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Widely popular amongst exam candidates, Dr Podcast Scripts is a great way to revise for your Final FRCA. Providing questions and model answers spanning the breadth of the exam syllabus and fully updated in this second edition, this revision aid allows you to experience the format of questions likely to be asked and it provides tips on how to excel in the exam. Supplemented with helpful illustrations to explain answers, you will learn what to expect in the exam and how differently worded questions on the same topic require modified approaches. Written and updated by successful candidates providing insight and experience of the exam, all the material has been reviewed by experienced consultants with detailed knowledge of the educational standards. If you are preparing for your Final FRCA exam, Dr Podcast Scripts for the Final FRCA is a must!
Spectra have been obtained with the multi-fibre instrument 2dF on the Anglo-Australian Telescope of 89 candidate main sequence stars in the globular cluster M55 (NGC 6809). Radial velocities and Gaia proper motions confirm 72 candidates as cluster members. Among these stars one stands out as having a substantially stronger G-band (CH) than the rest of the member sample. The star is a dwarf carbon star that most likely acquired the high carbon abundance ([C/Fe] $\approx$ 1.2 $\pm$ 0.2) via mass transfer from a $\sim$1$-$3 M$_{\odot}$ binary companion (now a white dwarf) during its AGB phase of evolution. Interestingly, M55 also contains a CH-star that lies on the cluster red giant branch – the low central concentration/low density of this cluster presumably allows the survival of binaries that would otherwise be disrupted in denser systems. The existence of carbon stars in six other globular clusters is consistent with this hypothesis, while the origin of the carbon-enhanced star in M15 (NGC 7078) is attributed to a merger process similar to that proposed for the origin of the carbon-rich R stars.
We present a chemo-dynamical study conducted with 2dF$+$AAOmega of $\sim 6\,000$Gaia DR3 non-variable candidate metal-poor stars that lie in the direction of the Galactic plane. Our spectral analysis reveals 15 new extremely metal-poor (EMP) stars, with the lowest metallicity at $\left[\text{Fe/H}\right] = -4.0 \pm 0.2$ dex. Two of the EMP stars are also carbon enhanced, with the largest enhancement of $\left[\text{C/Fe}\right] = 1.3 \pm 0.1$ occurring in a dwarf. Using our $\left[\text{C/Fe}\right]$ results, we demonstrate that the number of carbon-depleted stars decreases with lower metallicities, and the fraction of carbon-enhanced stars increases, in agreement with previous studies. Our dynamical analysis reveals that the fraction of prograde and retrograde disk stars, defined as $z_{\mathrm{max}} \lt 3$ kpc, with $J_{\phi}/J_{\mathrm{tot}} \gt 0.75$ and $J_{\phi}/J_{\mathrm{tot}} \lt -0.75$, respectively, changes as metallicities decrease. Disk stars on retrograde orbits make up $\sim 10$% of all the stars in our sample with metallicities below $-2.1$ dex. Interestingly, the portion of retrograde disk stars compared with the number of kinematically classified halo stars is approximately constant at $4.6$% for all metallicities below $-1.5$ dex. We also see that $J_{\phi}$ increases from $380 \pm 50$ to $1320 \pm 90$ km s$^{-1}$ kpc across metallicity range $-1.5$ to $-1.1$, consistent with the spin-up of the Galactic disk. Over the metallicity range $-3.0 \lt \left[\text{Fe/H}\right] \lt -2.0$, the slopes of the metallicity distribution functions for the prograde and retrograde disk stars are similar and comparable to that for the halo population. However, detailed chemical analyses based on high-resolution spectra are needed to distinguish the accreted versus in situ contributions. Finally, we show that our spectroscopic parameters reveal serious systematics in the metallicities published in recent studies that apply various machine learning techniques to Gaia XP spectra.
