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This chapter details the planning, logistics and execution of the eastern bettong (Bettongia gaimardi) translocation to Mulligans Flat Woodland Sanctuary (MFWS). The project aimed to restore ecosystem function by reintroducing this extinct mainland marsupial, known for its role as an ecosystem engineer. The translocation involved extensive inter-agency collaboration, ethical oversight and adaptive problem-solving. Key challenges included minimising stress-induced mortality, safeguarding pouch young and ensuring genetic diversity through strategic sourcing across Tasmania. Innovative trapping, sedation and transport protocols were developed, including custom crate designs and sedation trials using diazepam. A phased approach – pilot, trial and main translocation – allowed refinement of methods and risk mitigation. The project successfully relocated 89 individuals without adult mortality or pouch young loss. The chapter highlights the importance of interdisciplinary partnerships, adaptive management and rigorous planning in wildlife reintroductions, offering a model for future conservation translocations.
This chapter presents the reintroduction biology of the eastern bettong (Bettongia gaimardi) at Mulligans Flat Woodland Sanctuary (MFWS), detailing strategies, tactics, and outcomes across establishment, growth and regulation phases. Adaptive management guided translocation planning, health monitoring and post-release assessments. Immediate-release tactics proved more effective than delayed-release, with high survival and reproductive success. Physiological stress, body condition and genetic diversity were tracked, revealing improved health and stable population dynamics. The population reached density dependence within six years, indicating successful regulation. Genetic monitoring confirmed retention of source diversity and highlighted the need for long-term sampling. A trial reintroduction beyond predator-proof fencing tested coexistence with invasive predators, introducing the ‘Goldilocks Zone’ concept for adaptive predator exposure. The chapter proposes ‘coexistence conservation’ as a long-term strategy to restore native species in landscapes where eradication of invasive predators is unfeasible, emphasising evolutionary adaptation and multi-stage trials.
The successful reintroduction of eastern bettongs relies on suitable food being available, particularly truffles (underground fungal fruitbodies). Here, we compared stable isotopes (carbon (δ13C) and nitrogen (δ15N)) and radiocarbon (∆14C) in hair and scat in bettongs subsequently reintroduced to Mulligan Flat Woodland Sanctuary (MFWS) against marsupial species of different diets to test whether such measurements are useful for dietary assessments. Patterns in bettong scat δ13C reflected seasonal shifts in the consumption of photosynthate derived from C3 plants (dicots and temperate grasses) versus C4 plants (tropical grasses), whereas a winter peak in scat δ15N reflected maximum reliance on truffle consumption. In hair, eastern bettongs resembled preferential fungivores in δ13C and δ15N and differed from carnivores, grazers, herbivores and opportunistic fungivores. Radiocarbon levels were higher in fungivorous potoroos than in wallaby grazers, suggesting similar measurements in eastern bettongs could assess fungal importance in their diet. These isotopic measurements will be useful for assessing the diets of reintroduced bettongs and other fungivorous marsupials in new environments.
Crystalline ice plant [Cryophytum crystallinum (L.) N.E. Br.] is a succulent plant indigenous to South Africa. It is a highly invasive weed in North America. There are currently three weevil species from the native range that show promise as potential biological control agents for invasive populations in North America. The present study used a ddRADseq (double digest restriction site–associated DNA sequencing) population genetic technique to match the invasive populations in North America to their source of origin to prioritize survey areas where the best-matched agent genotypes are likely to occur. We found that populations in the Canary Islands and Morocco closely matched those in the invaded North American range and that this genetic cluster was most similar to the South African native range sites surrounding the Cape Town area and those from Aniston Village farther east along the coastline. There was evidence of an invasion route from South Africa to the Mediterranean Basin, with a secondary bridgehead invasion that likely took place from there to North America. Genetic structuring within the native range revealed a total of four distinct populations, where sites north and south of Cape Town were unique and did not match the invasive populations. We found a unique outlier population in the Northern Cape that displayed intermediate morphological traits between C. crystallinum and its close relative, ice plant (Mesembryanthemum guerichianum Pax; syn.: Cryophytum guerichianum Pax). Surveys for biological control agents should focus on the areas between Kalk Bay and Yzerfontein in the Western Cape and sites surrounding Arniston Village.
Children with CHD require ICU admissions, putting them at risk for Post-intensive Care Syndrome in Paediatrics defined as physical, cognitive, social, and emotional health impairments following ICU discharge. There are few studies assessing Post-intensive Care Syndrome in Paediatrics in the CHD population. This study assessed the presence of Post-intensive Care Syndrome in Paediatrics in the CHD community and its relationship with health-related quality of life.
