down with obliteration technique.
Methods
Patients undergoing primary cholesteatoma surgery at our institution over a five-year period (2013–2017) using the aforementioned techniques were eligible for inclusion in the study. Rates of discharge and disease recidivism were analysed using chi-square statistics.
Results
A total of 104 ears (98 patients) were included. The mean follow-up period was 30 months (range, 12–52 months). A canal wall down with mastoid obliteration technique was performed in 55 cases and a canal wall up approach was performed in 49 cases. Disease recidivism rates were 7.3 per cent and 16.3 per cent in the canal wall down with mastoid obliteration and canal wall up groups respectively (p = 0.02), whilst discharge rates were similar (7.3 per cent and 10.2 per cent respectively).
Conclusion
Our direct comparative data suggest that canal wall down mastoidectomy with obliteration is superior to a canal wall up technique in primary cholesteatoma surgery, providing a lower recidivism rate combined with a low post-operative ear discharge rate.
The effect of electrostatic microturbulence on fast particles rapidly decreases at high energy, but can be significant at moderate energy. Previous studies found that, in addition to changes in the energetic particle density, this results in non-trivial changes to the equilibrium velocity distribution. These effects have implications for plasma heating and the stability of Alfvén eigenmodes, but make multiscale simulations much more difficult without further approximations. Here, several related analytic model distribution functions are derived from first principles. A single dimensionless parameter characterizes the relative strength of turbulence relative to collisions, and this parameter appears as an exponent in the model distribution functions. Even the most simple of these models reproduces key features of the numerical phase-space transport solution and provides a useful a priori heuristic for determining how strong the effect of turbulence is on the redistribution of energetic particles in toroidal plasmas.
Most of the papers in this volume depend on what has become known as the o-minimal point counting theorem. The aim of this article is to provide enough background in both model theory and number theory for a graduate student in one, but not necessarily both, of these disciplines to be able to understand the statement and the proof of the theorem.
The one dimensional case of the theorem is treated here in full and differs from the original paper ([PW]) in both its number theoretic side (I use the Thue-Siegel Lemma rather than the Bombieri-Pila determinant method) and in its model theoretic side (where the reparametrization of definable functions is made very explicit). The Thue-Siegel method extends easily to the higher dimensional case but, just as in [PW], one has to revert to Yomdin's original inductive argument to extend the reparametrization, and this is only sketched here.
I am extremely grateful to Adam Gutter for typing up my handwritten notes of the Manchester LMS course on which this paper is based. Also, my deepest thanks to Margaret Thomas for so carefully reading the original manuscript. Her numerous suggestions have greatly improved the presentation.
Introduction
So, the aim of these notes is to prove the following:
1.1 Theorem (Pila-Wilkie [PW])
Let S ⊆ Rn be a set definable in some o-minimal expansion of the ordered field of real numbers. Assume that S contains no infinite, semi-algebraic subset. Let ∊ > 0 be given. Then for all sufficiently large H, the set S contains at most H∊ rational points of height at most H.
In July 2013 an LMS-EPSRC Short Instructional Course on ‘O-minimality and diophantine geometry’ was held in the School of Mathematics at the University of Manchester. This volume consists of lecture notes from the courses together with several other surveys. The motivation behind the short course was to introduce participants to some of the ideas behind Pila's recent proof of the André-Oort conjecture for products of modular curves. The underlying ideas are similar to an earlier proof by Pila and Zannier of the Manin-Mumford conjecture (which has in fact long been a theorem, originally due to Raynaud) and combining the results of the various contributions here leads to a proof of this conjecture in certain cases. The basic strategy has three main ingredients: the Pila-Wilkie theorem, bounds on Galois orbits, and functional transcendence results. Each of the topics was the focus of a course. Wilkie discussed o-minimality and the Pila-Wilkie theorem without assuming any background in mathematical logic. (The argument given here is, in fact, slightly different from that given in the original paper, at least in the one-dimensional case.) Habegger's course focused on the Galois bounds and on the completion of the proof (of certain cases of Manin-Mumford) from the various ingredients. And Pila's lectures covered functional transcendence, also touching on various recent related work by Zilber.We have also included some further lecture notes by Wilkie containing a proof of the o-minimality of the expansion of the real field by restricted analytic functions, which is sufficient for the application of Pila-Wilkie to Manin-Mumford. At the short course there were also three guest lectures. Yafaev spoke on very recent breakthroughs on the functional transcendence side in the setting of general Shimura varieties. Masser spoke on some other results (‘relative Manin-Mumford’) that can be obtained by a similar strategy. Jones discussed improvements to the Pila-Wilkie theorem. Unfortunately, Yafaev was unable to contribute to this volume. During the week of the course, tutorials were given by Daw and Orr. For this volume, Orr has written a survey of abelian varieties which contains a proof of the functional transcendence result necessary for the application in Habegger's course.