In functional magnetic resonance imaging (fMRI), the blood oxygenation level dependent (BOLD) signal is often interpreted as a measure of neural activity. However, because the BOLD signal reflects the complex interplay of neural, vascular, and metabolic processes, such an interpretation is not always valid. There is growing evidence that changes in the baseline neurovascular state can result in significant modulations of the BOLD signal that are independent of changes in neural activity. This paper introduces some of the normalization and calibration methods that have been proposed for making the BOLD signal a more accurate reflection of underlying brain activity for human fMRI studies.
Functional magnetic resonance imaging (fMRI) is a noninvasive method for measuring brain function by correlating temporal changes in local cerebral blood oxygenation with behavioral measures. fMRI is used to study individuals at single time points, across multiple time points (with or without intervention), as well as to examine the variation of brain function across normal and ill populations. fMRI may be collected at multiple sites and then pooled into a single analysis. This paper describes how fMRI data is analyzed at each of these levels and describes the noise sources introduced at each level.
This paper presents an improved setup for radiocarbon analysis of water-soluble organic carbon based on wet chemical oxidation as installed at the Laboratory for the Analysis of Radiocarbon with AMS (LARA) at the University of Bern. The implementation of a non-dispersive infrared CO2 detector allows more precise and accurate quantification of carbon amounts in samples and establishes the possibility of simple monitoring of the efficacy of flushing and sampling processes. A detailed blank assessment unveiled undesired oxidation of different materials and sample temperature as critical factors regarding the level of constant contamination. Contamination arising from oxidation of septum pieces and carbon-based glues in conventional sampling needles was minimized by developing a glass-sintered needle. This new needle was also designed to be longer, reducing the minimum amount of sample solution needed to 2 mL. The oxidation time and temperature (1 hr at 75°C) were optimized to further decrease contamination during analyses of samples with carbon amounts of up to ∼50 µg. With these improvements, we now report low constant contamination levels of 0.62 ± 0.12 µg C (with F14C of 0.19 ± 0.04), whereas the cross contamination factor was determined to be 0.25 ± 0.07%.
Knowledge of sex differences in risk factors for posttraumatic stress disorder (PTSD) can contribute to the development of refined preventive interventions. Therefore, the aim of this study was to examine if women and men differ in their vulnerability to risk factors for PTSD.
Methods
As part of the longitudinal AURORA study, 2924 patients seeking emergency department (ED) treatment in the acute aftermath of trauma provided self-report assessments of pre- peri- and post-traumatic risk factors, as well as 3-month PTSD severity. We systematically examined sex-dependent effects of 16 risk factors that have previously been hypothesized to show different associations with PTSD severity in women and men.
Results
Women reported higher PTSD severity at 3-months post-trauma. Z-score comparisons indicated that for five of the 16 examined risk factors the association with 3-month PTSD severity was stronger in men than in women. In multivariable models, interaction effects with sex were observed for pre-traumatic anxiety symptoms, and acute dissociative symptoms; both showed stronger associations with PTSD in men than in women. Subgroup analyses suggested trauma type-conditional effects.
Conclusions
Our findings indicate mechanisms to which men might be particularly vulnerable, demonstrating that known PTSD risk factors might behave differently in women and men. Analyses did not identify any risk factors to which women were more vulnerable than men, pointing toward further mechanisms to explain women's higher PTSD risk. Our study illustrates the need for a more systematic examination of sex differences in contributors to PTSD severity after trauma, which may inform refined preventive interventions.
To evaluate the trends in the healthiness of packaged food purchases of Australian consumers before and after the introduction of the Health Star Rating (HSR) nutrition labels.
Design:
Panel data analysis and difference-in-differences analysis.
Setting:
The Australian Government endorsed HSR nutrition labels for voluntary implementation on packaged foods in June 2014. We analyse the packaged food purchases of households across all major supermarkets before (January 2014 to June 2014) and after (June 2014–Dec 2018) the introduction of HSR.
Participants:
6284 members of a panel of households across Australia reporting their grocery purchases to a market research company (Nielsen Homescan panel).
Results:
The healthiness of household food purchases exhibited a U-shaped trend – decreasing from 2014 to 2017, and then increasing from 2018, corresponding to the time when a higher proportion of products were HSR-labelled. Households that purchased a higher proportion of HSR-labelled products had healthier household purchases overall. Further, the healthiness of households’ category-specific food purchases was positively associated with the proportion of HSR-labelled products in categories where HSR was adopted, relative to control categories where HSR was not adopted.
