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We measure the other-regarding behavior in samples from three related populations in the upper Midwest of the United States: college students, non-student adults from the community surrounding the college, and adult trainee truckers in a residential training program. The use of typical experimental economics recruitment procedures made the first two groups substantially self-selected. Because the context reduced the opportunity cost of participating dramatically, 91 % of the adult trainees solicited participated, leaving little scope for self-selection in this sample. We find no differences in the elicited other-regarding preferences between the self-selected adults and the adult trainees, suggesting that selection is unlikely to bias inferences about the prevalence of other-regarding preferences among non-student adult subjects. Our data also reject the more specific hypothesis that approval-seeking subjects are the ones most likely to select into experiments. Finally, we observe a large difference between self-selected college students and self-selected adults: the students appear considerably less pro-social.
When we open a random political science journal, we have a roughly two-to-one chance that the article is written by a man. Beyond this general finding, we know little about the gender gaps within political science knowledge production: Are women more represented in lower- or higher-ranked journals? Do they publish more single-authored or multiauthored papers? Do they publish more content in some fields than in others? This article answers these questions by analyzing an original dataset based on the International Political Science Abstracts (a peer-reviewed academic journal) from 2022 consisting of more than 7,000 articles and more than 13,000 authors in political science from around the world. We find no difference in the percentage of female authors between higher- and lower-ranked journals. We find a slightly higher propensity among women to publish in teams. Regarding subfields of study, women are particularly underrepresented in political theory, in which they publish only 21.6% of all published articles—which is an approximate 12-percentage-point deviation from the overall average.
This essay celebrates the BU Health Law Program upon its 70th anniversary, offering reflections on the founders of the program, Fran Miller, George Annas, and Wendy Mariner (“FGW,” endearingly), and their contributions to the field.
Current faculty offer reflections, including: Several speak to scholarly research, including Elizabeth McCuskey on health care finance, Aziza Ahmed on human rights, Dionne Lomax on antitrust, Christopher Robertson on trust, and Kathy Zeiler on the marketplace. Other contributors speak to the student experience, with Dianne McCarthy on mentorship, Laura Stephens on demanding excellence, Michael Ulrich on teaching, and Larry Vernaglia on merging law and public health. On FGW’s broader impacts, Nicole Huberfeld speaks to the translation of research to reach new audiences, and Kevin Outterson writes about FGW’s pivotal roles in establishing the health law field and the institutions that now define it.
Together these pieces testify to the astounding contributions of these scholar-teacher-leaders across many domains and dimensions of health law. While their contributions are countless and immeasurable, these reflections offer a start.
Discussions of George Berkeley often dismiss his Notebooks remarks that (1) bodies are powers that cause perceivers to have thoughts, and (2) bodies exist even when they are not perceived. I have previously noted these claims but have not explained how bodies are infinitely linked as thoughts (vs. ideas), and Melissa Frankel treats bodies as archetypes perceived individually by God but does not explain how they are individuated. I argue that because bodies identify objects only for finite minds, they are derivative powers by which individuated objects are related to one another infinitely.
The use of face masks has been widely promoted and at times mandated to prevent coronavirus disease 2019 (COVID-19). The 2023 publication of an updated Cochrane review on mask effectiveness for respiratory viruses as well as the unfolding epidemiology of COVID-19 underscore the need for an unbiased assessment of the current scientific evidence. It appears that the widespread promotion, adoption, and mandating of masking for COVID-19 were based not primarily on the strength of evidence for effectiveness but more on the imperative of decision-makers to act in the face of a novel public health emergency, with seemingly few good alternatives. Randomized clinical trials of masking for prevention of COVID-19 and other respiratory viruses have so far shown no evidence of benefit (with the possible exception of continuous use of N95 respirators by hospital workers). Observational studies provide lower-quality evidence and do not convincingly demonstrate benefit from masking or mask mandates. Unless robust new evidence emerges showing the effectiveness of masks in reducing infection or transmission risks in either trials or real-world conditions, mandates are not warranted for future epidemics of respiratory viral infections.
