We highlight the historical and contemporary policies that govern paleontological research on federally recognized Native American lands. The United States has a long history of fossil dispossession from Indigenous Peoples, and federal policies surrounding the management of Native American lands (i.e., reservations), and the geological resources therein, have changed through time. These changes reflect shifting popular and political ideologies regarding Native American nations’ sovereignty and self-governance. As of 2022, the United States has a government-to-government relationship with federally recognized Tribal entities, but that has not always been the case. Historians have divided post-contact Native American federal policy into distinct eras: Colonial Times to 1820, Native American Removal and Reservation (1820–1887), Allotments and Attempted Assimilation (1887–1934), Reorganization and Preservation (1934–1953), Termination and Relocation (1953–1968), and Tribal Self-Determination (1968–present). Documentation of how the federal policies from each of these eras continue to impact current paleontological research is limited. We summarize major legislative actions, court cases, and historical events that have affected paleontological resource management in Native American territory. We use this historical context to identify federal policy gaps and highlight legal nuances associated with fossil collection and ownership, particularly given the importance of fossils to some Native Americans’ cultural patrimony. Finally, we explore how these gaps affect scientific research and highlight best practices for conducting paleontological research on vertebrate, invertebrate, and paleobotanical body and trace fossils using the CARE (Collective Benefit, Authority to Control, Responsibility, Ethics) Principles for Indigenous Data Governance (https://www.gida-global.org/care).

Redcanyonite (IMA2016-082), (NH4)2Mn[(UO2)4O4(SO4)2](H2O)4, occurs underground in the Blue Lizard mine, Red Canyon, White Canyon district, San Juan County, Utah, USA. It occurs with natrozippeite, brochantite, devilline, posnjakite, johannite, gypsum, bobcookite, pickeringite, pentahydrite and the NH4-analogue of zippeite: ammoniozippeite. Redcanyonite occurs as radial aggregates of red–orange needles and blades individually reaching up to 0.2 mm long, with aggregates measuring up to 1 mm in diameter. Crystals are flattened on {010} and elongated along [100], exhibit perfect cleavage on {010}, and exhibit the forms {010}, {001}, {101} and {10$\bar{1}$}. Twinning is ubiquitous, by 180° rotation on [100]. Redcanyonite is translucent with a pale orange streak, is non-fluorescent, has a Mohs hardness of 2, and has brittle tenacity with uneven fracture. Optically, redcanyonite is biaxial (+), α = 1.725(3), β = 1.755(3), γ = 1.850(5) (white light); 2V (meas.) = 60(2)°, 2V (calc.) = 61.3°; and dispersion is r < v, very strong. Pleochroism is: X = orange, Y = yellow and Z = orange; Y << X < Z. The optical orientation is X = b, Y ≈ c*, Z ≈ a. The empirical formula is (NH4)2.02(Mn0.49Cu0.09Zn0.06)Σ0.64H+0.72[(UO2)4O4(S0.99P0.01O4)2](H2O)4, based on 4 U and 24 O apfu. Redcanyonite is monoclinic, C2/m, a = 8.6572(17), b = 14.155(3), c = 8.8430(19) Å, β = 104.117(18)°, V = 1050.9(4) Å3 and Z = 2. The structure was refined to R1 = 0.0382 for 1079 reflections with Iobs > 3σI. Uranyl oxo-sulfate sheets in redcanyonite adopt the well-known zippeite topology, which consists of zigzag chains of uranyl pentagonal bipyramids linked by sulfate tetrahedra to form sheets. The sheets are linked to each other through bonds to interlayer NH4+ groups and octahedrally coordinated Mn2+, and by hydrogen bonds from H2O groups. Redcanyonite is named for Red Canyon in southeast Utah, USA.

