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In the quest for human rights justice for communities and workers whose rights are breached by transnational businesses, non-judicial mechanisms (NJMs) are often deployed, but how effective are they? This book creates a blueprint for reforming transnational human rights NJMs and for helping communities and workers to use them. Through 587 interviews with 1100 individuals over five years of research in Indonesia and India, the authors delve into the practical workings of NJMs in diverse industries and contexts. The findings reveal that while NJMs are limited in providing standalone remedies, they can play a valuable role within a broader regulatory ecosystem. Combining rich empirical data, multi-method analyses and a new theoretical framework, the authors argue for a multi-pronged approach to human rights redress. Their findings will advance both academic and policy debates about the merits and shortcomings of NJMs.
The Bronze Age of Greece was unknown until the end of the nineteenth century, when Heinrich Schliemann's excavations stunned the world by bringing to light the glamour of Mycenaean elite society. This book, by one of Greece's most distinguished archaeologists, provides a complete introduction to Mycenaean life and archaeology. Through both chronological and thematic chapters, it examines the main Mycenaean centres, the palaces and kingship, the social structure, writing, religion and its political implications, and the contacts and relations of the Mycenaeans with neighbouring countries, especially Asia Minor, Egypt, the coast of Syria–Palestine, and Italy. Attention is paid to the distinctive Mycenaean art, including monumental architecture, gold and silver metalwork, and jewellery, and the book is supported by over 300 colour illustrations. Dora Vassilikou concludes by examining the simultaneous catastrophes that brought the Bronze Age of the Eastern Aegean to its end and opened up a new era.
Research suggests that those caring for a loved one with an eating disorder in the UK report unmet needs and highlight areas for improvement. More research is needed to understand these experiences on a wider, national scale.
Aims
To disseminate a national survey for adults who had experience caring for a loved one with an eating disorder in the UK, informed by the findings of a smaller scale, qualitative study with parents, siblings and partners in the UK.
Method
A cross-sectional web-based survey was disseminated to adults who had experience caring for a loved one with an eating disorder in the UK.
Results
A total of 360 participants completed the survey. Participants described experiences of care received in both children and young people's, and adult services. Those receiving care from children and young people's services generally reported more timely care, greater involvement in care and more confidence managing their loved one's symptoms post-discharge. In both settings, participants identified a number of areas for improvement, including more timely access to care, improved transition processes and discharge planning, and increased involvement in their loved one's care.
Conclusions
This survey captures the experiences of individuals caring for a loved one with an eating disorder in the UK. There are identified discrepancies between experiences of care in children and young people services compared with adult services. Clinical implications and recommendations for improvement are discussed, including improved transition and discharge processes, increased involvement of and/or support for carers themselves, and more timely access to support services for the unwell individual.
Since the end of World War II, the US government has spent nearly $4 trillion on humanitarian, economic, and military assistance to other countries. Despite the myriad benefits of such programs, mass support has long been lacking. Here, I argue that low citizen trust in government can help us to understand why. Using cross-sectional and panel survey data from the United States, I find a positive and substantively significant relationship between political trust and support for government spending on foreign aid. Overall, these findings underscore the relevance of political trust and further illustrate the drivers of U.S. public opinion toward foreign aid, something that has implications for whether America should turn inward or continue its long-standing role of global leadership.
Pulmonary atresia with intact ventricular septum is a rare congenital cardiac lesion with significant anatomical heterogeneity. Surgical planning of borderline cases remains challenging and is primarily based on echocardiography. The aim was to identify echocardiographic parameters that correlate with surgical outcome and to develop a discriminatory calculator.
Methods:
Retrospective review of all pulmonary atresia with intact ventricular septum cases at a statewide tertiary paediatric cardiac centre was performed between 2004 and 2020. Demographic, clinical, and echocardiographic data were collected. Logistic regression was used to develop a discriminatory tool for prediction of biventricular repair.
Results:
Forty patients were included. Overall mortality was 27.5% (n = 11) and confined to patients managed as univentricular (11 vs 0, p = 0.027). Patients who underwent univentricular palliation were more likely to have an associated coronary artery abnormality (17 vs 3, p = 0.001). Fifteen surviving patients (51.7%) achieved biventricular circulation while 14 (48.3%) required one-and-a-half or univentricular palliation. Nineteen patients (47.5%) underwent percutaneous pulmonary valve perforation. No patients without tricuspid regurgitation achieved biventricular repair. The combination of tricuspid valve/mitral valve annulus dimension ratio and right ventricle/left ventricle length ratio identified biventricular management with a sensitivity of 93% and specificity of 96%. An online calculator has been made available.
