The development of the Neolithic way of life in the western Mediterranean during the sixth millennium cal. BC is the consequence of the spread of populations from the Near East after successive stages of cultural remodelling. Despite the clear contribution of the Near Eastern and Aegean Neolithic to the economic and technical changes that happened to the west, little is known here about their symbolic legacies, because of the scarcity of representations and ritual evidences associated to the earliest western Neolithic contexts. Excavations at the rock shelter of Pendimoun (southeastern France) yielded the first anthropomorphic stone sculpture from the western Mediterranean Neolithic (early sixth millennium cal. BC). Using both carving and painting techniques, it represents a realistic-looking human face and is a unique example within the western Mediterranean and European frameworks. After describing the shaping and colouring details of the mask, the authors here deal with its possible social significances and cultural connections.