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Based on the review of specimens of the genus Bulbothrix s. lat. supported by morphological and chemical evidence, Bulbothrix buapana is described as a new species collected from a tropical dry forest in Oaxaca, Mexico. It differs from other species of Bulbothrix by having coronate apothecia, the presence of ciliate bulbs all over the upper cortex including the amphithecia, and by containing gyrophoric acid as the main medullary substance. Additionally, B. bulbillosa is reported for the first time in North America, this species also characterized by having ciliate bulbs over the upper cortex, but being isidiate, and by the presence of gyrophoric acid in the medulla. Furthermore, B. fungicola and B. tabacina are newly recorded for the state of Oaxaca, B. isidiza for the state of Veracruz, B. subdissecta for the state of Puebla, and B. ventricosa for the states of Morelos and Oaxaca. A thorough revision of Bulbothrix species is proposed, emphasising the correct identification of ciliate bulbs via the diaphanization procedure and the microcrystallization technique for confirming secondary metabolites. A taxonomic key for species of Bulbothrix s. lat. reported in Mexico is provided.
This study presents an analysis of funerary practices at the site of Valdelasilla (Illescas, Toledo, Spain). The methodology integrates the morphological study of burial structures, anthropological analyses, a consideration of grave goods and the radiocarbon dating of human bone. The chronological data indicate funerary activity at the site from the Late Neolithic to the Chalcolithic period. Bayesian modelling confirms the establishment of a planned cemetery by the end of the fifth millennium cal. bc, featuring small burial chambers organized around a larger tomb enclosed by a ditch. The burial chambers, which were constructed from wood, clay and small stones, created distinct spaces for the deceased. This embryonic form of monumentalization, the funerary practices observed and the early chronology link Valdelasilla to other peninsular cemeteries associated with the emergence of megalithism, now identified for the first time on the plateau. The location of the necropolis offers new insights into the role of inland regions in the emergence of Iberian and European megalithism.
This study offers a systematic and theory-informed integrative synthesis of research at the intersection of artificial intelligence (AI) and entrepreneurship. Although interest in this domain has expanded rapidly, existing research remains fragmented, technology centered, and weakly connected to theories of entrepreneurial decision-making. To address this gap, the study adopts a hybrid review design that combines a systematic literature review with bibliometric co-word analysis and thematic synthesis. Based on 372 articles indexed in the Web of Science (WoS) Core Collection (2010–2025), the analysis maps the intellectual structure, thematic landscape, and temporal evolution of AI–entrepreneurship research. Four thematic quadrants are identified, reflecting core applications, transversal foundations, isolated specializations, and peripheral themes. The synthesis shows that AI is largely conceptualized as a functional input, while cognitive and behavioral dimensions of entrepreneurial judgment remain marginal. Building on these insights, the article proposes a cognitively informed research agenda to guide future work.
The European Radiation Dosimetry Group (EURADOS) and the WHO’s Radiation Emergency Medical Preparedness and Assistance Network (REMPAN) have collaborated to review best practices for managing radionuclide intakes through wounds. Rapid response and decisions on wound decontamination, tissue excision, and chelation therapy are based on measurements of the exposed individual and preliminary dose assessments using reasonable default assumptions. The goal is to minimize exposure, prevent tissue reactions, and reduce the risk of stochastic effects.
The management of a contaminated wound is always case-specific, but some general procedures typically apply for a proper evaluation of the contamination case. Medical doctors (surgeons and toxicologists) and internal dosimetrists should work together in the management of the contaminated wound case, with internal dosimetrists providing expert advice to aid clinical decision-making and communication with the patient and his/her family. The ISO standard 20031:2020 provides guidelines on the monitoring and dosimetry for internal exposures due to wound contamination with radionuclides. The Clinical Decision Guide was proposed by the National Council on Radiation Protection and Measurements in its Report 161 to assist physicians in making treatment decisions for individuals with internal radionuclide intakes. Best practices for medical treatment, based on previous experience, are presented here.
To compare verbal memory encoding, storage, and retrieval in patients with schizophrenia (SZ), SZ plus substance use disorder (SZ+), and substance use disorder only (SUD), testing the hypothesis that SZ + group exhibits greater impairment across all processes.
Methods:
A total of 294 male patients under treatment (SZ = 72, SZ+ = 72, SUD = 150) meeting DSM-5 criteria completed the Rey Auditory Verbal Learning Test (RAVLT). RAVLT measures assessed encoding, storage, and retrieval. ANCOVA/MANCOVA, controlling for premorbid IQ, were used to explore group differences.