A high-charge smectite from Arizona [cation-exchange capacity (CEC) = 120 meq/100 g] and a low-charge smectite from Wyoming (CEC = 90 meq/100 g) were used to prepare homoionic tetra-methylammonium (TMA)-clay complexes. The adsorption of benzene, toluene, and o-xylene as vapors by the dry TMA-clays and as solutes from water by the wet TMA-clays was studied. The adsorption of the organic vapors by the dry TMA-smectite samples was strong and apparently consisted of interactions with both the aluminosilicate mineral surfaces and the TMA exchange ions in the interlayers. In the adsorption of organic vapors, the closer packing of TMA ions in the dry high-charge TMA-smectite, compared with the dry low-charge TMA-smectite, resulted in a somewhat higher degree of shape-selective adsorption of benzene, toluene, and xylene. In the presence of water, the adsorption capacities of both samples for the aromatic compounds were significantly reduced, although the uptake of benzene from water by the low-charge TMA-smectite was still substantial. This lower sorption capacity was accompanied by increased shape-selectivity for the aromatic compounds. The reduction in uptake and increased selectivity was much more pronounced for the water-saturated, high-charge TMA-smectite than for the low-charge TMA-smectite. Hydration of the TMA exchange ions and/or the mineral surfaces apparently reduced the accessibility of the aromatic molecules to interlamellar regions. The resulting water-induced sieving effect was greater for the high-charge TMA-smectite due to the higher density of exchanged TMA-ions. The low-charge Wyoming TMA-smectite was a highly effective adsorbent for removing benzene from water and may be useful for purifying benzene-contaminated water.
OpenAI is a research organization founded by, among others, Elon Musk, and supported by Microsoft. In November 2022, it released ChatGPT, an incredibly sophisticated chatbot, that is, a computer system with which humans can converse. The capability of this chatbot is astonishing: as well as conversing with human interlocutors, it can answer questions about history, explain almost anything you might think to ask it, and write poetry. This level of achievement has provoked interest in questions about whether a chatbot might have something similar to human intelligence and even whether one could be conscious. Given that the function of a chatbot is to process linguistic input and produce linguistic output, we consider that the most interesting question in this direction is whether a sophisticated chatbot might have inner speech. That is: might it talk to itself, internally? We explored this via a conversation with ‘Playground’, a chatbot which is very similar to ChatGPT but more flexible in certain respects. We put to it questions which, plausibly, can only be answered if one first produces some inner speech. Here, we present our findings and discuss their philosophical significance.
Evaluate the association between provider-ordered viral testing and antibiotic treatment practices among children discharged from an ED or hospitalized with an acute respiratory infection (ARI).
Design:
Active, prospective ARI surveillance study from November 2017 to February 2020.
Setting:
Pediatric hospital and emergency department in Nashville, Tennessee.
Participants:
Children 30 days to 17 years old seeking medical care for fever and/or respiratory symptoms.
Methods:
Antibiotics prescribed during the child’s ED visit or administered during hospitalization were categorized into (1) None administered; (2) Narrow-spectrum; and (3) Broad-spectrum. Setting-specific models were built using unconditional polytomous logistic regression with robust sandwich estimators to estimate the adjusted odds ratios and 95% confidence intervals between provider-ordered viral testing (ie, tested versus not tested) and viral test result (ie, positive test versus not tested and negative test versus not tested) and three-level antibiotic administration.
Results:
4,107 children were enrolled and tested, of which 2,616 (64%) were seen in the ED and 1,491 (36%) were hospitalized. In the ED, children who received a provider-ordered viral test had 25% decreased odds (aOR: 0.75; 95% CI: 0.54, 0.98) of receiving a narrow-spectrum antibiotic during their visit than those without testing. In the inpatient setting, children with a negative provider-ordered viral test had 57% increased odds (aOR: 1.57; 95% CI: 1.01, 2.44) of being administered a broad-spectrum antibiotic compared to children without testing.
Conclusions:
In our study, the impact of provider-ordered viral testing on antibiotic practices differed by setting. Additional studies evaluating the influence of viral testing on antibiotic stewardship and antibiotic prescribing practices are needed.
Despite the importance of assessing the quality with which low-intensity (LI) group psychoeducational interventions are delivered, no measure of treatment integrity (TI) has been developed.
Aims:
To develop a psychometrically robust TI measure for LI psychoeducational group interventions.
Method:
This study had two phases. Firstly, the group psychoeducation treatment integrity measure-expert rater (GPTIM-ER) and a detailed scoring manual were developed. This was piloted by n=5 expert raters rating the same LI group session; n=6 expert raters then assessed content validity. Secondly, 10 group psychoeducational sessions drawn from routine practice were then rated by n=8 expert raters using the GPTIM-ER; n=9 patients also rated the quality of the group sessions using a sister version (i.e. GPTIM-P) and clinical and service outcome data were drawn from the LI groups assessed.
Results:
The GPTIM-ER had excellent internal reliability, good test–retest reliability, but poor inter-rater reliability. The GPTIM-ER had excellent content validity, construct validity, formed a single factor scale and had reasonable predictive validity.