Methods:
CHD patients 5–18 years having 1 or more cardiac ICU admissions were evaluated in the Newborn ICU-Cardiac Neurodevelopmental Program from 9/2017 to 9/2020. Physical, cognitive, social, and emotional questionnaires measured each domain. Patients were considered impaired if 2 or more domain questionnaires were abnormal. If any domain showed impairment, Post-intensive Care Syndrome in Paediatrics was present. Predictors included demographic, disease severity, and ICU variables. Health-related quality of life was measured using the Paediatric Cardiac Quality of Life Inventory. Models were created using logistic and linear regression.
Results:
Of the 117 CHD patients, 50% were male having a mean age of 8.4 and a 5 year median time since last ICU admission. Post-Intensive Care syndrome in Pediatrics was found in 80% of the cohort: 36% physical, 70% cognitive, 26% social, and 33% emotional impairment. Patients with a longer time since last ICU admission showed less physical and emotional impairment (p < 0.05) with emotional impairment associated with worse health-related quality of life (p < 0.001).
Conclusions:
Post-intensive Care Syndrome in Paediatrics was present in most CHD patients. Worse emotional health was associated with lower health-related quality of life.
Why are some constitutions amended more frequently than others? Studies of amendment rates have been plentiful but have not generated much theoretical or empirical consensus because the extant literature rests rest on a strong and unwarranted assumption that social capacity to navigate amendment rules is constant across space and time. By contrast, the authors of this Element argue that this social capacity varies by civic connectedness. Drawing upon previous studies that find social capital mitigates transaction costs, this Element outlines the myriad ways in which social capital helps elites, social movements, and ordinary citizens solve the collective action problems associated with constitutional reform. The authors find evidence for their theory using a variety of measures, methods, and units of analysis.
We describe the latest iteration of upgrades (designated Phase III) to the Murchison Widefield Array (MWA), in the fourth paper in a series that covers the evolution of the telescope from design concept to initial operational facility, and through two major upgrades. As part of the Phase III upgrade of the MWA, we report the completion of work to design, build, and deploy a new fleet of digital receivers that further optimise the MWA for Epoch of Reionisation observations. These receivers complement existing receivers, such that the MWA now supports the full correlation of all 256 antenna tiles currently in the array. This step releases the MWA from the prior constraint of having to correlate only 128 of the 256 tiles at any given time, which means that the maximum instantaneous sensitivity of the MWA is doubled and the maximum number of interferometric baselines is approximately quadrupled. The upgrade is fundamentally enabled by the new MWAX correlator and various other improvements to the MWA sub-systems. In this paper we describe the new digital receivers and the other improvements that result in the Phase III system. A range of operational benefits arise from the upgrade and scientific flexibility is increased. We also comment on the transition from the MWA to the SKA-Low facility near the end of the decade, including a description of some unique science opportunities utilising joint MWA/SKA-Low data during the Science Verification phase of the SKA-Low Array Assembly 2 (AA2) period.
After the French Revolution led eventually to a Napoleonic invasion of Spain, the feckless King Carlos IV, Queen María Luisa, and their son Fernando decamped for France in 1808. Without a functioning government, the Spanish people and a rag-tag army harassed the French but won few battles before England sent seasoned troops that finally ousted the French. Fernando VII returned amid revolutions in the Americas that shattered Spanish America into dozens of independent republics. The king also had to accept a constitution that limited his power. His daughter, Isabel II, never understood her role as a constitutional monarch, and a series of military coups and changes in government eventually led to her ouster and a brief republican government. A Bourbon restoration failed to help heal the fissures in Spanish political life, in which compromise was rare and various factions alternated in power through a cynical and corrupt system of managed elections. Amid increasing violence and unrest, Alfonso XIII accepted a military dictator to run the government. When he fell from favor, and the army disgraced itself during a war in Morocco, the king went into exile in 1931, allowing politicians on the left to declare a republic.
The varied topography and climate of Iberia posed challenges for prehistoric hominids, as well as for later traders, fishers, farmers, and herders attracted by the peninsula’s mineral wealth, arable land, and diversity of marine and land animals. Iberians arrived from North Africa, Celts later arrived from the north, and Phoenicians and Greeks arrived from the Mediterranean. All of these diverse peoples brought their culture and language to Spain – founding cities, farming the land, mining, herding, trading, and therefore connecting what the Greeks called Iberia to the Mediterranean, North Africa, and Northern Europe.
When municipal elections favored republican candidates in 1931, King Alfonso XIII went into exile, and politicians declared a republic, polarizing Spanish society further. Republican programs included ambitious social, economic, and cultural initiatives to improve lives, but the government was faction-ridden from the start. Increasing street violence and several revolts persuaded a cadre of army officers to launch a coup in April 1936 that became a civil war when the government refused to yield. The Spanish Civil War, marked by atrocities on both sides, pitted right-wing Nationalists, led by General Francisco Franco, against an increasingly left-wing Republic. It ended after hundreds of thousands of deaths with Franco in power, tens of thousands of Spaniards in exile, and Spain isolated during the Second World War, supposedly neutral but sending troops to fight Soviet Russia in support of Nazi Germany. The postwar period brought misery, widespread hunger, and continued isolation that was only eased during the anti-Soviet Cold War of the 1950s. The following decade brought an economic boom and the relaxation of certain aspects of the dictatorship. By the time of Franco’s death in 1975, Spaniards were poised to enter a new epoch but wary about what it might bring.
