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The phenomenon of near-death experiences (NDEs) has fascinated humanity for centuries but remains famously difficult to define and study. This book presents a unique source, integrating historical, clinical, psychological, and neuroscientific approaches toward a modern scientific understanding of NDEs. Featuring exciting clinical and experimental details about processes in dying brains, it examines the physiological and psychological underpinnings of this extraordinary phenomenon. Chapters offer science-based accounts of NDEs as a natural part of the human condition informed by our biology and the remarkable capacities of the brain. By proposing that the origin of NDEs can be found in the physiology-dependent mental processes of the experiencer as expressed in altered states of consciousness, this book provides up-to-date insights for psychologists, psychiatrists, neuroscientists, and philosophers alike.
In this study, Steven Kepnes constructs a 'positive' Jewish theology, one that gives expression to God's nature and powers and that opposes 'apophatic' Holocaust and postmodern theologies that deny the ability of language to express God's nature. Drawing from the Pentateuch, Prophets, and Jewish prayer, Kepnes also uses methods from medieval philosophy, analytic philosophy, and hermeneutics. From medieval philosophy and the Bible, Kepnes develops what he calls a 'soft' metaphysics with principles of God and the revealed Torah at its center. Identifying a fundamental contradiction between the transcendent God of philosophy and the personal God of the Bible, he demonstrates how analytic philosophy, Jewish hermeneutics, and Jewish liturgy offer constructive strategies to negotiate this contradiction. Kepnes also argues that Jewish theology can neither remain in the domain of metaphysics nor the nature of God, but must turn toward the practical and ethical. He concludes with a call for a prophetic theological ethics to address the pressing issue of climate change.
From First Job to Career is an anthology that weaves together inspiring first-job stories from people across diverse industries and backgrounds, offering career seekers of all ages the chance to connect with relatable experiences and hard-earned wisdom. This collection reveals the different paths people take in shaping their careers and serves as a resource for readers to identify with and learn from others' journeys. Paired with a comprehensive review of research in vocational psychology and career counseling, the book distills key principles and provides actionable resources for navigating the job search and building a meaningful career.
Are you a medical student preparing for the UKMLA exam? Look no further than The UKMLA Applied Knowledge Test: Clinical Presentations and Conditions. This comprehensive revision guide is an essential resource for any student looking to succeed in the exam. The text follows the General Medical Council's exam content map, covering all of the clinical presentations and conditions listed as being required for the examination. The text is further organised by 18 areas of clinical practice, each led by a specialist in the relevant field. The book features over 450 colour illustrations, and follows an easy to read, consistent layout throughout. Each topic covers clinical examination, diagnosis, management, treatment options and more. An essential preparation guide for UK based medical students, and students sitting the PLAB examination.
The Senate majority and minority leaders stand at the pinnacle of American national government – as important to Congress as the speaker of the House. However, the invention of Senate floor leadership has, until now, been entirely unknown. Providing a sweeping account of the emergence of party organization and leadership in the US Senate, Steering the Senate is the first-ever study to examine the development of the Senate's main governing institutions. It argues that three forces – party competition, intraparty factionalism, and entrepreneurship – have driven innovation in the Senate. The book details how the position of floor leader was invented in 1890 and then strengthened through the twentieth and twenty-first centuries. Drawing on the full history of the Senate, this book immediately becomes the authoritative source for understanding the institutional development of the Senate – uncovering the origins of the Senate party caucuses, steering committees, and floor leadership.
During the past decade, mathematics education has changed rapidly, giving rise to a polarization of opinions among the community of research mathematicians. What is the appropriate balance between theory, technique, and applications? What is the role of technology? How do we fulfil the needs of students entering other fields? The purpose of this volume, the proceedings of a conference held at the Mathematical Sciences Research Institute in Berkeley in 1996, is to present a serious discussion of these educational issues, with a balanced representation of opposing ideas. Part I deals with general issues in university mathematics education; Part II presents case studies on particular projects; Part III presents a range of opinions on mathematics education in elementary and secondary schools; and Part IV presents the reports of the working groups.