Results:
Significant differences among groups were observed in all RAVLT measures (F(2,291) > 9.25, p < 0.001, ηp2 > 0.06) except retrieval. Post hoc analyses revealed that both SZ and SZ+ groups showed significant verbal memory impairments (learning trials and storage, interference, short and long-term recall and recognition) compared to the SUD group which performed within the normative range. The SZ and SZ+ groups showed altered values (Z ≥ −1.5) from the second learning trial onward and total learning, and the SZ+ group also for long-term recall and recognition.
Conclusions:
This study confirms the existence of significant verbal memory deficits in both SZ and SZ+ groups compared to SUD. Verbal memory impairment appears as a central feature of SZ spectrum disorders, irrespective of SUD comorbidity. Exacerbated memory impairment in SZ+ compared to SZ on the RAVLT is subtle without reaching significant differences, although consideration of altered Z-scores suggests worse performance in SZ+ in encoding and consolidation processes. Further research should explore clinical variables and moderators of comorbidity effects in SZ.
Autoimmune encephalitis is a new and increasingly well-described entity. The most common is encephalitis caused by antibodies against the N-methyl-D-aspartate receptor on the surface of neurons (NMDAR encephalitis). It is a predominant entity in women and young patients and it is often associated with ovarian teratomas, neuroblastomas, Hodgkin’s lymphomas and others.
NMDAR encephalitis can manifest with a diverse range of neurological and psychiatric symptoms (personality change, anxiety, insomnia, confusion, attentional and short-term memory deficits, emotional lability, psychotic symptoms, language impairment, fluctuations in the level of consciousness, seizures and dysautonomia).
Objectives
Clinical review of Anti-NMDAR Encephalitis for differential diagnosis with Functional Neurologic Disorder.
Methods
Clinical case and literature review.
Results
We present the clinical case of a 27-year-old woman with a history of depression and anancastic personality disorder. The patient went to the Emergency Department different days presenting both neurological (facial paresthesias, hypoesthesia, weakness, high-intensity occipital headache, dizziness, loss of consciousness and anterograde amnesia) and psychiatric symptoms (obsessive thoughts, anxiety, visual and auditory hallucinations). She was admitted to the Neurology Unit. Complementary tests were performed: EEG, cranial CT scan, MRI, lumbar puncture, blood tests (including tumour markers) and urinalysis, founding no alterations suggestive of encephalitis or other systemic pathologies. She was also evaluated by the Psychiatry service. The patient described that as a result of a recent change in her job she presented emotional lability, obsessive ruminative ideas and anxiety. Treatment with Sertraline 100mg/day and Lorazepam 1mg/8 hours was started.
After ruling out autoimmune encephalitis, the patient was diagnosed with Functional Neurologic Disorder, given the temporal relationship of the symptoms with the stressful history at work.
Conclusions
Given their growing prevalence autoimmune causes, such as NMDA anti-receptor antibody encephalitis, should always be considered in the cases of neuropsychiatric alterations. It is very important to carry out a correct organic screening prior to the diagnosis of psychiatric pathology. It is also essential an adequate coordination between different medical departments for an accurate and comprehensive approach to the patient.
The proposed research work aims to carry out a review of the data of the Assertive Community Treatment Program of Segovia, analyzing its importance in certain profiles of psychiatric patients.
Objectives
Review of data from the Segovia Assertive Community Treatment Program from 2020-2024: age, sex, nationality, marital status, level of education, diagnosis, family history, substance use, population, socio-family situation, economic situation, follow-up and admissions in Mental health, social health coordination and disability.
Methods
Data from the Segovia Assertive Community Treatment Program from 2020-2024.
Results
The majority of patients participating in the Segovia Assertive Community Treatment Program between 2020-2024 were Spanish men between 20 and 60 years old. All patients were single, except three separated and one married. Approximately half of them lived alone and the other half with their family of origin. Most had basic education and half were employed. Regarding the consumption of toxic substances, most of them smoked tobacco and some also consumed alcohol or cannabis, and a small number cocaine. Many of them received a financial benefit and had social-health coordination.
The most common diagnosis is schizophrenia, followed by schizoaffective disorder and delusional disorder, most with psychiatric family history. Other diagnoses that the patients presented were: bipolar disorder, personality disorder and obsessive-compulsive disorder. Some of them also had disabilities.
It is important to highlight that 94.12% of patients live in rural areas, many of them more than 30 minutes away by car and with faced great difficulties with public transportation. Many of them were more previous admissions to Psychiatry and an irregular follow-up in Mental Health, but very few had readmissions during the Program. The majority of patients had psychopharmacological treatment, and 7.14% of them had injectable antipsychotic treatment.
