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Adolescent girls and young women (AGYW) in sub-Saharan Africa are at high risk of HIV infection. HIV infection rates increase substantially among AGYW after the age of 18. In South Africa HIV prevalence rises from 6% among young women aged 15–19 years to 17% by ages 20–24. This age period marks a time of transition into adulthood and coincides with a number of key life events, such as finishing the mandatory years of schooling, leaving home, entering first sexual relationships and experiencing first pregnancies.(Human Sciences Research Council [HSRC], 2017) Key life events that include first pregnancy, coital debut, leaving school and parental death have all been found independently to be associated with an increased risk of HIV infection in young women. Young women who experience their first vaginal sex before the age of 15 are more likely to be living with HIV, and these early events are often characterized by forced sex and sex with older male partners who are more likely to be HIV infected (Pettifor et al, 2004, 2009; Wand and Ramjee, 2012). While school attendance has multiple developmental and later life benefits, leaving school increases the risk of HIV acquisition. Girls who do not attend school as often and who drop out are more likely to acquire HIV infection than those attending and who stay in school (Stoner et al, 2017) In one study, this association appears to be explained by school environments providing safer spaces where adolescent girls are more likely to have male partners closer in age and also have fewer sexual partners than those out of school (Stoner et al, 2018) Similar patterns have been observed for young women experiencing early adolescent pregnancy (before the age of 15), whereby HIV incidence is much higher, and those who experience adolescent pregnancy also have more risk factors for HIV infection such as older partners and more sexual partners (Christofides et al, 2014). Finally, loss of a parent has been found to be associated with HIV risk in young people; orphaned youth are more likely to be living with HIV and to report riskier sexual behaviour than non-orphaned youth (Operario et al, 2011).
This study describes findings from an assessment conducted to identify perceived knowledge gaps, information needs, and research priorities among state, territorial, and local public health preparedness directors and coordinators related to public health emergency preparedness and response (PHPR). The goal of the study was to gather information that would be useful for ensuring that future funding for research and evaluation targets areas most critical for advancing public health practice.
Methods
We implemented a mixed-methods approach to identify and prioritize PHPR research questions. A web survey was sent to all state, city, and territorial health agencies funded through the Public Health Emergency Preparedness (PHEP) Cooperative Agreement program and a sample of local health departments (LHDs). Three focus groups of state and local practitioners and subject matter experts from the Centers for Disease Control and Prevention (CDC) were subsequently conducted, followed by 3 meetings of an expert panel of PHPR practitioners and CDC experts to prioritize and refine the research questions.
Results
We identified a final list of 44 research questions that were deemed by study participants as priority topics where future research can inform PHPR programs and practice. We identified differences in perceived research priorities between PHEP awardees and LHD survey respondents; the number of research questions rated as important was greater among LHDs than among PHEP awardees (75%, n=33, compared to 24%, n=15).
Conclusions
The research questions identified provide insight into public health practitioners’ perceived knowledge gaps and the types of information that would be most useful for informing and advancing PHPR practice. The study also points to a higher level of information need among LHDs than among PHEP awardees. These findings are important for CDC and the PHPR research community to ensure that future research studies are responsive to practitioners’ needs and provide the information required to enhance their capacity to meet the needs of the communities and jurisdictions they serve. (Disaster Med Public Health Preparedness. 2017;11:552–561)