How did Donald Trump become the preeminent figure in American politics over the past decade, and why has the Democratic Party struggled to extinguish his threat despite his unpopularity and the unpopularity of his policies? The answer lies in an area that liberal political strategists have not focused on and political scientists have neglected: the politics of dominance. While twenty-first-century liberals have focused on offering more attractive policies, illiberal leaders such as Trump have grasped that politics is a dominance competition. “High-dominance” leaders strive to make opinion, embrace us-versus-them framing, double down on provocative statements and positions, stay on the offensive, take risks, and use entertaining, provocative language. “Low-dominance” leaders study polls and tell voters what they think they want to hear, fear “othering” opponents, walk back or qualify controversial statements, play defense, abhor risk, and use bromidic language. Restoring the dominance advantage the Democrats enjoyed at times during the twentieth century is a key to defeating Trumpism.
Although the interaction between humans and their environments is central to psychological science, its dynamics throughout the lifespan remain unexplored. We consider how ecological affordances—the opportunities and threats an environment poses for one’s goal achievement—can be differently perceived across developmental life stages. Integrating affordance-management and life-history perspectives, we propose that individuals perceive and respond to ecological affordances based on their prioritized goals, which shift systematically as they progress through life stages. The same environment can be perceived as posing an opportunity at one life stage, but as posing a threat or being irrelevant at other stages with different goal priorities. To illustrate the value of this framework, we focus on three environmental dimensions tied to recurring adaptive challenges in human history: genetic relatedness, physical violence, and sex-age ratio. We examine how individuals perceive and navigate ecological affordances across three key life stages—childhood, mating, and parenting—through multiple strategies: (a) recalibrating cognitive and affective attunement to relevant cues, (b) adjusting psychological and behavioral strategies, and (c) reconstructing their environments at various levels. By bridging social, developmental, and cognitive psychology with behavioral ecology and evolutionary biology, this framework advances our understanding of human-environment interactions by (a) challenging the assumption that environmental effects are static, (b) generating precise hypotheses about psychological and behavioral patterns, enabling systematic and holistic investigation, and (c) underscoring the potential for lifelong flexibility in ecological navigation.
It remains unclear which individuals with subthreshold depression benefit most from psychological intervention, and what long-term effects this has on symptom deterioration, response and remission.
Aims
To synthesise psychological intervention benefits in adults with subthreshold depression up to 2 years, and explore participant-level effect-modifiers.
Method
Randomised trials comparing psychological intervention with inactive control were identified via systematic search. Authors were contacted to obtain individual participant data (IPD), analysed using Bayesian one-stage meta-analysis. Treatment–covariate interactions were added to examine moderators. Hierarchical-additive models were used to explore treatment benefits conditional on baseline Patient Health Questionnaire 9 (PHQ-9) values.
Results
IPD of 10 671 individuals (50 studies) could be included. We found significant effects on depressive symptom severity up to 12 months (standardised mean-difference [s.m.d.] = −0.48 to −0.27). Effects could not be ascertained up to 24 months (s.m.d. = −0.18). Similar findings emerged for 50% symptom reduction (relative risk = 1.27–2.79), reliable improvement (relative risk = 1.38–3.17), deterioration (relative risk = 0.67–0.54) and close-to-symptom-free status (relative risk = 1.41–2.80). Among participant-level moderators, only initial depression and anxiety severity were highly credible (P > 0.99). Predicted treatment benefits decreased with lower symptom severity but remained minimally important even for very mild symptoms (s.m.d. = −0.33 for PHQ-9 = 5).
Conclusions
Psychological intervention reduces the symptom burden in individuals with subthreshold depression up to 1 year, and protects against symptom deterioration. Benefits up to 2 years are less certain. We find strong support for intervention in subthreshold depression, particularly with PHQ-9 scores ≥ 10. For very mild symptoms, scalable treatments could be an attractive option.
We solve a Bayesian inverse Navier–Stokes (N–S) problem that assimilates velocimetry data by jointly reconstructing a flow field and learning its unknown N–S parameters. We devise an algorithm that learns the most likely parameters of a Carreau shear-thinning viscosity model, and estimates their uncertainties, from velocimetry data of a shear-thinning fluid. We conduct a magnetic resonance velocimetry experiment to obtain velocimetry data of an axisymmetric laminar jet in an idealised medical device (US Food and Drug Administration’s benchmark nozzle) for a blood analogue fluid. The algorithm successfully reconstructs the flow field and learns the most likely Carreau parameters. Predictions from the learned model agree well with rheometry measurements. The algorithm accepts any differentiable algebraic viscosity model, and can be extended to more complicated non-Newtonian fluids (e.g. Oldroyd-B fluid if a viscoelastic model is incorporated).
