This paper reviews 70 years of cricket ball swing literature and reassesses the results in light of new measurements. A comparison of ball tracking data with published experimental results shows that current understanding does not explain the behaviour observed in professional cricket matches. Descriptions of cricket ball boundary layer aerodynamics are updated with new results which show that the seam acts more like a series of vortex generators than a trip and that there is a laminar separation bubble on the seam side of the ball. Previous results for reverse swing are consolidated and compared with new data, showing that different magnitudes of swing occur depending on the condition of both sides of the ball. Variation in pressure and temperature should be included when the Reynolds number, a non-dimensional ball speed, is calculated, while humidity can be neglected. Studies on the effect of wind speed and direction are summarised and results considering the effect of free-stream turbulence are compared with new measurements. Throughout the paper, recommendations for future work are suggested. These include quantitative study of the effect of surface defects and roughness, an assessment of whether atmospheric turbulence can affect swing and investigation into the effect of backspin on swing.

In ad 872–3 a large Viking Army overwintered at Torksey, on the River Trent in Lincolnshire. We have previously published the archaeological evidence for its camp, but in this paper we explore what happened after the Army moved on. We integrate the findings of previous excavations with the outcomes of our fieldwork, including magnetometer and metal-detector surveys, fieldwalking and targeted excavation of a kiln and cemetery enclosure ditch. We provide new evidence for the growth of the important Anglo-Saxon town at Torksey and the development of its pottery industry, and report on the discovery of the first glazed Torksey ware, in an area which has a higher density of Late Saxon kilns than anywhere else in England. Our study of the pottery industry indicates its continental antecedents, while stable isotope analysis of human remains from the associated cemetery indicates that it included non-locals, and we demonstrate artefactual links between the nascent town and the Vikings in the winter camp. We conclude that the Viking Great Army was a catalyst for urban and industrial development in Torksey and suggest the need to reconsider our models for Late Saxon urbanism.

Multiple sclerosis is the leading non-traumatic cause of disability in young adults, affecting up to 100,000 Canadians. This chronic inflammatory and neurodegenerative disease of the central nervous system leads to irreversible neurologic disability if inadequately controlled. Though many current medications are available that reduce inflammatory damage, most patients continue to show some evidence of disease activity and accrue disability. In this review, we discuss the role of immune ablation followed by autologous hematopoietic stem cell transplantation (AHSCT), a therapeutic option for select patients with a more aggressive disease course. By “resetting” the immune system with a variety of ablative conditioning regimens, followed by immune reconstitution, this therapy has shown a durable response in halting evidence of inflammatory activity in most patients, without the need for continued disease-modifying therapies (DMT). Since the introduction of this therapy, there have been advances in patient selection and supportive care, such that morbidity has significantly declined and treatment-related mortality is minimized. Recent phase-II trials have shown excellent results in efficacy and safety of AHSCT; however, challenges exist which require ongoing study. The future challenges include comparing the variety of AHSCT conditioning regimens with each other as well as with existing highly effective DMT; identifying patients with an aggressive disease course through novel biomarkers who may benefit the most from AHSCT; and surveillance of long-term outcomes of different treatment protocols. In select patients, replacing the immune system with AHSCT holds promise of fundamentally altering the trajectory of their aggressive disease course.