Conclusions
A large percentage of patients in the Assertive Community Mental Health Treatment Program are people who live in a rural environment, with a long distance from the nearest mental health center and with difficulties using public transportation, which is why this program is very useful. In these patients to achieve clinical stability, since these patients had irregular follow-up in Mental Health consultations and had numerous admissions to Psychiatry.
This study analyses the evolution of body mass index (BMI) as income increases across the population, controlling for age, sex, educational level, marital status and some lifestyle habits. To this end, a quantile regression, an econometric technique that readjusts the weights of the variables in each quantile to minimize deviations, has been carried out, where the variable that orders the sample is income. We use 316,777 observations from the European Health Interview Survey (EHIS) for these regressions. This approach allows us to separate the regression analyses for low-, middle-, and high-income groups, evidence that as individual income increases, BMI tends to rise. Consequently, individuals with higher incomes exhibit higher BMI levels. Additionally, the estimated parameters for explanatory variables increase with income, signifying that wealthier individuals not only have a greater likelihood of increased BMI but also that socio-economic factors influencing BMI – whether positively or negatively – evince a stronger impact as income levels rise.
Spinal cord atrophy (SMA) affects one in every 1,000 live births in Spain. Cerebral palsy (CP) is the most common cause of chronic motor disability in children, affecting two to three in every 1,000 live births. The Atlas 2030 exoskeleton is the first portable robotic pediatric exoskeleton aimed at facilitating walking in these children. It is used as a complement to other therapies.
Methods
We aimed to compare the efficacy and safety of the ATLAS 2030 exoskeleton with conventional physiotherapy in children aged between four and 12 years with SMA or CP. We conducted a literature search to identify clinical trials and systematic reviews in the PubMed, Embase, Web of Science, and Cochrane Library databases, finding 201 original articles published between 2017 and 2022. No controlled studies were found on the ATLAS 2030 or any other portable device, even after expanding the searches to any robot-assisted gait devices.
Results
Although systematic reviews evaluating the efficacy and safety of robotic orthoses in general were found, there were no specific controlled studies on the ATLAS 2030. The five studies found (two on CP and three on SMA) were of low quality and did not show conclusive results in terms of efficacy and safety. However, some of them suggested that this technology could provide significant improvements in acceptability, range of motion, and spasticity. With respect to safety there appeared to be no evidence of serious adverse effects from its use, reinforcing the developer’s initial hypothesis that the technology is safe.
Conclusions
Although the available evidence is very limited, the ATLAS 2030 appears to show efficacy in some gait-related outcomes without serious adverse effects. To demonstrate safety and efficacy, randomized controlled trials are required that compare the ATLAS 2030 with conventional physiotherapy, with more participants and a longer duration, and are conducted by independent expert groups without conflicts of interest.
A functional traits approach was adopted to examine patterns of fish diversity in relation to environmental and spatial variables and for comparison with findings from earlier analyses of fish taxonomic diversity in a nearly pristine river in the Llanos region of Colombia. Fishes were surveyed during the low-water period at 34 sites along the longitudinal fluvial gradient of the Bita River, a clearwater tributary of the Orinoco River. We compiled a matrix of 37 traits associated with locomotion, feeding, and defense for 132 species to compute functional β diversity metrics among four reaches along the entire longitudinal fluvial gradient and also within reaches. Functional redundancy (trait under-dispersion) was found to be common throughout the fluvial gradient. Functional β diversity was high at both spatial scales, with widespread evidence of functional nestedness and functional turnover, especially in upper reaches. In the Bita River, environmental filtering and stochastic processes, such as random dispersal, appear to be the dominant mechanisms influencing fish functional diversity. Inferences derived from analysis of functional versus taxonomic diversity are largely congruent, although analysis of functional β diversity found more evidence of nestedness than turnover at both spatial scales. Both lines of evidence stress the importance of habitat heterogeneity and aquatic habitat connectivity for conservation of high species diversity in this system.
This article analyses the self-perceived health of the population surveyed by the European Health Interview Survey (EHIS), with 316,277 observations. The main novelties of this research are: first, we use the econometric technique of quantile regression, which will allow us to distinguish the respondent’s income level. Second, the personal, social, lifestyle and macroeconomic context dimensions of the respondents are considered simultaneously as determinants of self-perceived health. In this way, we will be able to see what the determinants of health are, and whether they vary with income. Finally, it is evident that there are indeed different responses to the same stimulus depending on the level of income, especially in the elasticity of the response, seeing how the higher the income, the more or less the same stimulus influences a person. In addition, it is established that age, nationality and employment status are the most influential variables in self-perceived health.
