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Predictive analytics in health is a complex, transdisciplinary field requiring collaboration across diverse scientific and stakeholder groups. Pilot implementation of participatory research to foster team science in predictive analytics through a partnered-symposium and funding competition. In total, 85 stakeholders were engaged across diverse translational domains, with a significant increase in perceived importance of early inclusion of patients and communities in research. Participatory research approaches may be an effective model for engaging broad stakeholders in predictive analytics.
Recent data suggest that a disturbance in the development of joint attention skills is a specific characteristic of young autistic children. This observation may have both theoretical and clinical significance. However, many pertinent issues remain to be addressed with regard to the parameters of joint attention disturbance in children with autism. This study attempted to address several of these issues. The study examines the effects of mental age and IQ on the joint attention skills of children with autism, mental retardation, and normal development. The study also examined the relation of joint attention behaviors to the parent's report of symptoms presented by children with autism. The results suggested that, differences in IQ and mental age may be related to differences in the type of joint attention skill deficits displayed by children with autism. The results also suggested that joint attention disturbance is associated with a circumscribed, but social cluster of symptoms observed among young autistic children by their parents. The implications of these findings for developmental models of autism are discussed.
Children exposed to alcohol prenatally have been found to be at risk for developmental and behavioral problems; however, the relation between maternal alcohol consumption and other environmental factors has not been fully explored in the literature. In this study, subjects were 44 firstborn infants of women over 30 years of age. Structural equation modeling was used to test the hypothesis that maternal alcohol use during pregnancy was related to infant negative affect. Furthermore, negative affect was assumed to influence the mother-infant relationship. It was hypothesized that mothers of infants exhibiting negative affect would be less positive in interaction and that insecure infant attachment behavior would be more prevalent in these infants. Results of model testing confirmed the hypothesis. In addition, maternal alcohol consumption following pregnancy was not found to influence significantly either maternal interaction or infant attachment behavior.
This study involved observations of children's behaviors in interactive situations with both familiar and unfamiliar partners. The greatest differences between the autistic and nonautistic children were in an unstructured situation where caregivers did not initiate interactions. In this situation, autistic children rarely looked to the partner or initiated social bids to the partner. They also were less focused on the toys available for play compared to nonautistic children. However, the autistic children were similar in their interactive responses to the partner in an adult-initiated social situation. Individual differences confirmed that more able autistic children in terms of cognitive and language abilities also engaged in greater social and communicative behavior with the partner. These findings suggest that the ways in which social deficits are manifested by autistic children are variable with respect to the context in which they are measured.
The formulation or recognition of contrasting models is an essential process in any scientific enterprise. Just as the juxtaposition of color and line may intensify the perception of elements in a painting, so the contrast of models in science brings the fundamental principles and questions of a field of inquiry into clearer focus. Within the field of mental retardation the debate over the developmental and difference models has exemplified this process (Baumeister, 1987).
Two fundamental questions are commonly associated with this debate. The first concerns the etiology of mental retardation. Advocates of difference theories of mental retardation often maintain that mental retardation is the result of a distinct organic disturbance that leads to deficits in intellectual development. For example, Ellis and Cavalier (1982) have argued that mental retardation is presumptive evidence of organic pathology.
Alternatively, the developmental model suggests that there are two groups of mentally retarded individuals – one resulting from a distinct disturbance of physiology (e.g., Down syndrome or hydrocephaly), the other with an unknown etiology. It is assumed that for a significant number of individuals in this latter group, mental retardation results not from a distinct disturbance of organic process, but rather from natural, genetic variation in processes associated with intellectual development (Zigler, 1967; Zigler, 1982; Zigler & Hodapp, 1986).
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