Conclusion:
Pulmonary atresia with intact ventricular septum is a challenging condition with significant early and interstage morbidity and mortality risk. Patient outcomes were comparable to internationally reported data. Right ventricle/left ventricle length and tricuspid valve/mitral valve annulus dimension ratios identified a biventricular pathway with a high level of sensitivity and specificity. Absent tricuspid regurgitation was associated with a univentricular outcome.
Between 1956 and 1957, four Broadway producers–Cheryl Crawford, Roger L. Stevens, Robert E. Griffith, and Harold S. Prince–working in different configurations, each crucially impacted West Side Story’s development. Recognized then and retrospectively as a huge gamble for anyone involved, these four producers arrived at the project from different career stages and positions of financial security, which ultimately decided who could reasonably take a gamble on bringing a musical drama to Broadway. Here I survey different ways these producers helped birth West Side Story, such as providing dramaturgical advice, securing backers, coordinating a difficult casting process, and identifying productive tryout venues. These producers’ struggles with West Side Story’s innovations also signaled necessary evolution in established practices such as the backers’ audition. Placing these producers’ work on West Side Story in the context of their career trajectories will reinforce the role of timing and good fortune to any musical’s potential success.
Women have long been underrepresented in American politics. This is evidenced by women being less likely to run for and hold elected office. Existing scholarship largely focuses on explaining why women are less politically ambitious than their male counterparts but pays less attention to why some women do run for office. To this end, I focus on the potential role of labor union membership. I argue that labor unions can foster political ambition and increase ordinary people’s likelihood of running for office. I test this among women in the American mass public, primarily with survey data from the 2010–22 Cooperative Election Study (CES). Overall, I find that labor union membership is significantly associated with women’s likelihood of running for office. I also find that this robust relationship is unlikely to be driven by self-selection or omitted variable biases. Overall, these findings help us to better understand the sources of political ambition, illustrate a viable potential pathway to boost women’s likelihood of seeking elected office, and underscore the political consequences of organized labor.
The role of the sarcopenic obesity (SO) phenotype for disease risk prediction has been tested in several observational studies, but results have been contrasting due to the application of different diagnostic models(1–3). This study applies the newly proposed the European Society for Clinical Nutrition and Metabolism (ESPEN)-European Association for the Study of Obesity (EASO) definition of SO(4) to a representative population of adults aged 50 years and older to evaluate its performance in the identification of prevalent cases of SO and its association with measures of cognitive function.
Data from individuals aged 50-85 years was collected from the National Health and Nutrition Examination Survey 1999-2002 waves. At the screening phase of the SO definition following the definition of the European Society for Clinical Nutrition and Metabolism and the European
Association for the Study of Obesity (ESPEN-EASO), body mass index and waist circumference were used to evaluate obesity, while sarcopenia cases were identified using the SARC-F questionnaire (a self-report questionnaire to screen sarcopenia). Sarcopenia was diagnosed based on knee extensor isometric strength per weight (KES/W) and a percentage of appendicular lean mass per weight, while fat mass percent measured by Dual-energy X-ray absorptiometry was used to determine obesity. Cognitive function in older participants was assessed using the Digit Symbol Substitution Test (DSST), while memory-related question was used for middle-aged individuals or older participants without DSST scores.
Participants aged 50–85 years were men (44.7%) with a mean age of 66.7 years, and most participants aged 60 years and over (87.4%). The prevalence of SO was 32.5%, 20.9% and 15.3% at screening, diagnosis phase I, and diagnosis phase II of the ESPEN-EASO definition, respectively. The prevalence of cognitive impairment was 14.8% in participants aged 50-59 years and 29.5% in participants aged 60-85 years. There were associations between SO and cognitive impairment at diagnosis phase I (Odds ratio (OR): 1.6, 95%CI (confidence interval) 1.1-2.4) and phase II (OR: 1.9, 95%CI 1.1-3.3). These associations were significant among participants aged 60-85 years (phase I, OR: 2.2, 95%CI 1.4-3.4; phase II, OR: 2.8, 95%CI 1.6-4.8), but not among those aged 50-59 years.