There is heterogeneity in the long-term trajectories of depressive symptoms among patients. To date, there has been little effort to inform the long-term trajectory of symptom change and the factors associated with different trajectories. Such knowledge is key to treatment decision-making in primary care, where depression is a common reason for consultation. We aimed to identify distinct long-term trajectories of depressive symptoms and explore pre-treatment characteristics associated with them.
Methods
A total of 483 patients from the PsicAP clinical trial were included. Growth mixture modeling was used to identify long-term distinct trajectories of depressive symptoms, and multinomial logistic regression models to explore associations between pre-treatment characteristics and trajectories.
Results
Four trajectories were identified that best explained the observed response patterns: “recovery” (64.18%), “late recovery” (10.15%), “relapse” (13.67%), and “chronicity” (12%). There was a higher likelihood of following the recovery trajectory for patients who had received psychological treatment in addition to the treatment as usual. Chronicity was associated with higher depressive severity, comorbidity (generalized anxiety, panic, and somatic symptoms), taking antidepressants, higher emotional suppression, lower levels on life quality, and being older. Relapse was associated with higher depressive severity, somatic symptoms, and having basic education, and late recovery was associated with higher depressive severity, generalized anxiety symptoms, greater disability, and rumination.
Conclusions
There were different trajectories of depressive course and related prognostic factors among the patients. However, further research is needed before these findings can significantly influence care decisions.
This project in southern Chile's Lake Region analysed late Pleistocene human–environment interactions. Two field seasons in 2020 and 2022 provided a new lithic collection dating to around 17 300–12 800 cal BP, which indicates human presence in north-western Patagonia prior to the Younger Dryas period.
We analyze the internal structure of two polythermal glaciers, Hurd and Johnsons, located on Livingston Island, Antarctica, using 200 and 750 MHz GPR data collected in 2003/04, 2008/09 and 2016/17 field campaigns. Based on the different permittivities of snow and ice, we determined the thickness distribution of the end-of winter snow cover and of the cold ice layer. Their knowledge is fundamental for mass balance and glacier dynamics studies due to the different densities and rheological properties of such media. The average measured thicknesses for the snow and cold ice layers (the latter including the snow layer) were of 1.44 ± 0.09 and 29.1 ± 1.5 m, and their corresponding maxima were of 2.45 ± 0.21 and 80.8 ± 2.5 m. GPR snow profiling allowed for extension of the coverage of the snow thickness survey, but added little information to that supplied by snow pits, stake readings and manual snow probing, because of the multiplicity of reflections within the seasonal snowpack caused by internal ice layers and lenses. The polythermal structure determined for Hurd Glacier fits into the so-called Scandinavian type, seldom reported for the Antarctic region.
Considered the epidemic of the 21st century by the WHO, obesity is a global problem that is on the rise and will continue to increase in the coming years. Spain and Andalusia, in particular, are no exception to this pathology, which has tripled since the 1970s, representing a public health challenge. The aim of this study is to analyse the socioeconomic determinants of this pathology, with special emphasis on answering the question of what has a greater influence on overweight, education level, or income. For this purpose, we have used the European Survey of Health in Spain (ESHS-2020), a microdata base, with a total of 22,072 valid individual observations (of which 2,820 belong to the Andalusian population). Results we obtain in our estimations of qualitative response models reveal that, although both income and educational attainment could be effective in the fight against overweight, the social gradient of this health problem is greater with respect to educational attainment. Additionally, there are many other variables and other factors related to the individual’s overweight (mental health, subjective state of health, oral health, among others) which are much less explored and which must be considered in health policies to combat this disease.
The Antarctic Peninsula Ice Sheet (APIS) has become a significant contributor to sea-level rise over recent decades. Accurately estimating the ice discharge from the outlet glaciers of the APIS is crucial to quantify the mass balance of the Antarctic Peninsula. We here compute the ice discharge from the outlet glaciers of the APIS north of 70${^\circ }$S for the five most widely used ice-thickness reconstructions, using a common surface velocity field and a common set of flux gates, so the differences in ice discharge can be solely attributed to the differences in ice thickness at the flux gates. The total volumetric ice discharge for 2015–2017 ranges within 45–141 km3 a−1, depending on the ice-thickness model, with a mean of 87 ± 44 km3 a−1. The substantial differences between the ice-discharge results, and a multi-model normalized root-mean-squared deviation of 0.91 for the whole data set, reveal large differences and inconsistencies between the ice-thickness models, giving an indication of the large uncertainty in the current ice-discharge estimates for the APIS. This manifests a fundamental problem of the region: the scarcity of appropriate ice-thickness measurements and the difficulty of the current models to reconstruct the ice-thickness distribution in this complex region.