Diets low in diverse fibre-rich plant foods contribute to the rise of chronic disease. The BIOME study (NCT06231706; 6-week parallel randomised controlled trial) in 399 adults (35–65 years; BMI 18·5–40 kg/m2; fibre intake < 20 g/d) investigated a whole-food plant blend containing > 30 ingredients, rich in (poly)phenols, fibre and micronutrients. Participants were randomised (1:1:1) to the blend (30 g/d), an isoenergetic control (bread croutons, 28 g/d) or probiotic (Lactobacillus rhamnosus, 15bn CFU/d). Analysts were blinded to allocation. The primary outcome was change in ‘favourable’ and ‘unfavourable’ gut microbiome species (ZOE Microbiome Health Ranking 2025); secondary outcomes included blood metabolites, symptoms, stool output, anthropometry, hunger, sleep, energy and mood. A crossover sub-study explored postprandial glucose, hunger and mood. Of 349 participants analysed (fifty excluded), self-reported adherence was > 98 %. The 30+ plant blend resulted in more species changing relative abundance at 6 weeks v. control (57 v. 14 species-level genome bins (SGB), P < 0·001) and probiotic (57 v. 4 SGB, P < 0·001). There were no significant between-group differences in microbiome health ranks of significantly changing species (increasing or decreasing). Blend participants self-reported reduced indigestion, constipation, heartburn and flatulence and increased energy v. control (all P < 0·05). Six related but no serious adverse events occurred. In the sub-study, adding the blend to a high-carbohydrate meal (v. meal alone) reduced hunger, increased fullness and energy (3-h incremental AUC, all P < 0·05), with no effect on postprandial glucose. This 30+ plant blend represents a simple strategy to modify gut microbiome composition and benefit gastrointestinal symptoms in healthy adults.
Under Muslim rule of what they called al-Andalus, the caliphate of Córdoba became one of the premier centers of the Islamic world. Islam tolerated other People of the Book, as they called Christians and Jews, but with restrictions. Over the eight centuries in which Muslim forces held sway in Iberia, the various cultures and languages of the peninsula developed and blended to a certain extent, which came to be called convivencia (lit., living together). Nonetheless, Christian forces began a reconquest of the land from the Muslims, beginning in the north and moving in stages toward the south. They benefited from the fragmentation of rule in the Muslim areas and the frequent disruptions caused by successive invasions from North Africa. As Christian forces captured territory, they formed various kingdoms in Portugal, Castile-León, and Aragón. Loyal supporters received grants of land from grateful monarchs and thus became a landed aristocracy. By the end of the thirteenth century, what would be known as the Christian Reconquest was virtually complete.
Castile and Aragón stayed amalgamated under the Spanish Habsburg dynasty, which reigned for two centuries. Early on, Spaniards conquered the Aztec and Inca empires in the Americas, and huge transatlantic merchant fleets connected Spain with its growing American Empire. After unprecedented silver deposits were discovered in both North and South America, Spanish silver and other treasure contributed to growth and inflation around the globe. The long-sought return route eastward from Asia to the Americas allowed transpacific trade to begin in 1565, while conquest of the Philippines made Spain’s composite monarchy, as it is often called, truly global. Spanish power declined in the late seventeenth century, the victim of overextension and continual warfare. When the Habsburgs died out in 1700, a Bourbon prince had the best dynastic claim to become king of Spain. As Felipe V, he fought most of Europe to remain on the throne and would father three successive kings, whose reigns saw Spain’s global empire reach its greatest extent. Thereafter, the French Revolution and a Napoleonic invasion would shatter Spain and end the early modern period.
The major dynasties and rulers in each period are listed along with their dates, from medieval times through the eighteenth century. For the nineteenth, twentieth, and twenty-first centuries, monarchs, regents, dictators, and elected heads of government are listed along with their dates in power.
Roman armies entered Iberia at the end of the third century BCE and conquered the Carthaginians. Nonetheless, it required two centuries to bring what they called Hispania into the Roman orbit, due to the difficult terrain and the resistance of many local populations. Once established, the Romans brought considerable benefits to the inhabitants, including roads, bridges, aqueducts, the Latin language, law, and civic and cultural enhancements such as theaters, all of which left lasting traces into the present. They also converted to Christianity. As the Roman Empire faded in power, barbarians including the Visigoths invaded its borders. The Visigoths eventually arrived in Hispania and established their rule at the end of the sixth century, but they were overwhelmed by Muslim invaders from North Africa in the early seventh century. Nonetheless, although they left few traces of their own way of life, they preserved much of the Roman legacy.