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The TIE (Tractatus de Intellectus Emendatione) is an early, unfinished text that first appeared in the Opera posthuma. There is strong evidence that it was mostly written before Ep6 and the KV (Mignini ) and that it was, perhaps, intended as a methodological companion to that metaphysical work. Spinoza was familiar with the methodological works of Aristotle and Bacon. Descartes, however, in some ways provided the closest model for Spinoza’s project. Like Descartes’ Discourse on Method which accompanied scientific works illustrating the method, the TIE begins with an inspiring autobiographical story about redirecting one’s life toward the pursuit of the highest good. The TIE even more closely follows the model of Descartes’s similarly titled Rules for the Direction of the Native Intellect. Like Spinoza’s TIE, that methodological work was left unfinished and unpublished in the author’s lifetime, but it is likely that Spinoza had access to it (Marion ). The project of the TIE is, as the title suggests, to emend or purify the intellect of distractions resulting from the pursuit of sensual pleasure, honor, wealth, and so on.
Thought is an attribute of God (E2p1) endowed, like every attribute, with infinite and finite modes that are conceived through it (E1def5, E1p16, E2a2). Thought and the related concept of knowledge were important categories in the philosophical theories that Spinoza set out to supplant. Spinoza’s treatment of thought poses some of the most difficult problems for interpreters of his philosophy. These problems are of especially great importance because Thought, as an essence of infinite substance, is arguably the single most fundamental category in his metaphysics and epistemology.
One of the most interesting and important axioms employed by Spinoza in the Ethics is the so-called ‘causal axiom,’ E1a4: “Effectus cognitio a cognitione causae dependet, & eandem involvit,” which is plausibly translated as “Cognition of an effect depends on, and involves, cognition of its cause.” The Latin word cognitio can also be translated as “knowledge,” if the word is understood in a broad sense that includes items that do not meet the high standards explained in E2p40s2, for example. In that passage, cognitio is applied to the first kind of knowledge, that is, random sensory perception, as well as to higher-grade cognition of the second and third kinds. In the causal axiom, the interplay among the concepts of cause and effect, involvement, and dependence here at the beginning of the Ethics partly shapes our understanding of some crucial features of Spinoza’s philosophy.
Descartes, philosopher, mathematician, and scientist, was one of most influential thinkers in seventeenth- and eighteenth-century Europe. Born in France, Descartes produced his most famous works while living at various addresses in Holland. His opposition to traditional Aristotelian teachings met with official disapproval, but his work was widely read and discussed. Spinoza engaged in writing with Descartes’s thought more than he did with any other near contemporaries. The early TIE is similar in its overall plan to Descartes’s Discourse on Method (1637) and to the earlier, unpublished Rules for the Direction of the Native Intelligence which circulated widely and might have been read by Spinoza.
Confusion characterizes ideas commonly found in the human mind. Although all ideas are true as related to God (E2p32), human ideas most often lack truth, adequacy, and other epistemological virtues. Spinoza variously characterizes these philosophically defective ideas as fictional, false, mutilated, and confused. These defects are all closely related; this article focuses specifically on confusion.
The necessity (necessitas) of all things is one of the most distinctive features of Spinoza’s philosophy. For those opposed to Spinoza it is, along with the treatment of God, its most notorious feature. In the Ethics, it is proclaimed and explained in various places. One main point is that God, the only substance, exists necessarily (E1p7d, E1p11). A second main point is that nothing exists apart from God and what is is conceived through God (E1p14–15), but what is conceived through God “follows [sequi]” from God: “From the necessity of the divine nature there must follow infinitely many things in infinitely many modes, (i.e., everything which can fall under an infinite intellect)” (E1p16). In this passage, the scope of the “everything” characterizing what falls under the infinite intellect seems to be everything without qualification, leaving no room for anything to not follow from God. Moreover, God is the cause of everything (E1p16c1), and E1a3 tells us, “From a given determinate cause the effect follows necessarily; and conversely, if there is no determinate cause, it is impossible for an effect to follow” (emphasis added).