Knowledge of frontal ablation from marine-terminating glaciers (i.e., mass lost at the calving face) is critical for constraining glacier mass balance, improving projections of mass change, and identifying the processes that govern frontal mass loss. Here, we discuss the challenges involved in computing frontal ablation and the unique issues pertaining to both glaciers and ice sheets. Frontal ablation estimates require numerous datasets, including glacier terminus area change, thickness, surface velocity, density, and climatic mass balance. Observations and models of these variables have improved over the past decade, but significant gaps and regional discrepancies remain, and better quantification of temporal variability in frontal ablation is needed. Despite major advances in satellite-derived large-scale datasets, large uncertainties remain with respect to ice thickness, depth-averaged velocities, and the bulk density of glacier ice close to calving termini or grounding lines. We suggest ways in which we can move toward globally complete frontal ablation estimates, highlighting areas where we need improved datasets and increased collaboration.
During the second half of the 20th century, the Antarctic Peninsula region has undergone a long and sustained warming period, followed by a shorter but also sustained cooling period, and then a very recent return to warming conditions. All of these have profoundly impacted the glaciers peripheral to the Antarctic Peninsula. This paper focuses on the analysis of the surface mass balance monitoring of such glaciers by the glaciological method, complemented by the analysis of mass-balance estimates by geodetic methods, as well as frontal ablation estimates. We aim to summarize the current knowledge and outline the main challenges faced by investigating the mass balance of such peripheral glaciers and their current contribution to sea-level rise.
The effects of the farming system (conventional-organic-abandoned) and soil management (native cover crop vs tillage) on vascular plant species were analyzed in sloping olive groves (>20%) in 20 different locations in Andalusia, SE Spain. The soil management techniques included Organic Tillage (OT), Organic Cover Crops (OC), Conventional Tillage (CT), Conventional Non-Tillage (CNT), Abandoned Cover Crops (AC) and Abandoned Woody (AW). Data for the vascular plant species were recorded through three line transects of 30 m with a bar perpendicularly touching every 1 m of the measuring tape. Environmental variables were also recorded at plot level to assess their influence. Dependent variables, such as species abundance, richness and diversity indexes were studied using univariate analysis (one-way ANOVA, Kruskal–Wallis test) while multivariate statistics (ANOSIM, SIMPER, DCA) were used for analyzing the data matrices. We found that the different combinations of farming system and soil management affect biological diversity in terms of individual abundance, plant cover, species richness and diversity, species and family composition. Life forms and species distribution patterns are also affected. The main environmental variables affecting the plant taxa were those related with soil and climate characteristics, slope, olive age and intensive land uses at landscape level, including the percentage of artificial surfaces. The lowest levels of biodiversity (e.g., species richness) were found in the tilled olive groves (CT = 8.1 sp. ± 2.2, OT = 10.0 sp. ± 5.4). Surprisingly, the organic tilled groves (OT) were very poor in species compared to those with native plant cover (OC = 27.9 sp. ± 3.0). The latter, however, showed similar species richness to the abandoned olive groves (AC = 21.2 sp. ± 3.7, AW = 27.2 sp. ± 3.0). Possible solutions for increasingly uncompetitive sloping olive groves include conversion to organic with native plant cover or abandonment for rewilding.
Calculation of the calving loss of tidewater glaciers depends on accurate bedrock information. In regional to global-scale projections of future tidewater glacier evolution this dependence is problematic. Bedrock topographies are often unknown and can only be modelled from surface properties. Existing approaches, however, mostly underestimate the ice thickness towards the calving fronts of marine-terminating glaciers. This implies a compromised performance of global-scale projection models which often employ functions of water depth at the calving fronts of tidewater glaciers. Here, we present a sensitivity study that analyses the impact of five different bedrock datasets on projected mass losses from the tidewater glacier Hansbreen in southern Svalbard. Our modelling study calculates the glacier's response to artificial mass-balance forcing. We show that bedrock inaccuracies may lead to a substantially deviating retreat behaviour. The common underestimation of frontal ice thickness/water depth in the modelled bedrock datasets induces an underestimation of sea level-relevant mass losses over the first several decades of modelling. The duration of this period is reduced when assuming warmer climates. Our results thus underline the importance of accurate bedrock topography data for the reliability of glacier evolution projections and for the accuracy of the temporal trajectories of related sea level-relevant mass losses.