The new ESPEN-EASO definition of SO identified a high prevalence of SO cases. A significant association between SO and poor cognitive function in older individuals was observed.
Governments all over the world have transitioned away from directly providing public services to contracting and collaborating with cross-sectoral networks to deliver services on their behalf. Governments have thus pursued an array of policy instruments to improve interorganizational progress towards policy goals. In recent years, outcomes-based contracting has emerged as a compelling solution to service quality shortcomings and collective action challenges. Informed by public policy, public administration, and public procurement scholarship, this Element details the evolution of social outcomes in public contracting, exploring the relationship between how outcomes are specified and managed and how well such instruments deliver against policy goals. It comments on the possible drawbacks of contracting for social outcomes, highlighting how governments may use outcomes as an excuse to avoid actively managing contracts or to sidestep their accountability as outlined in public law. This title is also available as Open Access on Cambridge Core.
With its linguistic and cultural diversity, Austronesia is important in the study of evolutionary forces that generate and maintain cultural variation. By analysing publicly available datasets, we have identified four classes of cultural features in Austronesia and distinct clusters within each class. We hypothesized that there are differing modes of transmission and patterns of variation in these cultural classes and that geography alone would be insufficient to explain some of these patterns of variation. We detected relative differences in the verticality of transmission and distinct patterns of cultural variation in each cultural class. There is support for pulses and pauses in the Austronesian expansion, a west-to-east increase in isolation with explicable exceptions, and correspondence between linguistic and cultural outliers. Our results demonstrate how cultural transmission and patterns of variation can be analysed using methods inspired by population genetics.
Clinical trials often struggle to recruit enough participants, with only 10% of eligible patients enrolling. This is concerning for conditions like stroke, where timely decision-making is crucial. Frontline clinicians typically screen patients manually, but this approach can be overwhelming and lead to many eligible patients being overlooked.
Methods:
To address the problem of efficient and inclusive screening for trials, we developed a matching algorithm using imaging and clinical variables gathered as part of the AcT trial (NCT03889249) to automatically screen patients by matching these variables with the trials’ inclusion and exclusion criteria using rule-based logic. We then used the algorithm to identify patients who could have been enrolled in six trials: EASI-TOC (NCT04261478), CATIS-ICAD (NCT04142125), CONVINCE (NCT02898610), TEMPO-2 (NCT02398656), ESCAPE-MEVO (NCT05151172), and ENDOLOW (NCT04167527). To evaluate our algorithm, we compared our findings to the number of enrollments achieved without using a matching algorithm. The algorithm’s performance was validated by comparing results with ground truth from a manual review of two clinicians. The algorithm’s ability to reduce screening time was assessed by comparing it with the average time used by study clinicians.
Results:
The algorithm identified more potentially eligible study candidates than the number of participants enrolled. It also showed over 90% sensitivity and specificity for all trials, and reducing screening time by over 100-fold.
Conclusions:
Automated matching algorithms can help clinicians quickly identify eligible patients and reduce resources needed for enrolment. Additionally, the algorithm can be modified for use in other trials and diseases.
Increased rehabilitation intensity, the number of minutes of therapy per day, is associated with improved outcomes. However, it is unclear whether males and females receive the same inpatient stroke rehabilitation intensity. A sub-analysis of a retrospective population-based cohort study of adults (5877 females, 6893 males) with stroke discharged to inpatient rehabilitation between 2017 and 2021 was conducted. The mean rehabilitation intensity was 75.86 min/day for males and 73.33 min/day for females (p < .0001). Males <80 years of age were more likely to receive higher rehabilitation intensity than females. Future research should explore what factors account for this sex difference.
This chapter offers a ‘realist’ interpretation of the All-Affected Principle, as a democratic principle for distributing political inclusion. This interpretation aims to capture the AAP’s democratic appeal as a basis for political legitimacy in the pluralist institutional landscape of global governance practice. First, it is argued that the distinctive democratic value of the AAP derives from its concern with institutionally empowering those valuable dimensions of individuals’ political agency that are expressed through participation in the practical performance of global governance functions, alongside those expressed through deliberative or aggregative social ‘choice’ procedures. Second, it is argued that this interpretation of the normative point of the AAP supports a pluralist, rather than a cosmopolitan, institutional approach to democratic inclusion: the sites, types, and constituencies of inclusion should vary across institutional contexts, depending on their real-world consequences for the empowerment of individuals’ capacities to advance their interests through institutional collaboration with others. Third, the chapter elaborates the broader ‘realist’ conceptions of global democracy and political legitimacy that are implied by this interpretation of the AAP, and highlights some advantages and limitations of the realist account.