Leószilárdite (IMA2015-128), Na6Mg(UO2)2(CO3)6·6H2O, was found in the Markey Mine, Red Canyon, White Canyon District, San Juan County, Utah, USA, in areas with abundant andersonite, natrozippeite, gypsum, anhydrite, and probable hydromagnesite along with other secondary uranium minerals bayleyite, čejkaite and johannite. The new mineral occurs as aggregates of pale yellow bladed crystals flattened on ﹛001﹜ and elongated along [010], individually reaching up to 0.2 mmlong. More commonly it occurs as pale yellow pearlescent masses to 2 mm consisting of very small plates. Leószilárdite fluoresces green under both longwave and shortwave ultraviolet light, and is translucent with a white streak, hardness of 2 (Mohs), and brittle tenacity with uneven fracture. The new mineral is readily soluble in room temperature H2O. Crystals have perfect cleavage along ﹛001﹜, and exhibit the forms ﹛110﹜,﹛001﹜,﹛100﹜,﹛101﹜ and ﹛101﹜. Optically, leószilárdite is biaxial (-), α= 1.504(1), β= 1.597(1), γ= 1.628(1) (white light); 2V (meas.) = 57(1)°, 2V (calc.) = 57.1°; dispersion r > v, slight. Pleochroism: X= colourless, Y and Z= light yellow; X<Y ≈ Z The average of six wavelength dispersive spectroscopic analyses provided Na2O 14.54, MgO 3.05, UO3 47.95, CO2 22.13, H2O 9.51, total 97.18 wt.%. The empirical formula is Na5.60Mg0.90U2O28C6H12.60, based on 28 O apfu. Leószilárdite is monoclinic, C2/m, a = 11.6093(21), b = 6.7843(13), c = 15.1058(28) Å, β = 91.378(3)°, V= 1189.4(4) Å3 and Z = 2. The crystal structure (R1 = 0.0387 for 1394 reflections with Iobs > 4σI), consists of uranyl tricarbonate anion clusters [(UO2)(CO3)3]4- held together in part by irregular chains of NaO5(H2O) polyhedra sub parallel to [010]. Individual uranyl tricarbonate clusters are also linked together by three-octahedron units consisting of two Na-centred octahedra that share the opposite faces of a Mg-centred octahedron at the centre (Na–Mg–Na), and have the composition Na2MgO12(H2O)4. The name of the new mineral honours the Hungarian-American physicist, inventor and biologist Dr. Leó Szilárd (1898–1964).

Pronamide [3,5-dichloro-N-(1,1-dimethyl-2-propynyl)benzamide] inhibited root and shoot growth, but had little effect on the germination of oat (Avena sativa L.) or cucumber (Cucumis sativus L.), and sprouting of quackgrass [Agropyron repens (L.) Beauv.] buds. Root growth was more sensitive than shoot growth. Pronamide decreased the longitudinal growth rate and caused radial enlargement in the elongation region of the roots of oat seedlings within 4 hr. Dry weights of the swollen root tips increased 6% over the controls after 4 hr. Pronamide stopped the growth of established oat plants within 24 hr when added to nutrient culture medium. It caused a slight increase in 86Rb uptake by excised oat roots. Pronamide stopped normal mitosis in treated oat roots within 0.5 hr. Examination of treated root tips under a microscope showed numerous cells in arrested metaphase, c-pairs, multinucleate cells, polyploidy and swollen and misshapen nuclei. Incorporation of 14C-glucose into oat root cell walls and 14C-leucine into protein were increased by 26 and 20% respectively, following 4-hr incubations in pronamide. The primary mode of action of pronamide is mitotic poisoning.

Pronamide [3,5-dichloro-N-(1,1-dimethyl-2-propynyl)benzamide] was most phytotoxic to oat (Avena sativa L.) when placed in the seed zone and to quackgrass (Agropyron repens (L.) Beauv.), when placed in the rhizome zone. Inhibition of part of the buds by pronamide on detached quackgrass rhizome sections did not influence other buds. Foliar applications of pronamide were not phytotoxic to established oat or quackgrass. Foliar-applied 14C-pronamide showed little uptake by quackgrass. Application to the roots of established plants showed rapid root uptake and movement to the foliage. 14C-pronamide was rapidly absorbed by oat seedlings for the first 0.5 hr and subsequently at a much slower rate. Over 60% of the pronamide taken up after 1 hr was exchangeable. Pronamide was adsorbed to the cell walls of treated roots, but little was associated with nuclear, mitochondrial, microsomal, or soluble protein fractions. Pronamide was adsorbed to varying degrees depending on soil type. Adsorption was more highly correlated with soil organic matter content than with cation exchange capacity, clay content, or pH.