Conclusions:
The GPTIM-ER has promising, but not complete, psychometric properties. The low inter-rater reliability scores between expert raters are the main ongoing concern and so further development and testing is required in future well-constructed studies.
We introduce an original dataset of formal political participation for over 2,000 individuals included in the Forbes Billionaires List. We find that billionaire politicians are a surprisingly common phenomenon: Over 11% of the world’s billionaires have held or sought political office. Even compared to other elite groups known for producing politicians from their ranks, this is a high rate of political participation. Moreover, billionaires focus their political ambitions on influential positions, have a strong track record of winning elections, and lean to the right ideologically. We also document substantial cross-national variation: a country’s number of billionaire politicians is not simply a product of its total number of billionaires, but is instead related to regime type. Specifically, billionaires formally enter the political sphere at a much higher rate in autocracies than in democracies. We conclude by discussing the normative implications of our findings and outlining a new research agenda on billionaire politicians.
The U.S. Department of Agriculture–Agricultural Research Service (USDA-ARS) has been a leader in weed science research covering topics ranging from the development and use of integrated weed management (IWM) tactics to basic mechanistic studies, including biotic resistance of desirable plant communities and herbicide resistance. ARS weed scientists have worked in agricultural and natural ecosystems, including agronomic and horticultural crops, pastures, forests, wild lands, aquatic habitats, wetlands, and riparian areas. Through strong partnerships with academia, state agencies, private industry, and numerous federal programs, ARS weed scientists have made contributions to discoveries in the newest fields of robotics and genetics, as well as the traditional and fundamental subjects of weed–crop competition and physiology and integration of weed control tactics and practices. Weed science at ARS is often overshadowed by other research topics; thus, few are aware of the long history of ARS weed science and its important contributions. This review is the result of a symposium held at the Weed Science Society of America’s 62nd Annual Meeting in 2022 that included 10 separate presentations in a virtual Weed Science Webinar Series. The overarching themes of management tactics (IWM, biological control, and automation), basic mechanisms (competition, invasive plant genetics, and herbicide resistance), and ecosystem impacts (invasive plant spread, climate change, conservation, and restoration) represent core ARS weed science research that is dynamic and efficacious and has been a significant component of the agency’s national and international efforts. This review highlights current studies and future directions that exemplify the science and collaborative relationships both within and outside ARS. Given the constraints of weeds and invasive plants on all aspects of food, feed, and fiber systems, there is an acknowledged need to face new challenges, including agriculture and natural resources sustainability, economic resilience and reliability, and societal health and well-being.
Mass loss from the Amundsen Sea Embayment of the West Antarctic Ice Sheet is a major contributor to global sea-level rise (SLR) and has been increasing over recent decades. Predictions of future SLR are increasingly modelled using ensembles of simulations within which model parameters and external forcings are varied within credible ranges. Accurately reporting the uncertainty associated with these predictions is crucial in enabling effective planning for, and construction of defences against, rising sea levels. Calibrating model simulations against current observations of ice-sheet behaviour enables the uncertainty to be reduced. Here we calibrate an ensemble of BISICLES ice-sheet model simulations of ice loss from the Amundsen Sea Embayment using remotely sensed observations of surface elevation and ice speed. Each calibration type is shown to be capable of reducing the 90% credibility bounds of predicted contributions to SLR by 34 and 43% respectively.
Microscopy is a widely used method in biological research to observe the morphology and structure of cells. Amongst the plethora of microscopy techniques, fluorescent labeling with dyes or antibodies is the most popular method for revealing specific cellular organelles. However, fluorescent labeling also introduces new challenges to cellular observation, as it increases the workload, and the process may result in nonspecific labeling. Recent advances in deep visual learning have shown that there are systematic relationships between fluorescent and bright-field images, thus facilitating image translation between the two. In this article, we propose the cross-attention conditional generative adversarial network (XAcGAN) model. It employs state-of-the-art GANs (GANs) to solve the image translation task. The model uses supervised learning and combines attention-based networks to explore spatial information during translation. In addition, we demonstrate the successful application of XAcGAN to infer the health state of translated nuclei from bright-field microscopy images. The results show that our approach achieves excellent performance both in terms of image translation and nuclei state inference.
Dental healthcare personnel (DHCP) are at high risk of exposure to coronavirus disease 2019 (COVID-19). We sought to identify how DHCP changed their use of personal protective equipment (PPE) as a result of the COVID-19 pandemic, and to pilot an educational video designed to improve knowledge of proper PPE use.
Design:
The study comprised 2 sets of semistructured qualitative interviews.
Setting:
The study was conducted in 8 dental clinics in a Midwestern metropolitan area.