Endometrial receptivity to human embryo implantation can be simply defined as the ability for the maternal endometrium to support appropriate attachment, invasion, and maintenance of the early human embryo. In contrast to the simplicity of definition, understanding the mechanisms involved in early human embryo implantation are severely limited due to differences between humans and experimental animals, as well as ethical, moral, and technological barriers to direct observation of human implantation in vivo and ex vivo. There is no doubt, however, that the human endometrium has a limited temporal window of receptivity during which normal embryo implantation can occur, and that this time window is largely driven by the action of progesterone. Given the critical nature of endometrial receptivity and implantation in fertility and pregnancy health, it remains an important area of study despite the barriers. This chapter reviews our understanding of endometrial receptivity as gleaned from animal studies, observational studies in women attempting conception with or without medical assistance, and limited experimental studies in women undergoing assisted reproduction. We conclude the chapter with a brief description and appraisal of proposed clinical testing for altered receptivity.
This article is part of an ongoing series at The Asia-Pacific Journal commemorating the sixtieth anniversary of the start of the US-Korean War.
Amidst the chaos surrounding North Korea's military offensive in the summer of 1950, the United Nations Security Council passed a series of resolutions which gave the United States-led United Nations Command (UNC) sanction to occupy the Korean peninsula. A crucial element of the work of this occupation – the second of southern Korea since 1945 – dealt with refugees. By August 1950, as the territory under United Nations Command jurisdiction shrank and came to centre around the Kyŏngsang provinces, South Korean authorities reported that the northern advance had displaced well over one million people.
Japan has not only suffered from dismal macroeconomic performance over the past two decades, but it has lost its edge in areas of its greatest competitive strength, such as electronics, especially information and communications technology (ICT) hardware Japanese electronics firms have declined by many standard measures of industrial performance, such as market share, exports, and profits.
[Japan's payments towards the UN budget, at more than 19 per cent, are second only to the US. Although all its efforts thus far to secure a permanent seat on the Security Council have been in vain, many Japanese citizens serve, some at high levels, on UN bodies. None has been more prominent than Sadako Ogata, Head of the United Nations High Commission for Refugees through the decade of the 1990s.
Biological flyers and swimmers navigate in unsteady wake flows using limited sensory abilities and actuation energies. Understanding how vortical structures can be leveraged for energy-efficient navigation in unsteady flows is beneficial in developing autonomous navigation for small-scale aerial and marine vehicles. Such vehicles are typically operated with constrained onboard actuation and sensing capabilities, making energy-efficient trajectory planning critically important. This study finds that trajectory planners can leverage three-dimensionality appearing in a complex unsteady wake for efficient navigation using limited flowfield information. This is revealed with comprehensive investigations by finite-horizon model-predictive control for trajectory planning of a swimmer behind a cylinder wake at Reynolds number of 300. The navigation performance of three-dimensional cases is compared with scenarios in a two-dimensional (2-D) wake. The underactuated swimmer is able to reach the target by leveraging the background flow when the prediction horizon exceeds one-tenth of the wake-shedding period, demonstrating that navigation is feasible with limited information about the flowfield. Further, we identify that the swimmer can leverage the secondary transverse vortical structures to reach the target faster than is achievable navigating in a 2-D wake.
Using the dual-pathway framework (Beach et al., 2022a), we tested a Neuro-immune Network (NIN) hypothesis: i.e., that chronically elevated inflammatory processes may have delayed (i.e., incubation) effects on young adult substance use, leading to negative health outcomes. In a sample of 449 participants in the Family and Community Health Study who were followed from age 10 to age 29, we examined a non-self-report index of young adult elevated alcohol consumption (EAC). By controlling self-reported substance use at the transition to adulthood, we were able to isolate a significant delayed (incubation) effect from childhood exposure to danger to EAC (β = −.157, p = .006), which contributed to significantly worse aging outomes. Indirect effects from danger to aging outcomes via EAC were: GrimAge (IE = .010, [.002, .024]), Cardiac Risk (IE = −.004, [−.011, −.001]), DunedinPACE (IE = .002, [.000, .008]). In exploratory analyses we examined potential sex differences in effects, showing slightly stronger incubation effects for men and slightly stronger effects of EAC on aging outcomes for women. Results support the NIN hypothesis that incubation of immune pathway effects contributes to elevated alcohol consumption in young adulthood, resulting in accelerated aging and elevated cardiac risk outcomes via health behavior.