Site-specific weed management recommendations require knowledge of weed species, density, and location in the field. This study compared several sampling techniques to estimate weed density and distribution in two 65-ha no-till Zea mays–Glycine max rotation fields in eastern South Dakota. The most common weeds (Setaria viridis, Setaria glauca, Cirsium arvense, Ambrosia artemisiifolia, and Polygonum pensylvanicum) were counted by species in 0.1-m2 areas on a 15- by 30-m (1,352 points in each field) or 30- by 30-m (676 points in each field) grid pattern, and points were georeferenced and data spatially analyzed. Using different sampling approaches, weed populations were estimated by resampling the original data set. The average density for each technique was calculated and compared with the average field density calculated from the all-point data. All weeds had skewed population distributions with more than 60% of sampling points lacking the specific weed, but very high densities (i.e., > 100 plants m−2) were also observed. More than 300 random samples were required to estimate densities within 20% of the all-point means about 60% of the time. Sampling requirement increased as average density decreased. The W pattern produced average species densities that often were similar to the field averages, but information on patch location was absent. Weed counts taken on the 15- by 30-m grid were dependent spatially and weed contour maps were developed. Kriged maps presented both density and location of weed patches and could be used to establish management zones. However, grid-sampling production fields on a small enough scale to obtain spatially dependent data may have limited usefulness because of time, cost, and labor constraints.

The phytotoxicity of 3-[p-(p-chlorophenoxy)phenyl]-1,1-dimethylurea (chloroxuron) usually decreased as the stage of growth of five weed species at treatment increased. Giant foxtail (Setaria faberii Herrm.), velvetleaf (Abutilon theophrasti Medic.), and the cotyledonary stage of cocklebur (Xanthium pensylvanicum Wallr.) were most resistant to the herbicide. Ivyleaf morningglory (Ipomoea hederacea (L.) Jacq.) and jimsonweed (Datura stramonium L.) were more susceptible to chloroxuron. Soybean (Glycine max (L.) Merr.) seemed less susceptible at the cotyledonary stage than at later stages. Phytotoxicity on both weeds and soybeans was increased by increased temperature and relative humidity following chloroxuron application. The phytotoxicity of chloroxuron also was increased by simulated rainfall in greenhouse studies.

Experimental objectives were to assess metribuzin tolerance of predominately privately developed soybean cultivars and to evaluate a greenhouse screening procedure. In field results in 1982, ‘Vinton 81’, ‘Northrup King 1884’ and ‘L77-1863’ soybean cultivars were extremely sensitive to metribuzin at 0.56 kg/ha, averaging 34% injury. The other 45 cultivars showed no significant injury at the 0.56 kg/ha rate, from 9 to 46% injury at 1.4 kg/ha, and 18 to 72% injury at 2.2 kg/ha. In greenhouse hydroponic studies, these same three soybean cultivars were killed, while the other 45 cultivars were injured from 15 to 82%. A good agreement of greenhouse and field data was determined, with a correlation coefficient of r = 0.82.