Caroline Randall Williams’ 2019 collection reorients the biographical speculation surrounding the ‘Dark Lady’ sonnets toward the woman who has been advanced as their inspiration, focusing on her instead of on Shakespeare, to help embody black women’s often-obscured history in the west.
This article reviews the development of mental health and psychiatric services in Australia for the international reader. The development of relevant legislation, health-care systems, and the effectiveness of treatment for people with schizophrenia is reviewed. Gaps in service delivery and future directions are considered.
In this chapter we examine a number of present-day varieties of Scots and Scottish Standard English (SSE). We begin by describing the Scots–SSE continuum, with its roots in earlier socio-cultural developments. We then turn to the present day, examining the attitudes towards different varieties of Scots across geographic and social dimensions. The main part of the chapter focuses on recent research on the many varieties of Scots, providing a detailed picture of the phonological and morphosyntactic forms found therein. In terms of phonology, Scots and SSE overlap, but remain divergent, especially given a number of phonological changes in Scots over the twentieth century, and continued Scots regional variation. The analysis of morphosyntax shows a core of forms shared across most varieties, including SSE, and these are largely stable. A number of other ‘home-grown’ forms are increasing in use across Scotland. Overall, our analysis shows that Scots is maintaining its own distinctive pathway in the twenty-first century.
Benghal dayflower and sicklepod are weeds of economic importance in peanut in the southeastern United States due to their extended emergence pattern and limited effective herbicides for control. Field studies were conducted near Jay, Florida, in 2022 and 2023, to evaluate the effect of planting date and herbicide combinations on Benghal dayflower and sicklepod control in peanut crops. Peanut planted in June was exposed to a higher Benghal dayflower density than peanut planted in May. Sicklepod density was similar between May and June planting dates at 28 d after preemergence and early postemergence herbicide applications, but density was greater in peanut that was planted in June, 28 d after the mid-postemergence application. A preemeergence herbicide application followed by (fb) an early postemergence application of S-metolachlor or diclosulam + S-metolachlor controlled Benghal dayflower 84% to 93% 28 d after early postemergence in peanut that was planted in May, but control was reduced to 58% to 78% in the crop that had been planted in June. Regardless of planting date, a preemeergence application fb S-metolachlor or diclosulam + S-metolachlor applied early postemergence provided <80% sicklepod control 28 d after early postemergence. Imazapic + dimethenamid-P + 2,4-DB applied postemergence improved Benghal dayflower control to at least 94% 28 d after mid-postemergence, but sicklepod control was not >85%. Regardless of the planting date, paraquat + bentazon + S-metolachlor applied early postemergence was required to achieve ≥95% sicklepod control. However, herbicide combinations that included paraquat + bentazon + S-metolachlor reduced peanut yield when planting was delayed to June. In fields that are infested with Benghal dayflower and sicklepod, it is recommended that peanut be planted in early May to minimize the potential impact of these weeds and to increase peanut yield. Late-planted peanut required more intensive herbicide applications to obtain the same peanut yield as the May-planted peanut.
Hunting, habitat loss and fragmentation have caused a rapid decline in the distribution and abundance of the clouded leopard Neofelis nebulosa across its range, and in several areas, including Taiwan, the species is now extirpated. Taiwan, a former stronghold for the species, is a candidate for its reintroduction, based on increasing prey abundance and high forest coverage. Such future reintroduction efforts, however, are hampered by a lack of analysis of potential clouded leopard habitat on the island. To address this, we explore habitat suitability for the species in Taiwan. We used a multi-scale, multivariate habitat selection model based on clouded leopard presence–absence data from extensive camera-trap surveys across its current range to predict suitable habitat in Taiwan. Our findings indicate that 38% of Taiwanese territory is potentially suitable habitat for the clouded leopard, of which 46% is under protection. This demonstrates the high potential of Taiwan's habitat for clouded leopard reintroduction.