We present a re-discovery of G278.94+1.35a as possibly one of the largest known Galactic supernova remnants (SNRs) – that we name Diprotodon. While previously established as a Galactic SNR, Diprotodon is visible in our new Evolutionary Map of the Universe (EMU) and GaLactic and Extragalactic All-sky MWA (GLEAM) radio continuum images at an angular size of $3{{{{.\!^\circ}}}}33\times3{{{{.\!^\circ}}}}23$, much larger than previously measured. At the previously suggested distance of 2.7 kpc, this implies a diameter of 157$\times$152 pc. This size would qualify Diprotodon as the largest known SNR and pushes our estimates of SNR sizes to the upper limits. We investigate the environment in which the SNR is located and examine various scenarios that might explain such a large and relatively bright SNR appearance. We find that Diprotodon is most likely at a much closer distance of $\sim$1 kpc, implying its diameter is 58$\times$56 pc and it is in the radiative evolutionary phase. We also present a new Fermi-LAT data analysis that confirms the angular extent of the SNR in gamma rays. The origin of the high-energy emission remains somewhat puzzling, and the scenarios we explore reveal new puzzles, given this unexpected and unique observation of a seemingly evolved SNR having a hard GeV spectrum with no breaks. We explore both leptonic and hadronic scenarios, as well as the possibility that the high-energy emission arises from the leftover particle population of a historic pulsar wind nebula.

Both the quantity and quality of the maternal language input are important for early language development. However, depression and anxiety can negatively impact mothers’ engagement with their infants and their infants’ expressive language abilities. Australian mother-infant dyads (N = 30) participated in a longitudinal study examining the effect of maternal language input when infants were 24 and 30 months and maternal depression and anxiety symptoms on vocabulary size. Half the mothers had elevated depression and anxiety symptoms during at least one point in the study (at 6, 12, 18, 24, or 30 months). The results showed that only maternal input measures (word tokens, types, and mean length of utterance) predicted vocabulary size. While no evidence was found that brief periods of maternal depression and anxiety negatively impacted early vocabulary development, the findings highlight the critical importance and possible mitigating effects of maintaining good quality mother–infant interactions during early development.

An examination of all coronavirus disease 2019 (COVID-19) cases and patient movements in Geneva indicated important disease activity within the healthcare system since the beginning of the pandemic. We estimate that 4.3% of all COVID-19 cases were likely acquired within the healthcare system, contributing to 62% of the COVID-19–related deaths.

The long-term prospective multi-centre nationwide (French) observational study FRANCISCO will provide new information on perimembranous ventricular septal defect with left ventricular overload but no pulmonary hypertension in children older than 1 year. Outcomes will be compared according to treatment strategy (watchful waiting, surgical closure, or percutaneous closure) and anatomic features of the defect. The results are expected to provide additional guidance about the optimal treatment of this specific population, which is unclear at present.

The European Network for Health Technology Assessment (EUnetHTA) organizes an annual Forum with stakeholders to receive feedback on its activities, processes, and outputs produced. The fourth edition of the EUnetHTA Forum brought together representatives of HTA bodies, patient organizations, healthcare professionals (HCPs), academia, payers, regulators, and industry. The aim of this paper is to provide an overview of the highlights presented at the 2019 EUnetHTA Forum, reporting the main items and themes discussed in the plenary panel and breakout sessions. The leading topic was the concept of unmet medical need seen from different stakeholders' perspectives. Breakout sessions covered the joint production of assessment reports and engagement with payers, patients, and HCPs. Synergies, pragmatism, and inclusiveness across Member States and stakeholders were emphasized as leading factors to put in place a collaboration that serves the interest of patients and public health in a truly European spirit.