Background: There is an unmet need for blood-based biomarkers that can reliably detect MS disease activity. Serum Biomarkers of interest includ Neurofilament-light-chain (NfL), Glial-fibrillary-strocyte-protein(GFAP) and Tau. Bone Marrow Transplantation (BMT) is reserved for aggressive forms of MS and has been shown to halt detectable CNS inflammatory activity for prolonged periods. Significant pre-treatment tissue damage at followed by inflammatory disease abeyance should be reflected longitudinal sera collected from these patients. Methods: Sera were collected from 23 MS patients pre-treatment, and following BMT at 3, 6, 9 and 12-months in addition from 33 non-inflammatory neurological controls. Biomarker quantification was performed with SiMoA. Results: Pre-AHSCT levels of serum NfL and GFAP but not Tau were elevated compared to controls (p=0.0001), and NfL correlated with lesion-based disease activity (6-month-relapse, MRI-T2 and Gadolinium-enhancement). 3-months post-treatment, while NfL levels remained elevated, Tau/GFAP paradoxically increased (p=0.0023/0.0017). These increases at 3m correlated with MRI ‘pseudoatrophy’ at 6-months. NfL/Tau levels dropped to that of controls by 6-months (p=0.0036/0.0159). GFAP levels dropped progressively after 6-months although even at 12-months remained higher than controls (p=0.004). Conclusions: NfL was the closest correlate of MS disease activity and treatment response. Chemotherapy-related toxicity may account for transient increases in NfL, Tau and MRI brain atrophy post-BMT.

Towards a comprehensive revision of Gesneriaceae in Sri Lanka, 12 names are here typified, of which 11 are lectotypifications, including one second-step lectotypification, and the other is a neotypification.

The new species Aeschynanthus scottii D.J.Middleton & H.J.Atkins from Vietnam is described.

Ion-exchanged montmorillonites behave as solid acid catalysts and are effective and selective catalysts for the hydration of ethylene. The reaction proceeds predominantly in the interlamellar environment of the clay catalyst. Ethylene conversions were found to be markedly dependent on the choice of exchangeable cation, with Al being the best of those examined.

Iraqite, a new mineral of the ekanite group from northern Iraq, has the composition (Ln1·33 Th0·66x0·15) (K1·07y0·93) (Ca3·49 Ln0·35 Na0·16) (Si15·69 Al0·27) (O39·93 F0·07) where x = U, Pb, Zr, Fe, Mg, and Cu, and y is presumed to be vacant sites. It occurs in granite in contact with dolomitic marble. The colour is pale greenish yellow; H 4½ Dcalc 3·28 and Dmeas 3·27 (Berman balance), both corrected for minor impurity and non-structural water. Optically it is uniaxially negative with ω 1·590 and ε 1·585 though some sections show anomalous extinction up to 7°. Space group is P4/mcc with a 7·61±0·01 and c 14·72±0·02 Å. Strongest lines of the indexed powder pattern are 5·28(100), 3·31(100), 2·64(100), 7·36(80), 3·38(80), 3·40(60), 2·7(40), 7·62(30). Thermal data are given.

Bohdanowiczite was first described in 1967 but incomplete data prevented its acceptance as a new mineral at that time. Additional data on the same material now characterize bohdanowiczite as a new species with the formula:

3[(Ag0.98Cu0.02)0.97(Bi0.97Pb0.03)1.02(Se0.83S0.17)2.01]

The mineral occurs in intimate intergrowths with clausthalite and wittichenite in polymetallic mineralization at Kletno in Poland. In reflected light bohdanowiczite has a creamy-yellow colour and short polysynthetic twinning is frequently observed. Cell parameters indexed on a hexagonal lattice are a = 4.183±0.008 Å and c = 19.561± 0.016 Å. Pm1 is the most likely space group. The strongest lines of the powder pattern are 2.91(100), 2.03(30), 3.40(20), 6.54(20), 2.09(18), 3.26(18). The calculated density is 7.72 gm/cm3 and the VHN between 63 and 96 kg/mm2.