The Andromeda galaxy (M 31) has experienced a tumultuous merger history as evidenced by the many substructures present in its inner halo. We use planetary nebulae (PNe) as chemodynamic tracers to shed light on the recent merger history of M 31. We identify the older dynamically hotter thicker disc in M 31 and a distinct younger dynamically colder thin disc. The two discs are also chemically distinct with the PN chemodynamics implying their formation in a ‘wet’ major merger (mass ratio ∼ 1:5) ∼ 2.5–4.5 Gyr ago. From comparison of PN line-of-sight velocities in the inner halo substructures with predictions of a major-merger model in M 31, we find that the same merger event that formed the M 31 thick and thin disc is also responsible for forming these substructures. We thereby obtain constraints on the recent formation history of M 31 and the properties of its cannibalized satellite.
Synchronized cardioversion is an internationally accepted standard therapy for unstable tachyarrhythmias, but it is conventionally an in-hospital physician-led intervention. Increasingly, it is being brought forward into the prehospital setting as part of a specialist paramedic scope of practice; however, very little literature exists regarding the epidemiology or efficacy in this setting.
Methods:
All patients receiving cardioversion within a United Kingdom (UK) ambulance service were identified using an electronic database. The period of inclusion was March 1, 2017 through October 31, 2020. These data were then interrogated to provide demographic, physiological, and efficacy data, and then a sub-group was created to identify those who presented with a primary arrhythmia (as opposed to post-cardiac arrest).
Results:
From a total of 93 patients, prehospital synchronized cardioversion successfully terminated the tachyarrhythmia in 96% of patients presenting with a primary arrhythmia (85% in the allcomers group) with a predominance towards males (82% of patients) and an average age of 67 years. Hypotension and reduced level of consciousness were the most commonly documented unstable features (84.4% and 44.4%).
Conclusion:
Cardioversion within a paramedic-led service results in efficacy rates of 96% in patients presenting with a primary tachyarrhythmia. This is a similar efficacy rate to traditional doctor-led therapies. Demographic data show that males make up over 80% of the patient population, in keeping with previously published work across the spectrum of cardiac interventions.
Typhlocoelum cucumerinum is a tracheal parasite of birds widely distributed across the globe. Nevertheless, aspects of the biology of this cyclocoelid are still poorly understood. Herein, we report the finding of T. cucumerinum in definitive and intermediate hosts from an urban waterbody of Brazil. The parasite was initially detected during the necropsy of domestic Muscovy ducks (Cairina moschata) found dead in the locality. Coproparasitological tests in live animals revealed that 12/47 (25.53%) Muscovy ducks and 2/8 (25%) mallards (Anas platyrhynchos platyrhynchos) were infected with T. cucumerinum. Moreover, rediae and metacercariae morphologically similar to T. cucumerinum were found in 3/248 (1.33%) Biomphalaria straminea collected in the same waterbody frequented by the birds. The conspecificity between the adult and the larval stages was confirmed molecularly (100% similarity in Cox-1). Moreover, the phylogenetic position of T. cucumerinum was determined for the first time based on partial fragments of the 28S, Cox-1 and Nad-1 genes. The species grouped with other members of the subfamily Typhlocoelinae with sequences available, but the data obtained do not support the distinctiveness of the genera Typhlocoelum and Tracheophilus. Further studies involving a broader range of species can result in taxonomic rearrangements in Typhlocoelinae.
The correspondence between Leibniz and Arnauld was judged by Leibniz himself to be very useful for understanding his philosophy. Historians have concurred in this judgment. Leibniz did not find any philosophy of independent interest in the letters Arnauld sent him. Historians have, for the most part, also concurred in this finding. I shall argue that on one set of issues at least — modal metaphysics and free will — Arnauld accomplished more than facilitating Leibnizian elucidations. He held his own in this dispute. Indeed, were it not for the general sophistication and superior handling of such issues as identity, unity, and the nature of body enjoyed by the Leibnizian system, the Cartesian position on modal metaphysics and free will espoused by Arnauld might have won the day in the eyes of later philosophers. A proper appreciation of the Cartesian framework should also make it of considerable interest to philosophers presently at work on the metaphysics of modality. I shall argue that Descartes and some Cartesians like Arnauld espoused a strongly actualist doctrine. This means they thought that all philosophically interesting uses of possibles were analyzable into facts about actually existing things.