The Neolithisation of Europe involved socio-economic and biological adaptations to new environments. The use of seaweed as livestock fodder, for example, was key to the introduction of animal husbandry to the Orkney archipelago, c. 3500 cal BC. Using stable isotope analysis of faunal remains from Skara Brae, this study provides new evidence for, and clarifies the chronology of, the adoption of seaweed consumption by sheep. The results show that sheep consumed moderate amounts of seaweed from the moment of their introduction to Orkney—a practice that facilitated the successful spread of the farming lifeways to the most remote areas of Europe.

A lasting legacy of the International Polar Year (IPY) 2007–2008 was the promotion of the Permafrost Young Researchers Network (PYRN), initially an IPY outreach and education activity by the International Permafrost Association (IPA). With the momentum of IPY, PYRN developed into a thriving network that still connects young permafrost scientists, engineers, and researchers from other disciplines. This research note summarises (1) PYRN’s development since 2005 and the IPY’s role, (2) the first 2015 PYRN census and survey results, and (3) PYRN’s future plans to improve international and interdisciplinary exchange between young researchers. The review concludes that PYRN is an established network within the polar research community that has continually developed since 2005. PYRN’s successful activities were largely fostered by IPY. With >200 of the 1200 registered members active and engaged, PYRN is capitalising on the availability of social media tools and rising to meet environmental challenges while maintaining its role as a successful network honouring the legacy of IPY.

The purpose was to assess the psychometric properties of the French version of the Young Schema Questionnaire - Short Form 3 (YSQ–S3). The main non-clinical sample (N = 605, M = 20.63, 78% women) was divided into two subsamples: One was used for exploratory factor analyses (EFA) and the other was used for confirmatory analyses. Next, internal consistency, convergent validity and criterion-related validity were studied. The EFA to each of the five domains was similar to the theoretical structure postulated by Young. The confirmatory analysis of each of the five domains appeared to favor our solution over a single-factor solution and Young’s solution. The confirmatory factor analyses of high-order structures did not give fully satisfactory results but appeared to favor our solution (RMSEA =.11, CFI =.76, TLI =.71, SRMR =.07, AIC = 58,566.44). In our best model, the reliability (> .70) was satisfactory for fourteen schemas. The relationships between the schemas and the neuroticism, extraversion and psychoticism scores went in the expected directions. Detrimental parental rearing behaviors were linked to high scores for the various schemas. Lastly, 4 schemas differentiated between the clinical and non-clinical groups. In conclusion, the overall psychometric qualities of the French version of the YSQ–S3 allow its use in clinical populations.

The development of sustainable farming systems depends on our ability to predict and manage the response of weed communities to changes in cropping practices. A study was established at Normandin, Québec, Canada, to investigate the influence of liquid dairy manure and mineral fertilizer, as well as chisel and moldboard plow tillage systems, in a spring barley monoculture and a 3-yr spring barley-forage rotation that included red clover and timothy. Weed species richness (Margalef's DMG), evenness (Shannon's E), and diversity (Shannon's H') were examined in these treatments from 1992 to 1995. Nutrient source had no effect on any of the three diversity indices. Evenness values were extremely low in all years, suggesting dominance of a few weed species in most treatments. Weed species richness and diversity generally were greater in the barley-forage rotation compared with the monoculture. Tillage effects on richness and diversity varied with crop rotation. Margalef's DMG and Shannon's H' were greater in 1993 and 1995, but they were lower in 1994 when chisel was compared with moldboard plowing in the monoculture. In 1994, chickweed density was about five times greater in the chisel-plowed monoculture compared with other treatment combinations of rotation and tillage. In 1995, only one species with a density of six plants m−2 occurred in the moldboard-plowed monoculture compared with three to six species and densities of 51 to 832 plants m−2 in the other rotation by tillage treatments. Climatic conditions and herbicide use patterns in the different crop rotation treatments may have contributed to the more dynamic nature of weed species diversity in the barley monoculture. Reduced frequency of tillage and herbicide application; management of the forage stands, especially with regard to their termination; and improved soil resource availability likely explained the increased but more stable diversity of the weed communities in the barley-forage rotation.