Tristramite, a new mineral of the rhabdophane group, has the composition (Ca0.54U4+0.29Fe3+0.17)Σ1.00 [(PO4)0.79(SO4)0.12(CO3)0.07]Σ0.98·1.77H2O. It occurs as a late-stage replacement or matrix to brecciated uraninite (var. pitchblende) associated with sulphides in hydrothermal veins related to Hercynian granites in south-west England. It is hexagonal, space group P6222, with a 6.913 ± 0.003 Å and c 6.422 ± 0.006 Å. The strongest lines of the indexed powder pattern are 2.99 (100), 2.83 (100), 2.14 (50), 1.850 (50), 5.99 (40), 4.37 (40), 3.46 (30). For comparison, new indexed powder data for rhabdophane from Fowey Consols, Cornwall, are included. The mineral is pale yellow to greenish yellow, uniaxial positive with ω 1.644 and ε 1.664, and does not fluoresce in either short-or long-wave ultraviolet light. The habit is acicular or fibrous and no cleavage has been observed. Density (g/cm3) 3.8–4.2 (meas.), 4.18 (calc.).

Microprobe analyses of members of the erlichmanite-laurite series from Guma Water and Senduma, Sierra Leone and Tanah Laut, Borneo, indicate that complete solid solution is possible between OsS2 and RuS2 with considerable substitution of Os and Ru by Ir, Rh, and Pt. The cell size of the erlichmanite from Guma Water is a = 5.6183±0.0003 Å at a composition (Os0.61Ru0.30Ir0.06Rh0.03)Σ0.93S2 whilst the laurite from Senduma has a composition of (Ru0.88Os0.05Ir0.04 Rh0.03)Σ0.93S2 and a cell size of a = 5.6089±0.0005 Å. Substitution of Os for Ru provides the predominant cause of the variation of cell size. Substitution by other elements of the platinum group appears to produce little effect on cell size and is presumably controlled by genesis rather than considerations of crystal chemistry or structure. The recorded analyses for these elements indicate a pre-dominance of Ir over Rh for members of the series containing more than about 15% of the laurite molecule. For the remainder of the series Rh is more important than Ir. The reflectance in air and oil of the members of the series from Sierra Leone and Borneo are presented and the microhardness of the erlichmanite from Guma Water shown to be 1854 kg/mm2. This is the first report of laurite from Senduma, Sierra Leone.

A new mineral, nukundamite, from a Fijian kuroko deposit is described. It has been referred to as idaite, Cu5FeS6, or Cu5.5xFexS6.5x. Electron-probe analyses gave Cu 56.51, Fe 9.64, and S 33.51, total with traces of Ag and As is 99.79%. Hexagonal with a 3.782, c 11.187 Å, Z = 1. Empirical formula Cu3.37, Fe0.66, S3.97 on the basis of eight atoms. Copper-coloured, metallic lustre, cleavage {0001} perfect. Density (g cm−3) 4.53 (calc), 4.30 (meas). Strongly pleochroic from reddish orange (Ro) to pale grey (Re). Parallel extinction. Very strong anisotropy with pale green-grey rotation colours. Reflectance values and quantitative colour values in air and oil are given. Similarities with the covelline structure are indicated.

An attempt to fully describe idaite from the Ida mine was unsuccessful. The description of the type material therefore remains inadequate.

A mineral closely resembling eudialyte in single crystal X-ray pattern and chemistry has been found in one granite block from the 5 Mile Post area on Ascension Island. To our knowledge, eudialyte has not previously been recognized in this suite of granites although they contain two other rare zirconium silicates, dalyite and vlasovite. Textural evidence suggests that the eudialyte, which is remarkable for its high yttrium and REE content, crystallized from very late-stage magmatic fluids. Rare-earth patterns are only slightly fractionated (CeN/YN = 1.8–2.5) compared with those of allanites and sphenes from Skye granites which presumably have similar parageneses. In contrast, the whole-rock REE pattern shows greater enrichment of light REE (CeN/YN ∼ 10). This difference in REE pattern is considered to be due to the effects of REE and other element complexing related to the peralkalinity of the granite liquid.

Two new species of Oreocharis, O. tribracteata and O. rufescens, are described and a key to the species in Vietnam is provided. The new species have distinct features not previously, or rarely, observed in the genus, both showing the partial fusion of the calyx lobes into a tube, and the presence of three bracts in Oreocharis tribracteata.