The Elizabethan Court poet Edward de Vere has, since 1920, lived a notorious second, wholly illegitimate life as the putative author of the poems and plays of William Shakespeare. The work reconstructs Oxford’s life, assesses his poetic works, and demonstrates the absurdity of attributing Shakespeare’s works to him. The first documentary biography of Oxford for over seventy years, Monstrous Adversary seeks to measure the real Oxford against the myth. Impeccably researched and presenting many documents written by Oxford himself, Nelson’s book provides a unique insight into Elizabethan society and manners through the eyes of a man whose life was privately scandalous and richly documented.
Despite a growing body of literature on integrated land–sea management (ILSM), very little critical assessment has been conducted in order to evaluate ILSM in practice on island systems. Here we develop indicators for assessing 10 integrated island management principles and evaluate the performance of planning and implementation in four island ILSM projects from the tropical Pacific across different governance structures. We find that where customary governance is still strongly respected and enabled through national legislation, ILSM in practice can be very effective at restricting access and use according to fluctuations in resource availability. However, decision-making under customary governance systems may be vulnerable to mismanagement. Government-led ILSM processes have the potential to design management actions that address the spatial scale of ecosystem processes and threats within the context of national policy and legislation, but may not fully capture broad stakeholder interests, and implementation may be poorly coordinated across highly dispersed island archipelagos. Private sector partnerships offer unique opportunities for resourcing island ILSM, although these are highly likely to be geared towards private sector interests that may change in the future and no longer align with community and/or national objectives. We identify consistent challenges that arise during island ILSM planning and implementation and offer recommendations for improvement.
Comparison of histories of great earthquakes and accompanying tsunamis at eight coastal sites suggests plate-boundary ruptures of varying length, implying great earthquakes of variable magnitude at the Cascadia subduction zone. Inference of rupture length relies on degree of overlap on radiocarbon age ranges for earthquakes and tsunamis, and relative amounts of coseismic subsidence and heights of tsunamis. Written records of a tsunami in Japan provide the most conclusive evidence for rupture of much of the plate boundary during the earthquake of 26 January 1700. Cascadia stratigraphic evidence dating from about 1600 cal yr B.P., similar to that for the 1700 earthquake, implies a similarly long rupture with substantial subsidence and a high tsunami. Correlations are consistent with other long ruptures about 1350 cal yr B.P., 2500 cal yr B.P., 3400 cal yr B.P., 3800 cal yr B.P., 4400 cal yr B.P., and 4900 cal yr B.P. A rupture about 700–1100 cal yr B.P. was limited to the northern and central parts of the subduction zone, and a northern rupture about 2900 cal yr B.P. may have been similarly limited. Times of probable short ruptures in southern Cascadia include about 1100 cal yr B.P., 1700 cal yr B.P., 3200 cal yr B.P., 4200 cal yr B.P., 4600 cal yr B.P., and 4700 cal yr B.P. Rupture patterns suggest that the plate boundary in northern Cascadia usually breaks in long ruptures during the greatest earthquakes. Ruptures in southernmost Cascadia vary in length and recurrence intervals more than ruptures in northern Cascadia.
A 30 ka paleo-climate record of the Boise area, Idaho, USA has been delineated using groundwater stable isotopic compositions. Groundwater ages are modern (cold batholith), 5–15 ka (thermal batholith), 10–20 ka (frontal fault), and 20–30 ka (Snake River plain thermal). The stable isotopic composition of groundwaters have been used as a surrogate for the stable isotopic composition of precipitation. Using δ2H and δ18O compositions, local groundwater lines (LGWL's) were defined for each system. Each LGWL has been evaluated with defined slopes of 6.94 and 8, respectively, and resulting deuterium excess values (d) were found for each groundwater system for each slope. Time dependent changes in moisture source humidity and temperature, and Boise area recharge temperatures, calculated from stable isotopic data and the deuterium excess factors, agree with previous paleo-climate studies. Results indicate that from the last glacial maximum to the present time the humidity over the ocean moisture source increased by 9%, sea surface temperature at the moisture source increased 6–7°C, and local Boise temperature increased by 4–5°C. A greater increase of temperature at the moisture source as compared to the Boise area may impart be due to a shift in the moisture source area.
