This Management and Organization Review (MOR) special issue on ‘Coopetition and Innovation in Transforming Economies’ aims to explore key features of the strategic relationship between coopetition and innovation in transforming economies. It is generally accepted that innovation can be a fundamental driver for economic growth, new sources of employment, and dwindling economic disparity. However, increasingly activities of innovation no longer take place primarily within the firm but are often the outcome of the overall set of relationships of the firm. The two phenomena of competition and cooperation have become more and more inter-related, thus creating new opportunities, affecting innovation and change. This reality is of special interest in the context of transforming economies’ transition to higher value adding economic growth and development due to, for example, the specific moderating or mediating role of national cultures and philosophical inspiration (e.g., Taoism, Confucianism, Hinduism, and Buddhism) in shaping the coopetitive mindset (Dagnino, Di Guardo, & Padula, 2012) and the potential differentiation between countries and regional ecologies.