Conclusions:
In Australia, once a substantial number of packaged food products adopted the voluntary HSR summary indicator, we observed an increasing trend in the healthiness of household food purchases. Widespread adoption of a nutrition summary indicator, such as HSR, on packaged food is likely to be beneficial for population health.
A series of synthetic goethites containing varying amounts of Si and P dopants were characterized by X-ray powder diffraction, electron diffraction, microbeam electron diffraction, and Mössbauer spectroscopy. Very low level incorporation produced materials having structural and spectral properties similar to those of poorly crystalline synthetic or natural goethite. At higher incorporation levels, mixtures of noncrystalline materials were obtained which exhibited Mössbauer spectra typical of noncrystalline materials mixed with a superparamagnetic component. Microbeam electron diffraction indicated that these mixtures contained poorly crystalline goethite, poorly crystalline ferrihydrite, and a noncrystalline component. If the material was prepared with no aging of the alkaline Fe3+ solution before the addition of Na2HPO4 or Na2SiO3, materials were obtained containing little if any superparamagnetic component. If the alkaline Fe3+ solution was aged for 48 hr before the addition, goethite nuclei formed and apparently promoted the precipitation of a superparamagnetic phase. The Mössbauer-effect hyperfme parameters and the saturation internal-hyperfine field obtained at 4.2 K were typical of those of goethite; however, the Mössbauer spectra indicated that the ordering temperature, as reflected in the relaxation rate and/or the blocking temperature, decreased with increasing incorporation of Si and P. The complete loss of crystallinity indicates that Si and P did not substitute for Fe, but rather adsorbed on crystal-growth sites, thereby preventing uniform crystal growth.
Edited by
Richard Williams, University of South Wales,Verity Kemp, Independent Health Emergency Planning Consultant,Keith Porter, University of Birmingham,Tim Healing, Worshipful Society of Apothecaries of London,John Drury, University of Sussex
This case study illustrates approaches to promoting the wellbeing of and initiating psychosocial care to support the mental health of the staff of public sector services in the UK. It focuses on staff who work in emergencies, including in the fire and rescue, police, ambulance, and search and rescue services, often referred to in the UK as the Blue Light services. This case study provides information illustrating what can be done to assist the work of employing organisations to promote the mental health of all employees – that is, senior, middle, junior, general, and professional managers and their staff. It describes important concepts in planning and in delivering interventions.
Inside Wembley Stadium, the men’s England manager, Gareth Southgate, huddles his players together for a final team talk before the players step up to take their penalty kicks. First for England is Harry Kane, who scores with a shot that is low and to the goalkeeper’s right. Next is Harry Maguire, who smashes the ball into the top right of the goal. However, Marcus Rashford hits the post and Jadon Sancho’s and Bukayo Saka’s efforts are saved by Italian goalkeeper Gianluigi Donnarumma. It is the final of the UEFA (Union of European Football Associations) European Football Championship (Euro 2020), held in July 2021 due to the COVID-19 pandemic, and England have been defeated on penalties. Sadly, the online racist abuse which followed soured what should have been a proud moment for English football, as the national men’s team had reached their first major tournament final since 1966.
After the penalty kicks, in the ensuing moments online, the three young England players who missed theirs were rendered Black and ‘foreign’ above anything else, thereby exposing people’s deeply held views concerning race relations. Of particular interest here is the fact that a Fédération Internationale de Football Association (FIFA) report released in June 2022 highlighted that more than a third of the online abuse during the final came from online accounts based in the United Kingdom (UK). To offer further context, the abuse mirrored online reactions a decade prior towards Black English players Ashley Cole and Ashley Young, who also missed penalties against Italy during Euro 2012 (Press Association, 2012). The Euro 2020 case illustrates both the ease with which online racism is expressed and its frequency – it sadly represents yet another chapter in the history of online racism within football. What is clear is that forms of hate and forms of racism are evolving, with much of this moving online. Indeed, while racist chants and insults, and even bananas, were once hurled at players inside football stadiums, we can now observe these epithets in multiple digital forms. Many strategies (past and present) have sought to challenge online racism in football, some being more effective than others.