The presence of volunteer canola is becoming a significant agro-ecological concern, given the large-scale use of herbicide-tolerant varieties in some areas. Our goal was to estimate the frequency and persistence of volunteer canola in Québec cropping systems by surveying fields that included a single canola crop since 1995. A survey was conducted in 131 fields in the main canola-growing areas of Québec: in the Saguenay-Lac Saint-Jean region and the Québec City–La Pocatière area. Volunteer canola plants were counted in 0.25-m2 quadrats every 10 m along a W pattern, and every 15 m along the margins of 88 fields. Volunteer canola plants were found in 90% of the fields surveyed and in a wide range of crops, including cereal, corn, and soybean. Average densities of 4.9 and 3.9 plants/m2 were found 1 yr after canola production in fields and field margins, respectively. Volunteer canola densities decreased significantly over time. However, volunteer plants were still present at low densities 4 and 5 yr after production. Dense stands of volunteer canola were found before postemergence herbicide application in no-till fields (9.8 ± 4.1 plants/m2), suggesting that, contrary to what was suggested in the literature, seeds could become dormant in no-till as well as in tilled systems. A small proportion of the volunteer canola plants observed in no-till fields near Québec City and Ottawa included plants that had overwintered, either originating from fall-germinated seedlings, harvested adult plants that had grown new leaves before the onset of winter, or spring regrowth from the base of unharvested adult plants from experimental plots. The presence and persistence of low densities of volunteer canola may not have been a cause of concern until now. However, producers should be made more aware of the potential short-and long-term problems associated with potential gene flow between different herbicide-tolerant canola (HT canola) varieties and also between HT canola and related weed species.

Lithostratigraphic and palynological analysis of two cores recovered from the ‘Grand Lac’ (New Caledonia), combined with 35 14C AMS dates, yields a paleoenvironmental record spanning the last 2000 yr. The lithology is represented mainly by clayey or laminated layers. A catastrophic event, which is marked by very coarse deposits, occurred probably between ca 1070–960 cal yr B.P. and possibly is associated with an unusually severe La Niña event. Before and after this event, a similar combination of the two main sediment types is recorded. The repeated alternation of laminated and clayey layers is interpreted as the response to local hydrologic forcing, which may reflect a shift from relatively wet to relatively drier conditions, respectively. Variable amount of micro-charcoal is detected all along the profile. Without additional evidence, notwithstanding the initial local human settlement documented since ca 2900 14C yr B.P., micro-charcoal occurrence and variability cannot be linked directly to an anthropogenic origin. No distinct palynological zonations in relation to the lithology are observed, and the vegetation changes may only represent minor transitions across environmental limits.

Multiproxy analysis of three littoral cores from western New Caledonia supports the hypothesis that the main controlling factors of environmental changes are sea-level change, ENSO variability and extra-tropical phenomena, such as the Medieval Warm Period (MWP) marked by a tendency for La Niña-like conditions in the tropical Pacific. The record starts during the late Holocene sea-level rise when the terrestrial vegetation indicated wet and cool conditions. The site was a coastal bay definitely transformed into a freshwater swamp at around 3400 cal yr BP, after the rapid drawdown of sea level to its current level. Sediments and foraminiferal assemblages indicated subsequent episodes of freshwater infillings, emersion or very high-energy conditions, likely related to climatic changes and mostly controlled by ENSO variability. Between 2750 and 2000 cal yr BP, relatively dry and cool climate prevailed, while wetter conditions predominated between ca. 1800 and 900 cal yr BP. The Rhizophoraceae peak between ca. 1080 and 750 cal yr BP, coeval with the MWP, may indicate a global phenomenon. Microcharcoal particles present throughout the record increased after 1500 cal yr BP, suggesting an anthropogenic source. From ca. 750 cal yr BP the appearance of current type of vegetation marks the human impact.