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6 results

  • Multidisciplinary Rehabilitation Intervention Activities for People with Migraine: Scoping Review

  • Marie-José Durand, Marie-France Coutu, Thomas Gérard, Marie-Pier Royer, Karine Devantéry, Patricia Godbout, Stéphanie Laprise, Élizabeth Leroux, Marie-Andrée Paquette
  • Journal:
    Canadian Journal of Neurological Sciences , First View
    Published online by Cambridge University Press:
    23 January 2025, pp. 1-10
  • Background:

    Migraine management involves a wide range of clinical rehabilitation practices. This variability hampers the clinical applicability of these protocols. Before proposing any recommendations for migraine interventions, one needs to identify how interventions are generally structured. This study aimed to systematically map the activities in multidisciplinary rehabilitation programs for people with migraine.

    Methods:

    We conducted a scoping review from January 2002 to April 2024 in MEDLINE®, CINAHL, Academic Search Complete, AMED, APA PsycInfo and Academic Search Complete databases. Search terms were related to (i) migraine or headache, (ii) intervention and (iii) multidisciplinary or interdisciplinary care. Language and population inclusion criteria were applied. Two researchers independently screened titles, abstracts and full-text articles and extracted data according to three topics: (i) activities and their modalities, (ii) professionals involved and (iii) tools used.

    Results:

    The activities identified ranged from medication management and a variety of exercise types and lifestyle changes using education strategies to stress management techniques. Psychological interventions were rarely defined and appeared to overlap with education and stress management techniques. Information on treatment delivery was scarce. Professionals from many disciplines were mentioned. The outcomes assessed included migraine or headache characteristics, psychological symptoms, disability and quality of life. No explicit theoretical models were found.

    Conclusions:

    The results highlight the heterogeneity of activities in multidisciplinary interventions for people with migraine. Operationalizing an intervention based on a theoretical model is essential for allowing replications, evaluation and implementation in rehabilitation settings.

  • Assessing the Quality of Care Provided to Older Persons with Frailty in Five Canadian Provinces, Using Administrative Data

  • Cynthia Kendell, Beverley Lawson, Joseph H. Puyat, Robin Urquhart, Arminée Kazanjian, Grace Johnston, Sharon E. Straus, Pierre Durand, Lucille Juneau, Alexis F. Turgeon, France Légaré, Michèle Aubin, Louis Rochette, Anik M.C. Giguere
  • Journal:
    Canadian Journal on Aging / La Revue canadienne du vieillissement / Volume 39 / Issue 1 / March 2020
    Published online by Cambridge University Press:
    22 July 2019, pp. 52-68
    • Article
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  • We examined the quality of care provided to older persons with frailty in five Canadian provinces, using administrative health data. In each province, we identified two cohorts of older persons with frailty: decedents and living persons. Using decision rules, we considered individuals to be frail if they were long-term care residents, terminally ill, or met at least two of seven domains, which were based on frailty scales, geriatrician discussions, and health service utilization indicators. We assessed quality of care using selected quality indicators: decrease in length of hospital stay, decrease in the number of in-patient readmissions, decrease in the number of emergency department visits, increase in the level of family physician continuity of care, decrease in the use of mechanical ventilation, and decrease in the number of admissions to intensive care. Using regression analyses, we also found male sex and older age were associated with poorer quality of care in both cohorts. This study provides baseline data for evaluating future efforts to improve the quality of care provided to older persons with frailty.

  • Effects of lowered serotonin transmission on cocaine-induced striatal dopamine response: PET [11C]raclopride study in humans

  • Sylvia M. L. Cox, Chawki Benkelfat, Alain Dagher, J. Scott Delaney, France Durand, Theodore Kolivakis, Kevin F. Casey, Marco Leyton
  • Journal:
    The British Journal of Psychiatry / Volume 199 / Issue 5 / November 2011
    Published online by Cambridge University Press:
    02 January 2018, pp. 391-397
    Print publication:
    November 2011
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  • Background

    Low serotonin transmission is thought to increase susceptibility to a wide range of substance use disorders and impulsive traits.

    Aims

    To investigate the effects of lowered serotonin on cocaine-induced (1.0 mg/kg cocaine, self-administered intranasally) dopamine responses and drug craving.

    Method

    In non-dependent cocaine users, serotonin transmission was reduced using the acute tryptophan depletion method. Striatal dopamine responses were measured using positron emission tomography with [11C]raclopride.

    Results

    Acute tryptophan depletion increased drug craving and striatal dopamine responses to cocaine. These acute tryptophan depletion-induced increases did not occur in the absence of cocaine.

    Conclusions

    The results suggest that low serotonin transmission can increase dopaminergic and appetitive responses to cocaine. These findings might identify a mechanism by which individuals with low serotonin are at elevated risk for both substance use disorders and comorbid conditions.