To examine differences in noticing and use of nutrition information comparing jurisdictions with and without mandatory menu labelling policies and examine differences among sociodemographic groups.
Design:
Cross-sectional data from the International Food Policy Study (IFPS) online survey.
Setting:
IFPS participants from Australia, Canada, Mexico, United Kingdom and USA in 2019.
Participants:
Adults aged 18–99; n 19 393.
Results:
Participants in jurisdictions with mandatory policies were significantly more likely to notice and use nutrition information, order something different, eat less of their order and change restaurants compared to jurisdictions without policies. For noticed nutrition information, the differences between policy groups were greatest comparing older to younger age groups and comparing high education (difference of 10·7 %, 95 % CI 8·9, 12·6) to low education (difference of 4·1 %, 95 % CI 1·8, 6·3). For used nutrition information, differences were greatest comparing high education (difference of 4·9 %, 95 % CI 3·5, 6·4) to low education (difference of 1·8 %, 95 % CI 0·2, 3·5). Mandatory labelling was associated with an increase in ordering something different among the majority ethnicity group and a decrease among the minority ethnicity group. For changed restaurant visited, differences were greater for medium and high education compared to low education, and differences were greater for higher compared to lower income adequacy.
Conclusions:
Participants living in jurisdictions with mandatory nutrition information in restaurants were more likely to report noticing and using nutrition information, as well as greater efforts to modify their consumption. However, the magnitudes of these differences were relatively small.
Several hypotheses may explain the association between substance use, posttraumatic stress disorder (PTSD), and depression. However, few studies have utilized a large multisite dataset to understand this complex relationship. Our study assessed the relationship between alcohol and cannabis use trajectories and PTSD and depression symptoms across 3 months in recently trauma-exposed civilians.
Methods
In total, 1618 (1037 female) participants provided self-report data on past 30-day alcohol and cannabis use and PTSD and depression symptoms during their emergency department (baseline) visit. We reassessed participant's substance use and clinical symptoms 2, 8, and 12 weeks posttrauma. Latent class mixture modeling determined alcohol and cannabis use trajectories in the sample. Changes in PTSD and depression symptoms were assessed across alcohol and cannabis use trajectories via a mixed-model repeated-measures analysis of variance.
Results
Three trajectory classes (low, high, increasing use) provided the best model fit for alcohol and cannabis use. The low alcohol use class exhibited lower PTSD symptoms at baseline than the high use class; the low cannabis use class exhibited lower PTSD and depression symptoms at baseline than the high and increasing use classes; these symptoms greatly increased at week 8 and declined at week 12. Participants who already use alcohol and cannabis exhibited greater PTSD and depression symptoms at baseline that increased at week 8 with a decrease in symptoms at week 12.
Conclusions
Our findings suggest that alcohol and cannabis use trajectories are associated with the intensity of posttrauma psychopathology. These findings could potentially inform the timing of therapeutic strategies.
Melincourt (1817), Thomas Love Peacock's only three-volume novel, is also his most comprehensive work. In it, he explores a broad range of controversies: the dangers of 'paper money'; British consumers' complicity in slavery; the inequities of the current system of parliamentary representation; the problem of differentiating between human beings and other animals; and, most centrally, the question of whether and how the human condition might be improved. Peacock's brilliant synthesis of courtship novel and quest romance can only be fully appreciated against its colourful and fraught historical background, and Gary Dyer expertly equips readers with the historical and literary awareness required to recognise it as one of Peacock's most stimulating works. Vividly illuminating its remarkable plot – from the suitors' courtship of Anthelia Melincourt to the rescue party comprised of Sylvan Forester, Mr Fax and the chivalrous 'oran outang' Sir Oran Haut-ton – this edition makes Melincourt more accessible than ever before.