Participants:
In total, 70 DHCP participated in the first set of interviews; 63 DHCP participated in the second set of interviews.
Methods:
In September–November 2020 and March–October 2021, we conducted 2 sets of semistructured interviews: (1) PPE use in the dental community during COVID-19, and (2) feedback on the utility of an educational donning and doffing video.
Results:
Overall, 86% of DHCP reported having prior training. DHCP increased the use of PPE during COVID-19, specifically N95 respirators and face shields. DHCP reported real-world challenges to applying infection control methods, often resulting in PPE modification and reuse. DHCP reported double masking and sterilization methods to extend N95 respirator use. Additional challenges to PPE included shortages, comfort or discomfort, and compatibility with specialty dental equipment. DHCP found the educational video helpful and relevant to clinical practice. Fewer than half of DHCP reported exposure to a similar video.
Conclusions:
DHCP experienced significant challenges related to PPE access and routine use in dental clinics during the COVID-19 pandemic. An educational video improved awareness and uptake of appropriate PPE use among DHCP.
Tackling Scotland's drug-related deaths and improving outcomes from substance misuse treatments, including residential rehabilitation, is a national priority.
Aims
To analyse and report outcomes up to 4 years after attendance at a substance misuse residential rehabilitation programme (Lothians and Edinburgh Abstinence Programme).
Method
In total, 145 participants were recruited to this longitudinal quantitative cohort study of an abstinence-based residential rehabilitation programme based on the therapeutic community model; 87 of these participants were followed up at 4 years. Outcomes are reported for seven subsections of the Addiction Severity Index-X (ASI-X), together with frequency of alcohol use, heroin use, injecting drug use and rates of abstinence from substances of misuse.
Results
Significant improvement in most outcomes at 4 years compared with admission scores were found. Completing the programme was associated with greater rates of abstinence, reduced alcohol use and improvements in alcohol status score (Mann–Whitney U = 626, P = 0.013), work satisfaction score (U = 596, P = 0.016) and psychiatric status score (U = 562, P = 0.007) on the ASI-X, in comparison with non-completion. Abstinence rates improved from 12% at baseline to 48% at 4 years, with the rate for those completing the programme increasing from 14.5% to 60.7% (χ2(2, 87) = 9.738, P = 0.002). Remaining abstinent from substances at follow-up was associated with better outcomes in the medical (U = 540, P < 0.001), psychiatric (U = 273.5, P < 0.001) and alcohol (U = 322.5, P < 0.001) subsections of the ASI-X.
Conclusions
Attending this abstinence-based rehabilitation programme was associated with positive changes in psychological and social well-being and harm reduction from substance use at 4-year follow-up, with stability of change from years 1 to 4.
Black and Minority Ethnic (BME) communities have been disproportionately affected by COVID-19: death rates are higher and survival rates are lower, with statistics varying in different BME communities (Public Health England 2020b). BME communities are at risk of higher infection rates and mortality rates due to certain pre-disposed health conditions and living in poorer, overcrowded housing (Meer et al. 2020). These higher infection and mortality rates together with the fear of spreading the virus or catching it from others have caused further distress. Ethnic minorities in Britain have experienced a disproportional impact of COVID-19, as for these groups the pandemic was translated as a syndemic pandemic (Bambra et al. 2020) because of pre-pandemic inequalities on all social determinants of health such as unhealthy dietary practices, poor housing and working conditions, unemployment, poor access to healthcare, high levels of inactivity and discrimination that ethnic minorities and the majority of British Muslims live with.
This chapter highlights the disproportionate impact of COVID-19 on British Muslims and how the pandemic exposed prevalent health inequalities in the UK. We critically analyse the discussions around faith in relation to COVID-19, victim blaming, its impacts and the socioeconomic consequences of COVID-19 lockdowns on marginalised British Muslims. We evaluate the vulnerabilities of British Muslims working in the NHS and healthcare and the responses by professional Muslim organisations providing healthcare awareness. We explore the interplay of ethnicity, religion and deprivation in negotiating the particular challenges of living through COVID-19. We critically evaluate and problematise the notions around ‘vaccine hesitancy’, and question the emphasis on national religious organisations of British Muslims for responses to COVID-19 instead of professional medical organisations or small-scale community-based organisations. We assess the impact of COVID-19 on British Muslim families, children, charity and voluntary organisations, physical activity, mental health and wellbeing, and how British Muslims living in deprived neighbourhoods responded to the pandemic through engaging with community groups. We highlight the work of neighbourhood and community-based organisations and services for healthcare awareness by professional Muslim groups. This chapter also includes multidisciplinary perspectives of academics and practitioners on the pandemic, lockdown, vaccination and subsequent socioeconomic implications of COVID-19 with regard to British Muslims’ lived experience.