Timpanogos Cave, located near the Wasatch fault, is about 357 m above the American Fork River. Fluvial cave sediments and an interbedded carbonate flowstone yield a paleomagnetic and U–Th depositional age of 350 to 780 ka. Fault vertical slip rates, inferred from calculated river downcutting rates, range between 1.02 and 0.46 mm yr− 1. These slip rates are in the range of the 0–12 Ma Wasatch Range exhumation rate (∼ 0.5–0.7 mm yr− 1), suggesting that the long-term vertical slip rate remained stable through mid-Pleistocene time. However, the late Pleistocene (0–250 ka) decelerated slip rate (∼ 0.2–0.3 mm yr− 1) and the accelerated Holocene slip rate (∼ 1.2 mm yr− 1) are consistent with episodic fault activity. Assuming that the late Pleistocene vertical slip rate represents an episodic slowing of fault movement and the long-term (0–12 Ma) average vertical slip rate, including the late Pleistocene and Holocene, should be ∼ 0.6 mm yr− 1, there is a net late Pleistocene vertical slip deficit of ∼ 50–75 m. The Holocene and late Pleistocene slip rates may be typical for episodes of accelerated and slowed fault movement, respectively. The calculated late Pleistocene slip deficit may mean that the current accelerated Wasatch fault slip rate will extend well into the future.
Peaty, tidal-marsh soils interbedded with estuarine mud in late Holocene stratigraphic sequences near Coos Bay, Oregon, may have been submerged and buried during great (M > 8) subduction earthquakes, smaller localized earthquakes, or by nontectonic processes. Radiocarbon dating might help distinguish among these alternatives by showing that soils at different sites were submerged at different times along this part of the Cascadia subduction zone. But comparison of conventional 14C ages for different materials from the same buried soils shows that they contain materials that differ in age by many hundreds of years. Errors in calibrated soil ages represent about the same length of time as recurrence times for submergence events (150–500 yr)—this similarity precludes using conventional 14C ages to distinguish buried soils along the southern Oregon coast. Accelerator mass spectrometer 14C ages of carefully selected macrofossils from the tops of peaty soils should provide more precise estimates of the times of submergence events.
We describe bright microwave events that were first detected with the Parkes 64-m telescope at 8.4 or 22 GHz from six active-chromosphere stars. In some flares spectral data were obtained over a large frequency range from simultaneous measurements with the Parkes reflector (8.4 or 22 GHz), the Tidbinbilla interferometer (8.4 and 2.29 GHz), the Fleurs synthesis telescope (1.42 GHz) and the Molonglo Observatory synthesis telescope (0.843 GHz). Data on circular polarization were obtained from the Parkes observations at 8.4 GHz.
The stars were in a wide variety of evolutionary states, ranging from a single pre-main-sequence star (HD 36705), two RS CVn binaries (HD 127535, HD 128171), an Algol (HD 132742) and two apparently single K giants (HD 32918 and HD 196818). Their high brightness temperatures, positive spectral indices and low polarization are consistent with optically thick gyrosynchrotron emission from mildly relativistic electrons with average energies 0.5 to 3 MeV gyrating in inhomogeneous magnetic fields of 5 to 100 G.
Very sensitive low-noise amplifiers designed to receive transmissions from spacecraft are not necessarily suitable receivers for radio astronomy. In the former case a good signalto- noise ratio is required so that high data rates can be achieved. In the latter the ratio of signal to noise power may be as low as 10-4 and the stability of receiver gain and that of ail sources of noise during long integration times become of equal importance.
This paper describes a novel solution to the problem, which allowed important astronomy to be performed while the ruby maser receivers belonging to the European Space Agency were installed on the Parkes radio telescope for an extended period of time.