There is increasing interest among developmental psychopathologists in broad transdiagnostic factors that give rise to a wide array of clinical presentations (multifinality), but little is known about how these processes lead to particular psychopathological manifestations over the course of development. We examined whether individual differences in the error-related negativity (ΔERN), a neural indicator of error monitoring, predicts whether early persistent irritability, a prototypical transdiagnostic construct, is associated with later internalizing versus externalizing outcomes. When children were 3 years old, mothers were interviewed about children's persistent irritability and completed questionnaires about their children's psychopathology. Three years later, EEG was recorded while children performed a go/no-go task to measure the ΔERN. When children were approximately 9 years old, mothers again completed questionnaires about their children's psychopathology. The results indicated that among children who were persistently irritable at age 3, an enhanced or more negative ΔERN at age 6 predicted the development of internalizing symptoms at age 9, whereas a blunted or smaller ΔERN at age 6 predicted the development of externalizing symptoms. Our results suggest that variation in error monitoring predicts, and may even shape, the expression of persistent irritability and differentiates developmental trajectories from preschool persistent irritability to internalizing versus externalizing outcomes in middle to late childhood.

The central serotonergic system has been implicated in the pathophysiology of panic disorder (PD) by evidence of abnormally elevated serotonin-turnover, reduced pre- and post-synaptic 5-HT1A−receptor sensitivity and binding and clinical improvement during administration of agents that enhance serotonergic transmission. Polymorphisms in genes that putatively influence serotonergic neurotransmission increase the vulnerability for developing PD specifically in males. We tested the hypotheses that serotonin transporter (5-HTT) binding is elevated in PD subjects vs. healthy controls in regions where in vivo evidence exists for both elevated 5-HTT and 5-HT1A receptor levels in PD and investigated whether the extent of this difference depends upon gender. Volunteers were out-patients with current PD (n=24) and healthy controls (n=24). The non-displaceable component of 5-HTT binding-potential (BPND) was measured using positron emission tomography and the 5-HTT selective radioligand, [11C]DASB. PD severity was assessed using the PD Severity Scale. The 5-HTT-BPND was increased in males with PD relative to male controls in the anterior cingulate cortex (F=8.96, pFDR=0.01) and midbrain (F=5.09, pFDR=0.03). In contrast, BPND did not differ between females with PD and female controls in any region examined. The finding that 5-HTT-binding is elevated in males but not in females with PD converges with other evidence suggesting that dysfunction within the central serotonergic system exists in PD, and also indicates that such abnormalities are influenced by gender. These findings conceivably may reflect a sexual dimorphism that underlies the greater efficacy of serotonin reuptake inhibitor treatment in females vs. males with PD.

This study examined whether participation in a variety of lifestyle activities was comparable to frequent participation in cognitively challenging activities in mitigating impairments in cognitive abilities susceptible to aging in healthy, community-dwelling older women. Frequencies of participation in various lifestyle activities on the Lifestyle Activities Questionnaire (LAQ) were divided according to high (e.g., reading), moderate (e.g., discussing politics), and low (e.g., watching television) cognitive demand. We also considered the utility of participation in a variety of lifestyle activities regardless of cognitive challenge. Immediate and delayed verbal recall, psychomotor speed, and executive function were each measured at baseline and at five successive exams, spanning a 9.5-year interval. Greater variety of participation in activities, regardless of cognitive challenge, was associated with an 8 to 11% reduction in the risk of impairment in verbal memory and global cognitive outcomes. Participation in a variety of lifestyle activities was more predictive than frequency or level of cognitive challenge for significant reductions in risk of incident impairment on measures sensitive to cognitive aging and risk for dementia. Our findings offer new perspectives in promoting a diverse repertoire of activities to mitigate age-related cognitive declines. (JINS, 2012, 18, 286–294)

According to the free radical theory, aging is caused by the damaging effects of oxygen radicals. These agents are produced continuously and they become toxic when their intra-cellular levels become elevated. Although well-known for the damage they cause, recent studies indicate that free radicals may also have a beneficial side regulating some of the processes within a cell. With aging, however, it seems that the ability to control endogenous concentrations declines, and rising levels become progressively more harmful. In addition to the primary changes, the effects of free radical damage should also be examined at the secondary level. Because of its importance in regulating homeostatic mechanisms, it is possible that in this regard the hypothalamus may play a crucial role in the aging process. Progressive loss of function in this centre may lead to systemic changes which cause widespread disruption throughout the organism.