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13 results

  • Section I - Perioperative Management

  • Edited by Dennis S. Chi, Memorial Sloan-Kettering Cancer Center, New York, Nisha Lakhi, Richmond University Medical Center, Staten Island, Nicoletta Colombo, University of Milan-Bicocca
  • Book:
    50 Big Debates in Gynecologic Oncology
    Published online:
    20 July 2023
    Print publication:
    03 August 2023, pp 1-10

  • Summary

    It is 2021 and conferences around the world still debate the pros and cons of mechanical bowel prep (MBP). It is baffling how a safe intervention used millions of times every day for screening colonoscopies is a subject of fierce discussions amongst colleagues, in book chapters, and lectures when applied to patients undergoing colorectal resection. Although we believe that for patients with advanced ovarian cancer undergoing cytoreductive surgery there are other quintessential questions to debate about, we understand that the debate over this issue is far from resolved and expert majority opinion has vacillated over the past decade. With all this in mind, as a disclaimer the authors are allowed to change their minds.

50 Big Debates in Gynecologic Oncology
  • Edited by Dennis S. Chi, Nisha Lakhi, Nicoletta Colombo
  • Published online:
    20 July 2023
    Print publication:
    03 August 2023
  • Highlighting over 50 hot topics where controversy exist in management of patients with gynecologic malignancy, this book presents expertly argued opinions for and against, incorporating current evidence and clinical trials outcomes. A diverse range of topics are included that pertain to several disciplines in gynecologic oncology, including surgical management of disease, medical oncology, immunotherapy, radiation therapy, as well as screening, preventive and palliative care. This book will be relevant to a diverse audience of practitioners and trainees including gynecologists, gynecological oncologists, surgeons, medical oncologists, radiation oncologists, and general medics. It will be a useful guide for practicing clinicians managing their patients, as well as a concise textbook for trainees and students preparing for examinations and board certifications in gynecologic oncology. Readers will gain an insight into topical controversies, critically evaluating the different sides to enhance their own clinical practice.

  • 9 - ‘Ultra-radical’ surgery in advanced ovarian cancer

  • from SECTION 3 - IMAGING AND THERAPY: STATE OF THE ART
  • Edited by Sean Kehoe, Richard J. Edmondson, Martin Gore, Iain A. McNeish
  • Book:
    Gynaecological Cancers
    Published online:
    05 February 2014
    Print publication:
    01 June 2011, pp 109-120

  • Summary

    Effective chemotherapy allows the performance of surgical cytoreduction to have improved outcomes. This chapter provides an outline for the rationale and implementation of a comprehensive cytoreductive surgical approach in advanced ovarian cancer. The most important prognostic factors refer primary surgical outcome and the response to postoperative chemotherapy. Multiple retrospective studies, pooled exploratory analyses and meta-analyses have demonstrated that the amount of residual disease after cytoreductive surgery inversely correlates with progression-free survival (PFS) and overall survival (OS). Disease involving the upper abdomen cephalad to the greater omentum (UAD) is frequently seen in women with ovarian cancer. Complications involving debulking of the left upper quadrant during cytoreduction have been evaluated. In centres where a comprehensive primary surgical approach can be offered, a primary cytoreductive approach should be the standard of care except for the high-risk group of women.