This chapter examines the deterioration of the woodblocks in several editions of Andreas Vesalius’ De humani corporis fabrica, the first fully illustrated anatomy atlas. Comparison of different woodcuts in the Fabrica reveals a consistent pattern of degradation across copies: perfect impressions of the woodblocks were selected to be bound to form a first-state book; impressions of the damaged woodblocks were bound together to form a later-state volume. This finding suggests the early modern print shop was not as disorganised as Adrian Johns and other historians have claimed in recent years.
Keywords: printing history, history of the book, history of anatomy, visual studies of science, Andreas Vesalius
Introduction
A plethora of scholarship from recent decades examines the complex processes whereby an early modern book came into existence. While printing obviously speeded up the production of books compared to the manuscript era, a print run of hundreds (let alone thousands) still required many months. During these months, printers could still fiddle with the format of the book, adding accidental and intended changes to text and images at the behest of correctors, authors, and typesetters. Sometimes, as the first sheets of a volume were being printed at full speed, the author was still finishing the text’s concluding section, writing up a fulsome epistle dedicatory, assembling the index, and composing an errata list of typographical errors. Arguably, the complexities of these processes made each exemplar of a printed book unique. They can give the impression that the production of books was a messy and unstable enterprise in the early modern world, and not the orderly business of standardized twentiethcentury production. Our chapter contributes to this historiographical debate by examining the temporal sequence of printing, asking whether exemplars produced at the beginning and end of the process differed from each other.
A well-established distinction between the different states of woodcuts, engravings, and etchings exists in the field of art history. The hundreds of sheets that printmakers pulled from the same copperplate or woodblock can often be grouped into separate and distinct states based either on the matrices’ deterioration, or on the artist’s intervention, as in the case of Rembrandt, who obsessively reworked his etchings throughout his career.
The Mapledurham estate in the far south of Oxfordshire is well known for its rich and varied collection of historic buildings. Preeminent amongst them is the Grade 1 listed Mapledurham House, the largest Jacobean manor house in the county, alongside which stands the surviving part of its medieval predecessor. Other nearby structures include the parish church and its estate-owned medieval aisle, a range of converted seventeenth-century almshouses, and a seventeenth- and eighteenth-century watermill. Outlying buildings include four medieval cruck-framed houses. The survival of these and other buildings and, in many cases, the lack of substantial alteration to them in recent centuries owes much to the longevity of the estate and the financial difficulties faced by its owners as Roman Catholic recusants. However, by the early twentieth century the future of the estate was uncertain and many of its buildings had fallen into decay. This article traces the contribution of John Joseph (‘Jack’) Eyston (1934–2019) to the continuation of the estate and in particular the restoration of many of its historic buildings. The opening of Mapledurham House to the public and changes in attitudes towards the preservation of historic building are discussed.
The 2,500-acre Mapledurham estate includes a large and varied set of historic buildings, the near forty listed structures representing probably the densest concentration in single ownership in the county. The estate's best-known architectural feature is Mapledurham House (Fig. 1, top left), a substantial brick-built mansion tree-ring dated to c.1608–12, which retains both its original H-plan and numerous internal details, including fine decorative plasterwork and woodwork. Georgian remodelling included re-fronting and the addition of a Gothick Roman Catholic chapel to the rear. Today the house is Grade 1 listed in recognition of its national importance. The Old Manor House, survivor of the medieval manorial complex on the same site, is of fifteenth-century and later date, its earliest element (Fig. 1, bottom left) being a two-storey structure with a three-bay lower chamber and two-bay upper hall, dendro-dated to 1448. The nearby parish church, heavily restored in 1863, incorporates a south aisle added as a chantry chapel for Sir Robert Bardolf (d. 1395), lord of Mapledurham Gurney manor (Fig. 1, bottom right). The aisle retains much of its original roof (repaired in 1471–2), together with some medieval floor tiles and glass.
Digital psychiatry could empower individuals to navigate their context-specific experiences outside healthcare visits. This editorial discusses how leveraging digital health technologies could dramatically transform how we conceptualise mental health and the mental health professional's day-day practice, and how patients could be enabled to navigate their mental health with greater agency.
This article reviews existing state laws related to autonomous vehicle (AV) safety, equity, and automobile insurance. Thirty states were identified with relevant legislation. Of these, most states had one or two relevant laws in place. Many of these laws were related to safety and insurance requirements. Data are needed to evaluate the effectiveness of these laws in order to guide further policy development.