This collection of articles, originating from a short course held at the University of Manchester, explores the ideas behind Pila's proof of the Andre–Oort conjecture for products of modular curves. The basic strategy has three main ingredients: the Pila–Wilkie theorem, bounds on Galois orbits, and functional transcendence results. All of these topics are covered in this volume, making it ideal for researchers wishing to keep up to date with the latest developments in the field. Original papers are combined with background articles in both the number theoretic and model theoretic aspects of the subject. These include Martin Orr's survey of abelian varieties, Christopher Daw's introduction to Shimura varieties, and Jacob Tsimerman's proof via o-minimality of Ax's theorem on the functional case of Schanuel's conjecture.
Electronic health records (EHRs) may contain infomarkers that identify patients near the end of life for whom it would be appropriate to shift care goals to palliative care. Discovery and use of such infomarkers could be used to conduct effectiveness research that ultimately could help to reduce the monumental cost of caring for the dying. The aim of our study was to identify changes in the plans of care that represent infomarkers, which signal a transition of care goals from nonpalliative care ones to those consistent with palliative care.
Method:
Using an existing electronic health record database generated during a two-year longitudinal study of nine diverse medical–surgical units from four Midwest hospitals and a known group approach, we evaluated patient care episodes for 901 patients who died (mean age = 74.5 ± 14.6 years). We used ANOVA and Tukey's post-hoc tests to compare patient groups.
Results:
We identified 11 diagnoses, including Death Anxiety and Anticipatory Grieving, whose addition to the care plan, some of which also occurred with removal of nonpalliative care diagnoses, represent infomarkers of transition to palliative care goals. There were four categories of patients, those who had: no infomarkers on plans (n = 507), infomarkers added on the admission plan (n = 194), infomarkers added on a post-admission plan (minor transitions, n = 109), and infomarkers added and nonpalliative care diagnoses removed on a post-admission plan (major transition, n = 91). Age, length of stay, and pain outcomes differed significantly for these four categories of patients.
Significance of Results:
EHRs contain pertinent infomarkers that if confirmed in future studies could be used for timely referral to palliative care for improved focus on comfort outcomes and to identify palliative care subjects from data repositories in order to conduct big-data research, comparative effectiveness studies, and health-services research.
To rigorously model fast ions in fusion plasmas, a non-Maxwellian equilibrium distribution must be used. In this work, the response of high-energy alpha particles to electrostatic turbulence has been analyzed for several different tokamak parameters. Our results are consistent with known scalings and experimental evidence that alpha particles are generally well confined: on the order of several seconds. It is also confirmed that the effect of alphas on the turbulence is negligible at realistically low concentrations, consistent with linear theory. It is demonstrated that the usual practice of using a high-temperature Maxwellian, while previously shown to give an adequate order-of-magnitude estimate of the diffusion coefficient, gives incorrect estimates for the radial alpha particle flux, and a method of correcting it in general is provided. Furthermore, we see that the timescales associated with collisions and transport compete at moderate energies, calling into question the assumption that alpha particles remain confined to a flux surface that is used in the derivation of the slowing-down distribution.
The diagnosis of human immunodeficiency virus type 1 (HIV-1)–associated cognitive-motor disorder—either minor cognitive-motor disorder (MCMD) or HIV-1-associated dementia (HAD)—is fraught with potential pitfalls for the clinician. Before making such a diagnosis, clinicians should exclude other etiologies by using neuroimaging, lumbar puncture, and serum chemistries to screen for opportunistic and non-opportunistic infections of the brain and meninges. Clinicians should also consider psychoneurotoxicity (caused from the use of psychoactive substances and prescribed medications) and psychopathology, such as mood, anxiety, and other disorders. In addition, a thorough medical history and physical examination, including a complete neurologic and neuropsychiatric mental status examination, are necessary for an accurate diagnosis. There is also a need for standardized neuropsychological and functional status tests, since the diagnostic criteria for these disorders are partly based on these criteria. Treatment targets should include subclinical cognitive-motor impairment and neuroprotection, as well as MCMD and HAD. Currently, zidovudine remains the best proven treatment for these disorders, but other nucleoside reverse transcriptase inhibitors, as well as nonnucleoside reverse transcriptase inhibitors and protease inhibitors, show promise, and selected agents from these classes are being tested in clinical trials. Other areas that should be investigated are the modulation of inflammatory mediators (such as tumor necrosis factor α), neurotransmitter manipulation (especially of dopamine), and nutritional interventions.
Increasing numbers of young people experience disruption to their schooling owing to chronic illness. Absence from the day-to-day life of their school for prolonged or accumulative periods of time can erode their sense of belonging and create anxiety about falling behind academically. Maintaining positive connections to school can meet their desire for normalcy and realisable educational goals. Part of a project called Link ‘n’ Learn, funded by an Australian Research Council Linkage grant (2008–2010), this in-depth qualitative case study of 22 participants — senior secondary students and their mathematics teachers — investigated academic continuity: students’ access to and utilisation of opportunities to learn effectively so that academic progress is made despite disruption to full-time schooling. The students experienced diverse types of chronic illness, medical interventions, and patterns of absence from school. They all sought to continue their school studies. Their teachers highlighted surprise, concern and discomfort related to students studying during serious illness, and school workload issues. Ambiguities about educational responsibility for students during absence were widespread. Teachers demonstrated hesitance to initiate contact with students, but students nevertheless expressed their desire for teachers to remain involved with them. Implications for the educational support of young people with chronic illness are presented.